Entrez gene ID | | 11251 |
Official gene symbol | | PTGDR2 |
Full name | | G protein-coupled receptor 44 |
Aliases | | ,CD294,CRTH2,DL1R,DP2,GPR44, |
Gene summary | | This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthama susceptibility. |
Location | | Chromosome: 11 Locus: 11q12-q13.3 |
Gene position | | 60623444 - 60618398 Map Viewer |
Gene orientation | | minus |
Gene size | | 5047 bp |
Gene sequence |
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OMIM ID | | 604837 |