Entrez gene ID | | 11222 |
Official gene symbol | | MRPL3 |
Full name | | mitochondrial ribosomal protein L3 |
Aliases | | ,MRL3,RPML3, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q21-q23 |
Gene position | | 131221829 - 131181045 Map Viewer |
Gene orientation | | minus |
Gene size | | 40785 bp |
Gene sequence |
| |
OMIM ID | | 607118 |
|