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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FGFR1OP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11116
Official gene symbolFGFR1OP
Full nameFGFR1 oncogene partner
Aliases,FOP,
Gene summaryThis gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q27
Gene position167412816 - 167454066  Map Viewer
Gene orientationplus
Gene size41251 bp
Gene sequence
OMIM ID605392