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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLK8 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 11202 Official gene symbol KLK8 Full name kallikrein-related peptidase 8 Aliases ,HNP,NP,NRPN,PRSS19,TADG14, Gene summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.3-q13.4 Gene position 51504958 - 51499264  Map Viewer Gene orientation minus Gene size 5695 bp Gene sequence >KLK8:complement(23767482..23773176):Length=5695 GTTCCCAGAAGCTCCCCAGGCTCTAGTGCAGGAGGAGAAGGAGGAGGAGCAGGAGGTGGA GATTCCCAGTTAAAAGGCTCCAGAATCGTGTACCAGGCAGAGAACTGAAGTACTGGGGCC TCCTCCACTGGGTCCGAATCAGTAGGTGACCCCGCCCCTGGATTCTGGAAGGTGAGGTGC AGAGGTACTCAGATACAGACATCAGGCCCCGGACCCTCCTTCTCCAGATTCCAGGACCCC AGCCTCAGATGCCCTTCTCTGTCGAGATCCAGCAGTCTGGACCCCGGCTTCCTCCTCTCC CTAATTTAGGAGTCCCAGCTCCCAGCTCCCTGTCCCCTCAGACCCAGACATCGAGGACTC CCCCCTCCCTTGGAATGTAGGAATCCAGTCCCCCAGCCTCCTCCTTCCTCCAGAGAAGCC CAGAACAGCCCCAGATACTCTCGGCTGCCTCCCCAGTGCCCAAATCCAGAACTGGGAGCT CAGGCTCCTCCTTCCTGTTTACCGGCCCCGCCCTCTCCATTTCCCAGACCTCACCATGGG ACGCCCCCGACCTCGTGCGGCCAAGACGTGGATGTTCCTGCTCTTGCTGGGGGGAGCCTG GGCAGGTGAGGAGGGTTGCGGAGGCCTCCGGAGGGGAGGGATCTGAAGGCAGCAGTGGCG CTGGGGAGTCTGTGGGAATGCCGCGGGGGTTATGTGGGTGCGTGTGCACGGATGTGAAGA GTGCGATACGGTGCAGGAGCCTCTGTGGGCTTTCCTCAGGGTGGACAGAGGCAAGAAACA GGTAGCAGCAGGTAGGAGTAGGTTCCGTGATGCTGTAAATTGTCTGAATAGCTACAGCCT TTGGGGGCTGCTTGCTTGGGGGCATAGATTCACCTGGGAGTACTCGGGGCCTGTAGACTC ATGTGGAAGCATGTGGGGGCATTCTTGGGTGTGTGACTCTTGTATGATGACACATGGACT GAAATGAGTGTCCCCGTGTGGCAGCGTGTGGAAGCCTGGACCTCCTCACTAAGTTGTATG CGGAGAACTTGCCGTGTGTCCATTTGAACCCACAGTGGCCTTCCCAGCCCTCGCACTGCC CCAGAGGGTGGCGATCCAACCCTCTCCCTCCTGCTGCAGGACACTCCAGGGCACAGGAGG ACAAGGTGCTGGGGGGTCATGAGTGCCAACCCCATTCGCAGCCTTGGCAGGCGGCCTTGT TCCAGGGCCAGCAACTACTCTGTGGCGGTGTCCTTGTAGGTGGCAACTGGGTCCTTACAG CTGCCCACTGTAAAAAACCGTGAGTGGATGATGGGGGCAGAGGTCAGCTGGGGCTTAAGG AAAGAGGGGGCTGGGGTTTCGACTCAGGAAGGAGAGAGCTGAGGACTGGACTCCTGGGTC TGAAGGAGGAGGGGGCTGGGGGCAATACCCCTGCCTGGGTCCCAAACTATCCCCACCATT ACAGGAAATACACAGTACGCCTGGGAGACCACAGCCTACAGAATAAAGATGGCCCAGAGC AAGAAATACCTGTGGTTCAGTCCATCCCACACCCCTGCTACAACAGCAGCGATGTGGAGG ACCACAACCATGATCTGATGCTTCTTCAACTGCGTGACCAGGCATCCCTGGGGTCCAAAG TGAAGCCCATCAGCCTGGCAGATCATTGCACCCAGCCTGGCCAGAAGTGCACCGTCTCAG GCTGGGGCACTGTCACCAGTCCCCGAGGTAGTGGGCTTGTCCACTAATGGGAGGGAGAGG AGGAGCTGGTTGGCCCAGTGGAACCCAAGCTATTGGCAAAGCTTGGTCCCCCAGAGGGAG ACAAAGAAGGGAAAGTGATCATGATGTTGAGATTCACAAGCAGGAGTCATATGAGAAGCC TCGAAGATCTGACTACTAACAAGAGTGGTGAGAGAAAGAACCAACTAGCAGATTGTTAAG CAGGGCCAGAAAAGCCCATCCTGTATGGCGGAGAGCACTACCCTATGGGACCTTTGGTTG TATAGGATTTTATATAATCTTAACACACTTGGGATATTTGGACTTCTCAGAGGCCCAGGA AAACAGGCTCCTAAGCACCTTCTCCCCCACCTCCCTCCTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTGCAGGGGGACACAGTTTCACTCAATCGCCCAGGCTGGAGTG CAGTGGCACAATCTCAGCTCACTACAATCTCTGCCTCCTGGGTTTAAGCGATTCTCGAAC CTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCGCCACCACGCGAGCTAATTTTTGTA TTTGTTGTAGAGACAGGGTTTCGCCATGTTGACCAGGCTGGTCTCGAACTCCTGACCTCA AGTGATCTGCCCGCCTCGGCCTACCAAAGTGCTGGGATTACAAGCATGAGCCACCGCCCC TGGCCTTTTTCTCCTTCTTGAACCCAGGAAACCTGGGCCCTGGTCACCTCTTCCCTCAGA CCCGGGAGTCTAGGCCCTTCTTCTCCCAGGACCCAGCAGTCCTAGCTCCCTCTTGACTCT GGACCCCAAAATCTGGACCTCCAATGAAGCTGTCCCTTTGGGACTCCAGAATCCAGAGAG CCCCTCGCCTTCCTTCACAGTGAAAACATTGGGACTCACCTAAGAGAGTCAAGGAGCTTC TCCAGGAAGTGGCAAAGTCAGCATTCAGGTCCCTGCCTGCCTCACTCCTGCTCTGAATGC TTTGGATGAGACAGTTTGCGGCTGTGGAAACACACGTGCTCGCAAATCAAGTAGATCAGT TCAAACTATGGCTCTGCCCTTTCTCCCTGGGCAAATTCCTTTCCATCTCTGAGCCTCACT TTCCTTATCTGCAAAATGGGAATCATTAACCAATAGATTTTTTAGCTACGTGAGGGTTCA GGTTACATCAGTTTTCTTCATTGTGTTCTCCTAGTGCTCAGAATGGTGCCTGCTACATGG TAGATGCTCAATAAATATTTGTTGAATGGATGACCTGATGAATAAATAATGAAATGAATG AATGCATCTCTCCTTCAAAGCGCTGTTGTGAGGATTAAATGAGATTATGAGCATATTGCT TTTGGCACGTAGAGATGCCAGATGGAAGTTTTTCCCCCTCAAAGAGGCTTTGGAGAAGTC TATTCCTCAAAAGAGGTTAATAAAAAAGATCAATTCCACCTTCAATCATTAATTCAACTC TTATTTACTGAGCACCTAGTATGCCTGAGGTGCTGTTGCAGGCGCTGGATATACAGCCAT GAGCAAACTGTACAAAGTCCTTGTCGTTATGGAGTTGCAAGCTAGGTGGGAGAAATAGAC AATAAACAAATACACATAAAATAAAACATTAGGCAAAGTGCTGTAAGGAAATATTGTGGA GCGTAAAAGGATAGGGAGTAATGGAGGGATGGTATTTTTTAATTCGAGTGGTCAGGGAAG GCTTCCAGGAGGAGGTGACACTTGGAAGGAGCAGGATTTAGCACAGATTGAGGACCCGGT TGTCTGAGGGCAGGAAGACTGGAAAGAGAGGGTCAGAGGTATCATAAAGGGGCACCTCCA AGTAACCCCCAGCCCCTTGATTTGAAAATGGCTCAGGGTAAGAAAAAACACGTGAGATCC AAGGGCCCCTCTCTAGATGGAGAAAGCCCAATAGCAACAAGTACAGCTTCGTTTAATGTG GTGAGAAGTGATGTCCCCTGTGCACAGTGTCAGAAAATTCCCCCATGCAGCTGGAAAACT CCCCCATTACATCCTGGAAAGAAAGGGGGTTAGATCCAGACAGGGATGGAGGCAAAGGGC TGCTCTCTCAGGGAACCTTACAACCTCTTCCCCCTCAGAGAATTTTCCTGACACTCTCAA CTGTGCAGAAGTAAAAATCTTTCCCCAGAAGAAGTGTGAGGATGCTTACCCGGGGCAGAT CACAGATGGCATGGTCTGTGCAGGCAGCAGCAAAGGGGCTGACACGTGCCAGGTGAGCAA TTTCTGAAATCCTTCTCCTCACACATCCCTCATTGCCCTCTCGAGGTTCAAGGCTTGGAT GGGGGTGGGGGTGGTAAGGGAGTGACCCCAAAGACTTGGCACCCGGAGTGTTCACCCCTA TCTCTACGGATTGGGAGCCAGGTTCAGAGAAGCCAAACTCTCTCTCTGAAAGTCACACTG CATAGGGATTAGGAGCATTGAATTGCTGCTGCTGTTTTCTTTCGAACGCTTAACTACAGG ATGGGATGCAGAGTTGGGGGCTATAGAGGGTGGGGTAGATGTCCAGCAAGGAGAGAGTCT GAGGCTAGAGTTTAGACGAGTTGCCTGCTCTCTGGTTCCCAGCATTACATCGTGGAATTT GTGCCGACTTTACCACCGGCCCGGTGGTCAGCCACTTTTCTTTGAGACCGGGCTAGAATC CCAAGGCTGGTTCCCTTCTCCTGTGATTGGTTCCTTGGGAGACAATGGTGTCTTCCCAGT TGGCTGGAGTAAATGGTGCCATTGACTTCAGTGCTTCCTCAATGAGCTCCAATCCCTTTC TCTTGGGATTTGTCATAGATATAACTCTCTCTTCTAACTGCAACTTCGTTGTTCCTAGCA CTTTCCCCTGGCTTTGTCCACTTCCTGGAAGCCCCACCACCTTTGCCAATGACTGGTCCC TAAATACAATGCTTTCTTCCCCATTGGCCAAAAATGGAGTCGTTTCCATCAGCGATACTG CCATGAAAGCCAGTCTCTGGATTGTTCTGTAGAGATAGTGGTCTCTTCCACAAATATTTC AGCCATGGTCTCTTGGGGATATGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTCCATAAGAATCTTGATCCTTTCTCCTATGTTTGGCAACTGCAATCAATGAT GCCTTCACTATTGGCCAGGAACAGAGGAAACTTCAGCTCAGTCCTCTCCAAGTAATCCCT ACTGTCTTCTCCCTGGATTGGACCCTCGAGAACTCTTTTTTTTTTTTTTTTGAGACAGGG TCTCGCTCTGTCCCCCAAGCTGGAATGCAGTGGCACAATCTTGGCTCACTGCAGCCTCTG CCTCCCAGTTCAAGCAATTCTCCCACCTCAGCCTCCCGAGTAGCTGTGATTACAGGTGTG CACCACCACACCCAGCTAGTTTTTGTATTTTTAGTAGAGACAGGGATTCACCATGTTGGC CAGGCTGGTCTGGAACGCCTGACTTCAAGTGATCTACCGCCTCGGCCTCCCAAAGTGCCG GGATTGCAGGTGTGAGCCACCAAGCCTGTCTGGGATTTCATTCTTTCCCCTCTTCTGTCA GTGTTTTGACCACTACCCTTAGACACCATGTCTGTCTGTACATGGAAGCCCCAAGCCCTG TCCTGACTGGTCTCAGGGGACAATGCTTTTACCCCCATTGGCTACAGGGGACCAATCATG CCAAAGAACTGGTAAAACGCTGGGACAGCAGGAAAAGGGACGTTGTGGACATCTCAGATG CAAGGCTGTTCTCATTCTCCCTGTCTAGGGCGATTCTGGAGGCCCCCTGGTGTGTGATGG TGCACTCCAGGGCATCACATCCTGGGGCTCAGACCCCTGTGGGAGGTCCGACAAACCTGG CGTCTATACCAACATCTGCCGCTACCTGGACTGGATCAAGAAGATCATAGGCAGCAAGGG CTGATTCTAGGATAAGCACTAGATCTCCCTTAATAAACTCACAACTCTCTGGTTC OMIM ID 605644