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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HOGA1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 112817 Official gene symbol HOGA1 Full name dihydrodipicolinate synthase-like, mitochondrial Aliases ,C10orf65,DHDPS2,DHDPSL,HP3,NPL2, Gene summary The authors of PMID:20797690 cloned this gene while searching for genes in a region of chromosome 10 linked to primary hyperoxalurea type III. They noted that even though the encoded protein has been described as a mitochondrial dihydrodipicolinate synthase-like enzyme, it shares little homology with E. coli dihydrodipicolinate synthase (Dhdps), particularly in the putative substrate-binding region. Moreover, neither lysine biosynthesis nor sialic acid metabolism, for which Dhdps is responsible, occurs in vertebrate mitochondria. They propose that this gene encodes mitochondrial 4-hydroxyl-2-oxoglutarate aldolase (EC 4.1.3.16), which catalyzes the final step in the metabolic pathway of hydroxyproline, releasing glyoxylate and pyruvate. This gene is predominantly expressed in the liver and kidney, and mutations in this gene are found in patients with primary hyperoxalurea type III. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq] Location Chromosome: 10   Locus: 10q24.2 Gene position 99344102 - 99372559  Map Viewer Gene orientation plus Gene size 28458 bp Gene sequence >DHDPSL:50148566..50177023:Length=28458 CTGGGCTTCTGGCTTCAGAGCTGGGAATTGTGGGAGGAGGGCCCAGATCCCACTGGAGAT ACCGAAGGAGATACTCTTTAGTATTGGGATCCCAGAAACCAGTCCTATATCTGGCCAGAG GGACACTGGGTTGTGGCATCTCTCTAGCTGCTACCCAGAAGGAACAGGGCCCCCTGGGGC CTATAGGCCTTGCCCCTGACCCTGGGAACACCCAGCTCAGGCCTGCCCCAGTGGCCACAA GTCAGGGAGGCCGCAAATTTTTAACTAGAAACATTGATCATTAATAGGGGGTTAGAAAGA GTTCAAACTAAGTCTCACTCTGGGACATAGACCAATTGTGCTTCAGGCCTCCTGCAGAGA TGCTGGGTCCCCAAGTCTGGTCTTCTGTGAGGCAGGGGCTAAGCAGGAGCTTGTCCAGGA ATGTGGGGGTCTGGGCCTCAGGGGAGGGGAAGAAGGTGGACATTGCGGGTATCTACCCCC CTGTGACCACCCCCTTCACTGCCACTGCAGAGGTGGACTATGGGAAACTGGAGGAGAATC TGCACAAACTGGGCACCTTCCCCTTCCGAGGTAAGTGGGGCTGTCCTCTGTGGGACCTGG GGAGATGTGAGTGGCCCTTTAGCCAGAGACCAAGGGAGGGTACACAGGCTCTGTCAAGCT GTCCAGGGATAGTCTGGTACTCAGTGGGTCATTTTATTATGGGAGAGGAACAGGGGAGAC TGGTCTGGAGTCAGGAGACAGGCAGGAAGCTCCACGCTGGCCTGTAACCTTAAGCTAAAC CTCACCTGCTTCAGTTTACCCAGCTGTAAACTGTTAAAGTGCCTTTGTAGCTCCCAGAGT GATTCTGAGGTTGGACTGGATAATGGGCGTGAAAGTCCTTGTCAACCTTGTCACTTGGTG CAGATGTGAAGGCATGTGGCTGGGGTCACGTGGCAGCCCAGCCACAGTCCCAGTTCCCTC CAAAGTTTGTTTGTACATTCTCTTCTGGACAAAGCCTCCTTGCCAGAATTAGTTCTCCTG TGACCCCTTGGCTCCTGTGACTCCTGTTGTGGCTCCTGTGACCCCATCTCTCTTTACACA TGGGTCTCCCCAACTCTGAGGTTAGGGACCAGATGATATTTGCAACAATCAACATGTAAC AGAGTCCCAGGCACAATAAATGAAGGTAGAAGAAAATGTCAAATTCTGCCTGCCCTGCTC CGCCCATCCCCATTCCTTACTGCACAATCCCCTGAGGCAGTGCTCTCTGTAGGACCATCC CACAGATGGGAATCTGGGCCTCAGAGTGACATGGTCACTGCCCAAGGTCATTCGGCTAAC ACATAGCTGAGCTGAGGTTTGCACCTCGTCTGACTGCATGGCCCATGCTCCATTTTACTC CCTCGCTGACTCTCATTATAAACCCTTTGGAGCTGCTAGGCCACACTATTTCAACGGAGT GTCTGGTCAGCACTAGCTTTGTTGTGGCTGCTATTGAGGCAGTATCGTGTAGACTGTGGA CTCTGGTTTCAAATCACAGCTCTGGAGTGAGCGCCTGTAATCCCAACACTTTGGGAGGCC GAGGCGGAGGGATCATGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATAGTGAAACCC CGTCTCTACTAAAAATGCAAAAATTAGCTGGGCGTGGTGGTGTGTGCCTGTAATCCCAGC TACTCGGGAGACTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGATTGCAGTGAGC TGAGATCATACCATTGCACTCTAGCCCGGGCGACAGAGCAAGACTCCATCTCAAAAAAAA AAAAAAAAATCAAATCACATCTCTGGCACTGACTTAGTGTGGGATGATTGCTGTCCCTAT CGGACACATGGGAGTGATAATGCTCATATTATGGGATGGTTGGACAAAAAAATCTGAGAG AATGCAAGTGAAATCGTGCTATAAATTGTGGAGTAATATACATTGGAAGGTACTGATTCC AATGGTAATAATGATTAAAATGACAGTGTGATTGGCATTGCAGCAAAGCTGCTTTGTGAC TGTGACCCCTGGCCTGATGGACACGTTGATCATTCATAGCTCAGTACTGAGGGAATGTGC CCCTTCCTTGGGGACAATGAATGCCCTGTGGAGGGCCACGTTGAGCAGGGCACAACTGTT AGGTTTCTGCTGGTGCTTGGCTCGTGGGGCCTGGAGGTTTGGTGAGGTCCTGGTTCTCTT GAAGTGAGAAGCATTTTGAGCCTCTAAGTGAAGACCTTACTTCAGCTTCAAGGTTCAAGG ATGCTCTAGTTCAGGGTGGGGAGGGTGGACTTTGCATCTGGTGTTTGCCTGACACCCAGA GAATCCACAGAGACCCCCAGACTCTTCTCTGGACCCTCCCTTCTGGGCCACCCACCCACT CTTGCAGAGGGCATGGGGTGCCCAGGAGCACAGGCTTCCGTGGATTTAGCAGGCTGTGGG CTGCACATACCCACTTGTCTGTCTCCCTCGCAACCTATGCAGGCTCCAGCTCCCATCTGA TCACTCACCCACACACCAGAGAGCCAGCGGGGTGTGGTAGGAAGAGCCCAGCATCTTGAG TTAGAGGACCTGGGCAAGAATCCTGCCACTTCTGCCAGTTAACAGAGACCTTGGGGAAAC CACTTAACCTTTCAAATCCAGTCCTCATTTTAGAATAGGAACTGAGCCTTCAGGCTTCTA GCCACAGGGTCAATATAATCCTCCCAAGGCACTGTCACAGAAAACACAGAGATAGAGGGT CCCTTCCCTGCTTCCAGGGTGCAGCCAAAATGCCCAGGAAGGAAGACACAAACAACTTTA GCTCTGAAATCTGTGTTTCTCTTGCCCTGTCCTGGCCCCTGAGGTAGACTTTGCAGCCCA ACACTCAGGCTGAGGAGGGAACGTATCACATTGTAAGGGCCTCCTGCAGCCAGTTAAAGG TCCTCTGAAGAGGAGATGAGGGCCAGGCACAGTGGCTTACTCCTGTAATCCCAGCACTTT GGGAGGCCAAGGCAGGAGGATCTCTTGAGACCAGGAGTTGGAGACCAGCCTGGCCAACAT AGTGAGACCCTGTCTCTATTAAAACAAATAAATAGGAGGTGGAAAGCTGCCCTGGATGAA TCAGTGAAGAGTTAGAGATTCTTCTGGAAAGCACTCCCTGAAACTGTGTAGCTTTTTTTT TTGAGACAGAGTCTTGCTCTGTCGCTCAGGCTGGAGTGCAGTGGCATGATTTGCCTCACT GAAACCTCCGCTTCCTGGGTTCAAGCGATTCTCATGCCTCAGCCTCCTGAGTAGCTGGGA TTACAGGTGCCTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTC ACCATGTTGGCCAAGCTGGTCTTGAACTCCTGACCTCACGGTCCGCCGGCCTCGGCCTCC CAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCTGGGCCTCTTATTTATTTATTTATT TTTAAGATGGGGTCTCAGTCTGCCACCCAGGCTGGACTGCAGTGGCACGATCTCGGCTCA CTGCAACCTCTGCCTCCTGGGACTAAAGCAATCTGCCCATCTCAGCCTCCCGAGTAGCTG GGACCAAAGGTGCACACCACTATACCCGGCTAATTTTTTGTATTTTTAGTAGAGATGGGA TTTTGCCGTGTTGCCCAGGCTGATCTCGAATTCCTGAGCTCAAGTGATCTGCCTGCCTCT GCCTCCCAAAATGCTGGGATTACAGGCATGAGCCACCATGCCCGGCCCCGTGTAGCTCTT TTTAAAAAATCTTTTTAGCATTGCTAATTTGTACTGATTATTTGAATAGAGAGTATTCTT TTTGTTTTTTCTTTCTTTTTTTTTTTTTTTTGTGATGGAGTCTTGCTCTGTCTCCCAGGC TGCAGTGCAGTGGCACGATCTCGGCTTACTGCAAGCTCTGCCTTCCAGGTTCACGCCATT TTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCTCCCACCACCATGCACGGCTAA TTTTTTGTGTGTGTGTGTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGAT GGTCTCAATCTCCTGACCTCGTGATCGTCCGCCTCGGCCTCCCAAAGTGTTGGGATTACA GGCGTGAGCCACAGCGCCCAGCCAAGAGTATTCTTTTTAAATAAAAATTATGACCAGAGA CTAGAGGAAGGGGTCATTACAGAAGGGCTCTATGGCCCTGAACTCACACCCATAAACACC CTCAAAGATGGACTTTGAATTGTTATTTCCAAATGAGGTTAGCCAACCACAGAACTAGTC CAGCAGGACTGGGAAGATGAGGTTCTCCATAAAACACTTGTGTCCTATTCCTTCCATACA TAGAGTGGACCATGCTTTCTTGCAAAGATATAATATTTTGTATATATTAAAACCATTACT CTGTTAAAGAAAATATTTTGTTTAAAGCATCACAATGTTTACAACCCCATTTTGGCATTT CTTATTTTTTTTTAAATGGGCTAGATGCTTTTGAGGGGAAAAAAAAATACAGTGGCCCAG GCCTGTTTATACCCTGAGAGGCCTTGGAGATTAATTAGGCTTTTAGTTGTCTGCACCTAT GGAAAGCCTGGCCAGCCAGCCCACCTGCTCACAACCCGAACCATGCCTATTTATGGGGGG GCAAATTCTGGGTTTGTAGGTGCCTCACTAAGGCAAGAGGTAGCAGCTACCATCCCGGAG TGGCCCCAGGGATCTAGACCCGATGAAGTCTCCTGTCCACTCTGCCTTCTCAGCCCACTG CTTGCCTCTCCACCCTCAGCCCATTGTGACCTCATGTTAGTTACTCCAGAATGAGCTCCT TCCTGGGTTCTTTTCCCTCTGAACTCTGCCCTGTAGTGAGGCGAGGGGCTGCAAATGAGG ATGGAATATGCCAGGCTGGCAGCAGACATGGGCACTGGATGGAGGTGCACTGGTCTCAGA TGGCTAGGAATGGATACCAGCCCAGTCAAGGGGATCATTCTGTCATGGCCAGCCTGACCC AGCATACTTTGCCCCCTGGGGGCCACCAGATGGGGAGAGAGAGAAACCAAAGACTGGAAG ATACAAAGGCCTAAGTTGTAGAATGGATTCCAAGCAGAAGGCAGAAGGACTCAGAATTGG AGAAGCAGCCCTTTCACTGAGCCTGGGGACAGCTGTCAGGGTAGGAGACAGGACCCAGGC CTCAGGCAATGCCTGCCAGGCTAGACATGAGGGATGCTGCGGCCTCTCCCCACCCCACTC TCCCCACCCCACCCGCAACTGCCTTCCTCACAATGGGGTTCATTGTTGAGGTGGTGGGGG GCACCTAGGGAGGGTGCAGCAGGGGGCCTGCCTGTCAGACATCCTTGGGGAGCCTGCCCT TTCAAGCATGAATCATACCACCAGAGATCACCCAGCGTGCTCTTAGCTCTGCCTGCCTGG TGTAGGGTCCTGGAGACCTTCTTGGAGCTCATCCAGCAGCCATCATGCAAGGTGGTGCTG GGGACTGCCCTCTTGCTAGGAGGTGGAGGTCTCATGCTGTGGGTTCAGAGAAAGAGGAGA AGAAAGGAAACCTCTGAGTGTCCATCAGACAAGGACAAGTCACCAGAATCCCATAAAGCA AAGAATGAAAGCTGGATTAAATCCCACTTTAGCCGCCTTTCCGAAGAGAAGCTGGCCCTC GACAACAATGCCAGCGCTAGTGGCAATGCTACCCAGACTGAGAGTGGGAGTGAAGAGGTC AGCTCCACGGTTCACATAGAGACCTTCACCACGAGGCACGGAGAAGTGGGCTCCGCTCTG CACCGGGAATCCTTCACCAGCAGGCAGAAGACATCTGGGCCCTCAGTGATCCAAGAGATC CACCAGGAGTCTGGAAAAGCCCCATCCACTGATGAGGCCACGTGGGCCGCTGTGGCTGCC TGCACCAAGGAGATTGACACCCAGGGGCGGCACCTGGCTCACTCCATGCTGCAGCGGGCC ATAGCTTACCAGCACTCAGGTCACCTAGAGTCCAAGGACATCAACCAGGAGGAGCTGAGG GCCCTCGAGGAGGTAGAGATGAAGCTGCAAAAGAATTTCCTCACCCAGCGGGAAAACACC ATAGCTGGTGCCAATCACACACACACCTTCTATGGCCACAGTCACCACAGTCACCATGGC CACCCAAGCCACCAGAGCCACAGCCTGCCTAATCGCAGACACTAGATCTGTGACTTCTTG GAAGCCACCTAACCATGGATGGAGACGCCCCTGCCCCCAGCAAGGCTGGCTCACACACAC GTCTGTTTTCTCTCCTATGGGGCCATCTATGCAGGCCAGGGTGAGATGCTGTGCCCAAAT CCCTACTTTCTTAGGCTCCTCACGGGGATTATGGGCTCTTTAAACTCCATGAGTGGGGTC TGCCACAGAAGATGGCCCCTGTTGGAGGGAGAGCTGGGAGGACACAGCGCAGGTGAGATA GACCCTGAGGCCCCTGAAGACCCACCAAGAGAAGACAGATGGGAGCAGGCAAGAGCCCCA CACTGATGTCATTGCCTGGAACGGAGCCAATAAAGCTTTGTGTGCCTTCACTCTGAGTCC AGGGGCTCTGTGGGCAGCCTAAGGTCTGGCAGGGATGGAGGGAGGGGGCTCCCTCTCCAG CAGTCCTCTGGAGTGGAGTGGAGAAAAGGCCCCCGACCTGGGGCCTTTTCACTGGGCCTC ATTTAAAGCTCCATAAAACAGCTACCCTGGTCTCAGGTTCTGGAAAAGGGGTACCTCTAG ACGTCTCAACACCCCCAATCTGATGTTGCCAGGGAAGAGGGGAGCAGCCAGGTATTGGGC TTGGAGGAGAAACAGGCTTTCAGAGGAGAGTAACTAAGCCAGGTGGGAATGAGGGCCCCT GTCGTCTTGGTGCTATCTTTGCTCTCAAGTCATGTGGCATCCTACAAGGCAGTTCTCTCA CCAGCCCCACCTGCTTCCTGGGGCCCCTTGGGATCCATGTTAGTACCTCCCCACCACCTA AGTCTACAGCTACTGAGTGAGCACAACACTTTCTTCTTGTTTGTTTAACTTAATTTAATT TAATTTAATTTAATTTAATTTTAAGTTCTGAGTTACATGGGCAGGATGTTCAGGTTTGTT ACATAGGTAAACGTGTGCCATGGTGGTTTGCTGCACCTATCAACACGTCACCTAAGGTAT TTATTTAGCCCTGCGTGCATTAGCTATTTAACCTGATCATCTTGGGTTCTTTTTTTTCTT TTCCCTTTTTTTCTTGTTTTTTATGTATGTATATTTTGAGACAGGGTTTCACTCCTGCTG CCTAGGCTGGAGTGCAGAGGCGTGATCACGGCTCACTGCAACCTCTGCCTCTTGGGTTCG AGCGATCCTCCCACCTCAGCTTCCCAAGTAGCTGGGACTGCAGGTGTGTGGAACCACACC TGGCTAATTTTTTTTTTTTCTTTTCTTTCATTTTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGACAGAGTCTCGCTTCATTGCCCAGGCTGGAGTACAGTGGCGCGAT CTTGGCTCACTGCAACCTCTGCCTCCCGGGTTCATGCGGTTCTCATGCCTCAGCCTCCCG AGTAGCTAAGGCCAAAGGCACACACCACCATGCCTGGCAAATTTTTTTTGTATTTTTAGT AGAGATGGGGTTTTGCCATGTTGCCCAGGCTGGATTACAGTGGTGATATCATAGTTCACT GCAGCCTCAGACTCAAACTGGCAAAATTCAAATAAAGTCCTTAGTTAATGACATTGTACC AGTGTTAATTCTTTGGTTCTGGTCATCATATTATAGCTAGGTAAGACATTATCATTGGTG GAGGCTGGGTGAAGGATGTATAGAAAATCCCTGTACTTTTTTTTTTTTTTTTTTGAGACG GAGTCTTGCTCTGTGGCCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCATTGCAAGCT TCACCTCCCGGGTTCATGCCATTCTCCTGCCTCAGTCTCTCGAGTAGCTGGGACTACAGG CGCCCGCCACCACGCCTGGCTAATTTTTTCCATTTTTAGTAGAGACGGGGTTTCACTGTG TTAGCCAGGATGTTCTCCATCTCCTGACTTCGTGATCCGCCAGCCTCGGCCTCCCAAAGT GCTGAGATTACAGGTGGGAGCCACCGTGCCCAGCCAGAAAATCCCTGTACTATTTTTGAA ACTTTTCTGTAAATCTAAAAGTAATTCAATATTTCAAGTTAAAAAAAAAGTTTTCAGACA ATTTGATTATGAGTGTGTGTCAAAGTTTGATTATCGTTGTAATGCAAGCAAAATGACCTG TAAGCAGCTAACTCAAATATATACTCTTGGTAAGAATATTTTTATTAAAAAAAGAATGGT CAGGCTGGGCGTGGTGACTCCTGTCTGTAATCCCTGCACTTTGGGAGGCCGAGATGGGCA GATCACTTGAGGTCAGGAGTTTGTGAGACCAGCCTGGACAACCTCGTGAAACCTCGTCTC TACTAAATATGCAAAAATGAGCTGGGCATGGTGGTGCCCACCTTAATCCCAGCTGCTTGG GAGGCTGAGTTGGGAGGATTGCTTGAATCCAGGAGGCGGAGGTTGCAGTGAACAGTGATC GCTCCACTGCACTTTAGCCTGGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAA AAAAAAAGAGAATGGTCAGATCACTCACTGTTAAGACTACGTAAAGACAAAGAAGAGTAG TTAACAGCTTCTAGGCTCTTGCCTGAGAGTTGGCTGGGAGGGTGGCTAATTTTCCAGATC AAGTCTTAATTCCATTAAAGTTCATTGGGGGCCGAACACGGCGGCTCACGCCTGTAATCC CAGCACTTTGGGAGGCTGAGGCAGGTGGGTCATCTGAGATCAGGAGTTTGAGACCAGCCT GGCCAACATGGTGAAATCCCATCTCTACTAAAAATACAAAAAATTAGCTGGGTGTGGTGG CAGGCACCTGTAATCTCAGCTACTCGGGAGGCTGAGACAGAAGAATTGCTTGAACCTGGG AGGTGGAGGTTGCAGTGAGCCGAGACCATGCCACTGCCCTCCAGCCTGGGTAACAGAGCC AGACTCTGTCTCAAAAAAAACATAAAAAAGAAAAAAATAAATAAAGTTCATCACAAAAAT GCTTAAGCATTTCATCAGGAATGTAATTTCTTTCCAGAGGGAGGTTATGAATTATGTCAT GCAAAAAACTTTGGCCGCAGACCAGGGCAGAAAAAAATAAAGAACTTCTTTTTCTTTTGC ACAACAAATTGTCAACACACACCTCAACACCTATGCTAGGCACCACACAGGAGGCCAGAA TGCATCCAGGCAAAGTAAGGCAAGCACTGGGCAAGGAAAACAGAATGCTGGGTAGCCGAC TTGAGCTTGTTGGCCCGCATTTGGAAGGTGTTCCAGGCAGAAGGGAACAACACAAGCAAG GGTGCAGAGGGAGGGAAGTGCAGTGTCTGGGGAACCATGGCAGTCAACTTGTTTTTTTTT TGAGACCGAGTTTCACTCTTGTCACCCAGGCTTGAGTGCAGTGGCACGACCTCGGCTCAC TGTAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAATAGCTGGG ATTACAAGCGTGCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGCGTTT CACCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATTGGCCTGCCTTGGCC TCCCAAAGTGCTGGAATTACAGGCATGAGCCACTGCGCCTGGTCTTTTTTTTTTTTTTTT TTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAGGCTACCGATCAGTGGTGCGATCTG GGCTCACTGCAACCTCCACCTCCCAGGCTTAAGCAATTCTCCTGCTTCTGACTCCCGAGT AGCTGGGATTACAGGTGCGCGCCTCCATGCTTGGCTAATTTTTGATTTTTAATTTTTTTT ATTTTTTTAAGACAGAGTCTTACACTGTCACCCAGGCTGCAGTGCAGTAGCCCAATCTTG GCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCGGCCTCCTGAGTA ACTGGGATTACAGGTGCCTGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACG GGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTTGTGGTTCGCCCGCCTC GGCGTCCCAAAGTGCTGGGATCACAAGTGTGAACCATTGTGCCTGGCCTAATTTTAATTT TTTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTC AAATAGTCCACCCGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGC CTGGCCCAATTTCTTATTTTATAGGAGAGGTCAGATTGAAAAATTGTGTCTAATCCCACA CATGGGGGTGGGGGTGGAGGATTGAAGAGTTCTAGGGACCTTTGTAGATGGGTGCTGTCC ATGGGGAAATATTATACAAGGAACAGGTAACGGAAATGCAGAGCAGGGAGGCCCAGTGGA GAGATCCCAGGAAGACTTCTCAGAGGAGGTGGCAATGATGATGGACTAAGAACGCATAAT AATGTCTGGGGACACTCCTTATGTGATTCTTTTTAGCCACAGTAAGTCACCATGTTGCTT ATGTGTCCCCAGCCCCAAACGCCCACTCCCCTCACTGCCACCCCAGCTCCCAGAGCAGCA AGTGTAATCATGGGGGCAGGGGAGAGTATCTTCCTTTGTCTTACAGCTGGAGGGGGCCTT GTACACCCACTCCTAATATCACAGTAGGTGTACAATGAGAGGTCATTGAGAGCAGCCTCC CCTTCAACACCAGCCACCCTCCTGATTTAAGGTTTGAGCACTTTCTCCTGACTCCATAAG AATGACAGCTAACACTTATTGAGCACCAGGTTCTATTCGAAGTACTTTATAAATAGTATC TCATTTAAACTTCAAAACAACTCTGAGAGGCTGGGTGTGATGGCTCATGCCCATAATCCC CAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGCCAGGAGTTCGAGACCAGCCT GGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGCATGGTGTCA GGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGATAATTGCTTGAGCCTGGGAG ACAGAGGCTGCAGTGAGCCGAGGTCGCACCACTGCACTCCAGCCTGGGCAACAGAGTGAG ACTCTGTCTCAAAACAAAACAAAACAAAACTCTGAGAAAGGCACTAATATCATCACTATT TTTTAATTGAGTTAGCCTGGGCTTCTCTGACTTCAGGGCCTGTGCATCTGACCCCTCTTC TGTGAGCCCTCTGCTTTTCTGCTTTTTCCCCAGTCCCTGCTTCATTGGAGATCCTGGCCT TTTCCTCTCCTCTGGCCCCCTCTCTACACTAACAGGGACACATCAGGCTCACACCTGGAC ATCTAACCAGGGTGAAGGAGGGGCTCTTTGGGGTACCCACTCACAGATTTCTGGGACATT TTCTTATCCTTTAAAACAGTCCTATAAGCTAGGATTGAAATGATTTCACTGTCATCCCAT AGAAAAGGAAACAGACTCAAAGATGTGATGTGACTTGTTCAATATCCAGAGGTGACTCTT GAGTCTAGTGCTGCCCTGACTACGCCACACTCCCTCTTCTCCAGCCAGGCACTTCTTCCT TCTTGGGAGTCAGGCATGAGTCAGTTGCCCCCTTCAATGAGACAGAAGAGAGGGCTGTGT CATAGAAGCTTTGAGCACAGTGTCTGCTTCTGACTCCCAGAGTGCAAGCCTCAGCTGTCC TGCTGTTTAGACCAGCTCCACCTGTAGGGCCCCTGGAACTGACCAGCAGGATGAGAGGTG AAGGAAGAGGGTGATGGTGGCTGAATCAGTGGCCGCAGCAAGAACCTGCCCCAGCCCAGG ACGGCAGGCAGGGTTGGGGAGGAAGATGACTTTGGTATTGGAACAGAGAGAGTGGCAAGA GTTTGATCTTTGACTCTTTAGTCAGAGGGTGCTGGTCCAATCGTAGCTAGATTGGAGTCC TCACCCAGGGCTGGCAGCTTTTACGGAGAGCACTGCAGCCCCATGTAGCAAGACACAGGG AGGCCCTTCCTTGGGCTGCTAGCCTGACACACAGGAATCAATCCCCCAGAAGCAATCCCA CAGGAGCGAGAAGCTGTGTGCCTCCAGACGTTCCCTGCAATGTTACCAATGCAAAATAAC TACCAAAAAAAAAAAAAAAAAAGCAGCTAAATATCCAATGAGAGATATCCTGATATCCTG GCAACTCACTCTGGAATCTGACGGTGTAGTGAACAGCATGGAAAAAGTTGGTGGAATGAA GTGGAGTCTACATCACACAGTGTCCCCTGAAGGATGACTCACAGGAACAATTTCTCTTGG TCCCAGTGCCAGGAAACTCTGTGTTTCTCCGGGGCAGTTGCTTTGCTTTTATCTTTTGGG TTCTACATGTCTGTTAGCTGACCATGTTTCCCTTTTAGCTCTGGCTATCAGGAAACTCCA CATCGAATTTCTGGCTCATTTCTCACAACTATATGGCAGGAACTTTGTATACCAATACTG CTTGTGGCCTTATTTTCATTTCCTTCTCCCAAATAGCCTCCAATTTTTTTTTTTTTTTTG AGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCATAGTTCACTGC AGCTTCAAATGCACCTGGTTTATTTATTTTTTATTTTTTTGTAAAGTCAGGGTCTCACTT TGTTACCCAAGGTGGTCTCGAACTTCTGGCCTCAAGTGATCCCCCCATCTTAGCCTCCTG AAGTGCTGGGATTACAGGCCCAAATATCCTTCTATTAATTAAGAATCCTGTTGTATTGTA CTCTGTGTTTGTAAACTACTGCCATTTTTTTTTTCTTTAATGGAGTGGGATAGAGAGGAG AAAGAAGAAGAAAGAGAAAGTTAAGCGGGCTGGGCACTGTGGCTCACCTGTAACTGGTAC AGGTATACTGGTTAGACATATCCCAAGTAAGTGATTGATAAAAACAGGAAAACGCAAAAT AAAGCAATGAGATTCACTTTTCACCCAGAAAGTTGGCAAAAATTTGTTCTGACAATACCA TGATTTGGCATGTATGACATTCTATGCTGCTCCTGAGGTCTACACTGATTGATTAGAAAT GTGGCGCACAGTCAGGCATGGGGGCTCATGACTGTAATCCCAGCACTTCTGGAGGCTAAG GTGGGAGGATCACCTGGGCCCAGGAATTCGAGCCAGCCTGGGCAAAATAGTGAAACTCCA TCTCTACAAAAAAAACTACACAAATTAGTTGGGCATGGTAGCTCATGCCTGTAATCCTAG CTGGCTAAGACAGGAGGATCACTTGAACCTGGGGGGCTAAGGCTGCCGTGAGCCGTGATT GTGACACTGCACTCCAGCCTGGGTGACAGAGTGAGACCCTCAAAGAAAAAGTAAATACAT AAAAAATGTGTCACAGATGAAGGTGCACATAGCTATGACTCAGCAATTAACACACCAAAG TATCTGAACTCTAGAGGAACTCTTAGACATATGCACAGAAGACTTTACAGAAAATGTTTG TTTCAGCATTGTTTGCAATAGCAAATAGAAGAAAACATTCTTTTCTTCTTTTTTCTTTTT TGGTAGAGACAGGTAGGCCATTTTTTGGTAGAGACAGGCAGCCATGCTGCCCTGCCTGGT TTTGAACTCCTGGGCTCAAGCGATCCACCCACCTTGGCCTCCTAAAGTGCTGAAATTATA GGTGTGAGCCACCAGGCCCAGCCAAAAGAAGGAAACATTCTAAATGCTCTCAACAAGAGA ATGACAAATAAATTGTGTTCTAACCTTACAACAGAATACTATACAGCAATTAAAATGAAT GAATCAGGGCTACGTGTGCTTTTATGAACAAAGCTCAAAAAATAGTATTAAACAAACAGC AAACTGCAGAAGGCTATTTAAGCTTAATTCCATTTCTACAAGGCTTAAAATTGTAATAAC CTTATTACATAAGGATCACTTGAGCCCAGAAGGTCGAAACTGCAGCAAGCTATGGTTGAG CCACTGCATCCCAGCCTGGGCAACAGAGTGAGACCCTGTGTCTAAAAAAGAAAAATGATG TGAACAGTCATTGCAGCTGTGTGGGAACCTTCTGTCTGCAAAGATGGGAAGGAAATGTGT GAAAGATTATGGTGTCGTAAGGTAGGAACACCAATGTCCTAGTTGTTCGGTAGAGGATGG GAAGGAGTTAGTCAGCTGTGTCTCTTGCAGGCTTCGTGGTCCAGGGCTCCAATGGCGAGT TTCCTTTCCTGACCAGCAGTGAGCGCCTCGAGGTGGTGAGCCGTGTGCGCCAGGCCATGC CCAAGAACAGGCTCCTGCTAGCTGGCTCCGGATGCGAGTGTGAGCCAGAATGCCCTGGGC CCTGGGGGTGGGTGGATGTGCAGGATCCAGGCTCCTAGGCCCTAGCTTGGGTCCTGTCTC CTTGTTCTGCCTCTTCTGGGACATGCTGAGGCACCTTCGCTTGGCCCAGTGTCCTGGTCC AGGCCTCCTTCTGCCTGCTCTCACCTCTCTCCTTCCTCTGGCAGCCACTCAAGCCACAGT GGAGATGACCGTCAGCATGGCCCAGGTCGGGGCTGACGCGGCCATGGTGGTGACCCCTTG CTACTATCGTGGCCGCATGAGCAGTGCGGCCCTCATTCACCACTACACCAAGGTGTGTGT GAGGCCTGAGACCAAGAGGAGGCTCTGCCCAGGGAGAGGAGATAAGGGAAGCTGGGAATA GGGTGGTGCTTCACATGAACGGCAGCTATAGGAAACGGGTGGACTGCCACCATGGATCAG CTGCACGACATTGGGAGGCTTACCTGACCACTCTGTGTTACTGCTTTCTCCCCTCTAAAA TTGGAGGAATGATGTCATCTGTCTCATAGGGTTGCAGTGAGCATTAAATGAGATCAGGAA CATAAAGGCCTTAGAACTGTGCGTGGCATATGGAAAGCACTCCATAAATATGACCCACTG TGATTGCTTACACTCGGGGCACGTAGCATGGGAGGGAGGCCTGTCCAGGTGGCCCTGTAG TGAAGCAGGCTGGGACCTGTGGGTGGGCAAGTCTCTGGCTCTTGGGACCTGGGGCGGCTG CCCTCTCCTGCTTTTCTCTGCGCCCCCCTCCCCAGGTTGCTGATCTCTCTCCAATCCCTG TGGTGCTGTACAGTGTCCCAGCCAACACAGGGCTGGACCTGCCTGTGGATGCAGTGGTCA CGCTTTCCCAGCACCCGAATATTGTGGGCATGAAGGACAGCGGTGGTGATGTGAGTGGCA GCAGCTCCGGGGCTGGGGTCCTCTCCTCCTTTTCTGGGTCCTAGCACTTTTGCTCCTGAG GGCAGCTCTGAGATCTGTTTCCAACCTTGGCTTCTGTGTGGATTCTCTCTGTCGTGCGGG CTCTCTGGGACTTTCTTGAGGGCATCTCTTTGAGCACTGGGCTTTCATTCCACCACACTT ACCCGGCCCTCATCCAGGATGAGGCTCTGGGCACAGCTCTCACACCACATTTGCTGTTGC AGGTGACCAGGATTGGGCTGATTGTTCACAAGACCAGGAAGCAGGATTTTCAGGTGTTGG CTGGATCGGCTGGCTTTCTGATGGCCAGCTATGCCTTGGGTAGGCCGCCCACTGCTCTCA AATTGTCATGGGTGACCAAGAGATACCCAGGTACCTGGGTCTTCCGGGAGAGATCGTGAG GGCTGGGGCTGGGTCTGCAGATGGTAGTTTGCCAGCCTGCCCACTCTGAAAACTCAGAAA CCTGGCCACGCCGCTTACCTGTCTGAATTCGGGATGCTGTGAGTAACCTTGTTGGCTGAA GGAGGATGGCCGTGTACAATCCCTGGCCTGTAGTAGGGATGCCTGCAGTTTGTTCTGAGT CCTGAGCTCCATGATTAGATGACAAACTTAGCTGCTCTAATCCCACCTTGTACATCATTC TCTGAGGGCAGAGGCCCTGGGGCCCTCCTCTGTAGTTCAGGAGTCCATTTTCCTCTCCCC TGTCCCAGACCAGAATGAATTGTCAGATCTACAGAGTTGAGCCAGGGATCTTCAGTTGCC TGATCAGATTCTGTTCCAATCCAGGATCCCTAGGAATGTCACTTAGATCAACTGCTCTTG TCTGTTTGGGGTCAGGGTCCTTGGGTTTGGATTAGATTTGAGCCCTGGAGGGAAGGGAGA AGAAGGGAAGCTGTTCCCTTCAGCTGAAGCCCCAGTGAGTAGAGATTTGAGGGACTTTTC CAGCACTGCAGGGGAGAATGCTTGTTCCTATTCCATCTGGTCCCTCCAGACTTTGGCTGG TTGTCTAGGCCTTTGTACATCTCCCCTGCCATGTCATGGCCTCTACGGTGAAGGGGAAGA AGAAGGGATCCATTTCTCCCTCATTCCTGGAAGTGGAGTAGATTAAAAATAAAAAAAAAA GCACAGGCTCTGGAGGCTGGGGGGAATCTCAGCTCTGCAGTTTATTCACTGAGTAATGCT GGGCAAAGCACTCACCTCTCTGGGCCTGAGTTTCTACTCTGTGTACAGAGGGATCATGAG GATTAGAGAGCATCAGGGCCATGCTGCTGTAGCGCGCCTGGGACACATAGTAGGTATTCC ACAAACAACAGCTCTATTAGCTCATTCTGAATTGCCTACTCTCTCTACGGTTTTGAGGCC ACTGTGCCTAGGGTTCCACTCCTATCTAGCCTTAGAAGCATACTTACAGGCTTGCAGAAG TGGCGGGGGTTTCTGAGATCACAGCCAAACCCATTTTCATTGCCCCGATGGGCACAAAGA GGACTAGAGAGGGTCTCATTCAGGTTTATGCAGTCAATGGGAAGACATGCCTGGTGACCT GACTCTGTCCAGAGTGCTTTCCATGCCCACTGCTGTCTCTGGTTGCATCCACTGGGGGGA ATAAAATTTCAAAAGAGCAAAGGCTTCCCATCCGTCCTACCCTCTTACAGGACTGATGAG TCAGGGGGCTATTGGAGGAAGCTGGAGGTGTCAACTGTCAGATGGGATTTTATTCCGGGA GGGGTTCAGGGAAGGAACCGTCCTTGAGTTCACTTTCAGGCTCTGCTCCCTGCCCCTCAC AGATCAGCCCTGAGCAGTGCTTGACCTGCGGGATTCTATTTTGAATATGCAGGCAGCTCT TCTCTCTGGAAATGTATACTCTGGACTCACAGAGCATGCCTTTGATGTAGCCAGCCAAGT GACATAGAAATCTGTATCTAATGTCCCCAGGCTGAAGAGGTGCTGGGACCAGGGCTTGGG ATGCCTGGAGGGGAGAGGCTCTGGCTGATGTTCTGCGTCTTACTTCGTGCAGGAGCTGTG GGGGGCGTCTGCGCCCTGGCCAATGTCCTGGGGGCTCAGGTGTGCCAGCTGGAGCGACTG TGCTGCACGGGGCAATGGGAAGATGCCCAGAAACTGCAGCACCGCCTCATTGAGCCAAAC GCTGCGGTGAGCCAGTGGCAGCGGGGGCGCGGCCTGGCGGGGGGTGGGCAGTCTGTGTCC TCATTGGAGCAGGACCCAGGGCTGGCACCAGGCCCCACTCAGTCTCTTCCTTTCAGAAAA TCCTTTGAGAGAACATCCCAGTGTGGGAACTCCTTGTGACTCCCAGAAAATCCTGACTTC GGACAAAGTCGAGCACCACTGATTGTCAAACTTAAGTGTGCATTAAAATTTCCTTGGGGG CGAATTAAAGTTCCAACTTTTGGGCCCAAGAAGATGCATTGAAACAAACATCCTGTGTGA TTGTGACAGAGTAACCCTAGGACCACACTTAGAGATGCCTGGAGAGAAAGAGTGTAAACC AGGGGCCTCTAAATCCGTGCTATCGGGGGCCAGGTCCTGAAAAAATAGGAATGACTGGGG CTGGCAAAGGAGTTAGAAGGCAGGAGAGTGTTGTCTTCAAATAATCGGTTCTGTGGTCAG ACTGTATACCCCAATTCTTTGTTGGGCAAGCAAAGGAGAACTTCAGAGAGAACGCCCATC AAGTTCAGGGTCATTCTGAAGTCTGAGGCAACAGAAAAATATGTGCCCCTGTATTCAAGT TTTAATGTACATTTTATCCTTTCTTTCCTTCGTTCCTTTGTTCCTTCCTTCCTCCCTCCC TCCCTCCTTTCTGTCTTTCTTTCTCTTTCTCTCTTTCTTTCTTTCCTTCTTTCTTTTTTT AGACAGAGTCTTGCTCTTTTGCCCAGGCTGGAGTGCAGCAATCTCAGCTCAGTGCAACCT CTGCCTCCCAGGTTCAAGCAATTCTTGTGCCTCACACTCCTGAATAACAGAGATTACACG TGTGCACCACCATGCCCAGCTAATTTTTGTTTTTGTTTTCATTTTTCAGTAGAGATGGGG TTTCACCATATTGGCTATGCTGGTCTCAAATTCCTGGCCTCAAGTGATCTGCCCACCTCA GCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCACAGTGCCCGGCCTATTCTTTTTTCT TTTCTTTTCTTTTTTGAGACATAGTCTCACTCTGTTTCCCAGGCTGGAGTGCAGTGGCAC AATCTTGGCCCACTGCAACCTCCGCCTCCCTGGTGCGAGCAATTCTCCTGTCTCAGCTTC CCTAGTAGCTGGGATTACAGGCACGTGCCACCATACCCGGATAATTTTTTTGTATTTTTA GTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTAACCTCAAGTGAT CCTCCTGCCTCGGCCTCCCAATCTTTTTTCTTTTATTTTTTTTATTTTCGAAACAGGGTC ATTCTCTGTCACCCAGGCTAGAGTACAGTGGTGTGATGACAGCTCACTGCAACCTCAATG TCCTGGGCTTAAGCAATCTTTTTAATTTTTTATTTTTATTTTTGTAGAGATGGGGGTCTC ACTATGTTGCCTAGGCTGGTCTTTATCTCCTGGGCTCAAGCAGTCCTCCCACCTCAGCCT CCCAAAATGCTGAGATTACAGGCATGAGCCACCATGACTGGCCTACTGTATATTTTATAT TTAACTTTTTATTTTATTTTATTTTATTTATTTATTTTGAGATGGAGTTTCACTCTGTGC CCAGGCTGGAGTGCAGTGGCACAATATTGGCTCACTGCAACCTCTGCCCCCGGGTTCAAG CAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGATGCCTGCCACCACACCCG GCTAATTTTTGTGCTTTTAGTGAAGACGGGTTTCACCATGTTGGCCAGGCTGGCCTCGAA CTCCTGACCTCATGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAG CCACTGCGCCTGGCCAAACTTTTTATTTTTAGATAATTATAGATTCCCATGCAACTTTAA GAACTAATACAAAGGGATCCCATGTACCCATGAGCCAGTTTTCCCCAATGGCAACATCTT ACAAAACTGTAGAATAATTTCATAGTCTGGATATTGACCTTGATACAGTCAAGACACAGA ATATTTCTGTCCCTACAAGGATCCCTCATGTCATCCTCTTATAGCCATGCCTACTCACAT TTGCCTTCACAGGCTCCTTAACCTCTAGCAACCACACATACATTCACCATTTTATAATTT TGTCAGTTCAAGAGTATACTATATGGAATCACATGGTATATAACTTTTGGGGATTGGCTT TTTTCCACTCAGCATAATTCTCTGGATATTCATCCAGGTTGTTTGTTGCATGTATCAATA GTTAATTCCTTTTTATTTCTGAGTAGGATACCATGGTATTGCCGTACCACAGCATGTTTA TTTATTATTTATTTATTGAGACAGGGTCTTGCCCTGTCACCGGGGATGAGTGCAGTGGCA GGATCATTGCTCATTGCAGCCTCAACCTCCTGGCTCAAGCAATCCTCCCAGCTTATCCTC CCAAGTAGCTGGGACAACAGGTGCACACCAACACACCTGGCTAATTCTTTTTTATTTTTA GTAGAGACAAGGTCTCGCTATGTTGCCCAGGCTGGTCTCAAACTCCTGGTCTCAAGCCAT CTTTCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCTGGCCCCCC ACAGTATGTTTAACCATTCACCTGTTGAAGAACAGCTGGGTTATCTTCAGTTTTTGGCTA TTAAAAGCTGCCATGGGAAGGGAGCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAG GCCGAGGCGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGA AACTCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGCACATCTGTAATC CCAGCTGCTCGAGTGGCTGAGCAAGAGAATCGCTTGAATGCGGCAGGTGGAGGTTGCAGC GAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCGTCTCAATA AATAAATAAATAAAAGCTGCCATGAACATTCATGAACAGGTTTTCGTGTGTCCATAAGTT TTCATTTTTCTGGGATCGATACACAGCAGTACAAATGGTGGGTCATAGGGTAGTGGTATG TTTCATTTTCTGAGAAACTGCTGGCTGGGTGTGGTGGCTCACGCCTGTAACCCCATCATT TTGGGAGGCTGAGGGGGGTCGAATGCTTGAGCCCAGGAGTTCAAGACCAGCCTGCGCAAC ATGGGGAGACTGTCTCTACAAAAAATATAGAAAATTAGATAGATGCGGTGGCATGCACCT GTGGTCCCACGACTTGGGAGGCTGAGGCAGAAGGGAAGATCCCTTGAATCTGGGAGGTTG AGGCTGCAGTGAGCTGTGATTTTGCCACTGCACTCCAGCCTGGGCTACAGAGTGAGATCC TGTCTCAAAAAAAAAAAACAAAAAACCAAAACAAACAAAAAACAAACCCGAAACAAACAA ACAAAAACCCAGAAACAAACCTGCTAAACCTTTCCAGAGCAGCTGTACTATTTTAAATTT ACACTGATGTAAACGTATGAGTGATCTAGTTTTTCTGCAGCTTTGCCAGCATTTGTTGTG ACTATTTTTTATTTTAGCCATTCTGATAGATGTATAGTACAGATGTATGGTACAAATTAA AACCGTCTCATTGTGGTTTTAATTTGCATTTCTCTGATGGCTAATGCTATTGAACGTTTT TTTCATGTATTTATTTGCTATCTGTATATCCTTTTCAGTCAACTATCTATATTTCTTACG CATTTTGAAATTGGATTGTTCTTTTGACTGTTGAATTTTAGTTCTTTATAGCTTCTAAAT ACTAGTCCTTTGTTAGACATGTGGCTTGTAAATATCTTTTCCCAGTCTACAGCTTGTCGT TTCATTACCTTAATAGGTCTTTTGCAGAGCAAGTTTTACATTTTGATGAAGTACAATTTA TCAACATTTTCTTTTACGGATCATGCTTTTGGTGTCAAGTCTAATAACTCTTAAAGAGTT CTGGGCATGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATC ACGAGGTCAGGAGTTCAAGACCTGCCTGGTCGAGATGGTGAAACCCCGTCTCTACTAAAA ATACAAAAAAAAAAAAAAAAAAAAAAATTAGCTGCGGGTAGTGGCAGGTGCCTGTAATCC CAGCTCCTCAGGAAGCTGAGGCAGGAGAATCGCTTGAACTCGGAGGGCAGAGGTTGCAGT GAGCCGAGATCATGCCATTGCACTCCAGCCTGGGAGACAGTGAGACTCCATCTCAGGGAA AAAAAAAAAAATCTTGAAGAGTTCTTAGAAGATCGTAAAGATTTTCTCTTATTTTTTTCT TTTAAGTTTTATAGCTTTATGTTTTATAAGTCTGTGACTCATTTTGAGTTAATTTTTATA TAAAGTGTAAGACTTAGGTCAAGGTTTTGTGTTTTTTTTCCCTAATGGATATTCACTTGC TGTAGCATCTTTTGCTGAAAAGGCCATCTTTCCTCCATTGAACTGCTTGCGTGCCTTTGT CAAAAATCAGTGGGGCATATTTGTGTGGGTCTATTTCTGGGTTCTCTATTCTTTCCATTG ATGTATATGTCTATCTCTCTGCAATACCACACAGACTTGACTACTGTAGCTAAGTCTTCA AATCAGGTAGACTGATTCCTCCCACTTTGTTCTTTTTTTATTCCTTCAAAATTGTTTTAG TCTAATTTCTTTAACTTTCCATATAAATTTTACAAGAATCTTGTTTATATCTACAATAAA ATCTTGCTGGGCCTTTGATCGAAATTGCGTTAAGCCTGCATACCAATCTGGGGACAACTG ACTTCTTTACTATATTGTCCTCCAGTCCTTGAACATGGTACATTTCTCTGTTTATTTAGA TCTTCTTTGATTTATTTCTTCAGCATTTTGTAGTTTCCAGCCAACAAGTCCTGTACATAT TTTTAAAAACTGACACCTAAGGATCTGGTGCAGAGTGGCTCACGCCTATAATCTTAGCAT TTTTGGAGATAGAGACGGCAGTATTGCTTGAGGCCAGGAGTTTGAGACCCACCTGGGCAA CATGGCCAGACCCCATCTCTTAAAAAAAAAAAAAAAAAAGACACCTCTGCACTAGGATCT GTACTAGGCATCTATGGACATCCTGCTGCCTGGAGGGTAGAAGAGCCCCCTGGCTGCTCC CTACACACTGCCTCCACTGCATTGCCTGTGTGTCTGGCAGCAGGTGGGGTGGGCTCTGGT GGCCTTTTGAAGATGAGCAGTGGTGCAAGTCCTGACTTCCCTCCCCCTGGCCTGCTCTGA CACCACCCAGCTGGGAGCGGGGGTGGCAGTTCAGACTCCTTCACTCAGTCTTTGCTGGCC TGGCTGGTTTTCGGCTGGAGTAGAGCAGTTACTGTCTGAAAGCTTTCCATCTTGCTAGGC AACCCCTTTTCTGGTCCTCTGGCTAGAGAGAACTGGCTTCTGTTAGTGCGTGTATTGTCT GTACCCATTGGCACTGCGTGCTTGCTGACTTCTTCAGCTCCAAGTCTGGGCCAGGGTACG TAGCACTGTGTTACTTCTTGGGTCTCTAGGTCCCTTGTTGGTCTTCCTTCTCTCTGCCTT CCAGAGTCTTCTTATGTCTTTTATATAATGTCCAGATATATATATAATTTTTTATATAAT GTCCAGATAATATTTTTATGTAACGTCCAGAGCTTTTAGTTGTACTTATTGGGAAGAATT GGGACAAGTACATCTACTCCATCTTCCTGAAAGTAAATGCTCTAAGTATTTTTCTAAATG GTGATTTTTTTCCCCCTAAGAACATTAAAGTGGGTGAAAAAATATTGAAAATTGAGAAGT AGGTATGTTAAAACTCACAGCACTATTTTAGGCTTAAATATTTCATATACCAAAAACATG ATTTATTATAATTTTATTTTCCTGGCTTTAATGGAAGCAAACTCATCAAAACATATTTTT CCAAGTCTACTTCTAGAGAAAGAATAACCGCTAAAAAGACACCAGCAGGGCACAGTGGCT CACACCTGTAATCCCAGCAATTTGGGAGGCTGAGGCAGGAAGATCATTTGAGCTCAGGAG TTTGAGCCCAGCCTGGGCAATAGAGTGAGATTTTGTCTTTAGTAAAAATAAATGAAAATT AGCCAGGTATGAGGGTGTGCAACTCTAGCCCCAGCTACTCAGAGGCTGAGGCAGGGAGAT TGCTTGAGCCCGTGAGGTCGAGGCTGCAGTGAGCTACGATCATGCCACTTCACTCCAGCC TGGACAAAAGAGCAAGACCCTGTCTCAAAAAAAGAAATTTAAAAAATACAATAAATAAAA ATGAAAAAATACACCAAAAAATACATGGGGCACACATGATTACTTATGCATGAGCCTTCT ATATGGTGGGGCACAGCTCTGTTGGATCCTGTCTTTATTTAAAGTTTCATTCATTGTGGA TATTTTTTGCATTAATTTTGATTTTTAAAAAATATTGCATTGAAATATTACTTATTTTGG CTGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATC GCCTGAGGTCAGGAGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCTCTCTCTATTAA AAATACAAAAATTAGCCAGGCATGGTGTTGGTCACCTGTAATCCCAGCTACTCAGGAGAC TGAGGCAGGAGAAATCACTCGAACTCAGGAGGCGGAAGTTGCAGTGAGCCGAGATCGTAC CACTGCACTCCAGCCTGGGCGACAGAGTGGGACTGTTTCAAAAAAAAAAAATTGCATTGA AATATTACTTATTTTGATGATTGAGATTTTTGGCCTCCCCTTAAGTTTTGCATGCAAGGT AAGGGCCTCATGGGCCTGGCTGCAGTCCCAGGCTGAGCTAGGCACTCCACAATATTTTGT TTGGGTAAAGTGATGGGTGGGCTCTAGAGCTCCCTCACAGCTGTATCCTTACCTCAAAGG GGCAGATTAACTTAGATTTACAGAAACGACAGCTGAGGAGGTAAATCTGAGTCCCTCTGG AGGTGAAGGTGCTTCTGAGATGGGACCTTCTATAAATAGGTTATAAGAACTTGCAGAAAC GAGGGCCCCGTTGGGCACAGGCCGTCCTGCACATACTGAACATTCCACTGGGGTGGGGCC TCTGCTCTCCCACTCCCAGTGCACCTCTGAAAACGAAGGTCCCAGAACCCGCATGCCACC GGGACAGGAAACGGAGCGGCTTCCAGGGCTCATGGGAACTGGTCTAATATTAGCAGTGTT TTTCTCATCTGGCCCTTGGGACGTCTCTATGGGGTAGGTGTTGTTATCACTCATTTCACA GATGAAGCAGCTTGGGCTGCCCCTGGGGAAGAGTGGATGCCTAGCTGTCATCCCAGATCT CTGCGTGTCATCCCGCCCTACCCCATCCTGCCTCACCCTTCATTCTGTGTCCTCTCCTGT GCCAGCTCTGGGCACATACCCAGGAATGCCTGGAACACCTTTCTGCTGCCTAGGCTGTAG GCTCAGACACCCCGAGAACAGCTTGATGTCACTCTATTGCCCATCCCTGGTCAAACACAA TGTCCTTCCTCCACCTTCCCACCAGCCTGCCTCCTGCCCCTGGCTATATTTAGGACTTTC TACAGTCTTTGCCACCAACCCCTTCTTAGGGTTTGAAGAGGGGCCACATCAGATATCTTT GGAAACCCATGGCAGGAGTGAGCTTTTCTCTGGGCACCTCTTATTTCCATCCTGTATCCT GGGTCTTTCCCACCTACTCAGGCTTTGGGTAAAAAGGCCAGGCTATTAGAACATCATGGG GGTGGCGAGGCCTGCAGGAGGGTGGCTTACCACCCATTCCGAGAAAAAAAATCCATGCTT GATAAAGCCTCCGGGACTCTAGTGGTAAAGTTATTAGTCAATCTTTCATCAGTGGTTCCT GGCCTTTTTATCCCAAACAACCTTTTATTTTTATCCTCCTAAGGTTTTAGCTTCTCTCCA AATAAAACTTTCTTAAGGACTACTTTTGTAGTTTTTAGGTAGTGAAAGATTCATCTAATA TTTCTGATCAGCATGAAATAACCAGTTGCTATACCAAAAGCAAGGAAATTTGATGCTTCA TTTATTCTGTAATATTCCATACACGATTTTAAATTATAATAGGCCAGGCGCCGTGGCTCA TGCCTGTAATCCCAGGACTTTGGGAGGCCAAGGTGGGCAGATCACTTGAGCTCAGGAGTT TGTGACTAGCCTGAGCAACATAGCAAGACCTCGTCTCTACAAAAAATGCAAAAATTAGCC AGGCATGCTGTCATGCACCTGAAGTCCAAGGTGCTGTGGAGGCTGAGGTGGGAGAATCGA TTGAGCCCAGGAGGTCTAGGCTACAGTGAGCCATGATCATACCACTGCACTCTAGCCTGA GTGGCACAGTGAGACCCTGTCTCAAAAACATAAACATAAAATAAAAATAAATAAATTATT ACGGGTGCAGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCGAGGCGGGCAGATC ACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAGCCCTGTCTCTACTAA AAATACAAAAATAAAATAAAATAAAACGAGCTTGGTGTGGTGGCAGGTGCCTGTAATCTC AGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGATTGCAATG AGCTGAGATCAGGACACTGCACTCCAGCCTGGGTGACAGAGCAAGACTGTCTCAAAAAAA TAAATAAATAAAAATAAATGAATAAATTATAACAATAGCTTTAGGTCCCCCATTATCAGG GAAAAGCCTTTAGAGATCATGTTGTCCAGCCCCTTCCTTTTTTAGACAGGAGAACTTACT CAGAGATAATAAGTAAATGACATACAGTTTATACAACAAAACTTCCTTGGGAAATGATGC TTTGCTTTTCCTGGGAGACCATTTAGTGTTAGGGTCAGGAGGAGCTATGGGGAGGTGAGG GCAGCCAGATGCAAGGGGAGTAGAGGTCTGGGCTGTGCCTGAGACTCTCACAGATCCTTC CCCTTCCTGACTTCCCAGGTCTGGTGTGACCTGCGTCAGGTTTCAGGGAGCTGGGCTGCA GACTGCTGATGCTCTAGTGCCTAGACCTGCAGCCTTGCTGTCTTCTCCCACCCCAGCTTG AGGACCAAATACCACTCTCCTCTCTGTTGGAGTGGATTTTTCTCCTAAAACCAAAGGAGG CACTCTTCTTCCCCAATCTGAAGTTTTTGTATTTTGCTATTACAGACCTGCTCTCTGGTC TCTAAATCTGGATTCCCAATGTACCCTGGGTGCCATAGAGTTGGCAGTTACTTTCCTGGG GGAAGAGGGTAGGACTTCAATGTTCTGAAAGTGACAGATCTCCGAGTTCCAGATATGGGT GTTCAGCAAATTTCTCAGTCTCTTCTAACAGGCCCTGCTTTGCAGGTGACCCGGCGCTTT GGGATCCCAGGGCTGAAGAAAATCATGGACTGGTTTGGCTACTATGGAGGCCCCTGCCGC GCCCCCTTGCAGGAGCTGAGCCCCGCTGAGGAGGAGGCACTGCGCATGGATTTCACCAGC AACGGCTGGCTCTGAGGGCAGGCAGGGTCCATGGCTGGCCTGAGCCCATCTCAGCCTCCT GCCTTGCACTTGCAGCCTGAAGCGGAGAGCACAGGGGGATGAGGGTGGCAGGCAGCGGGG AGCCGATAGAGGCTCCTTTGCCTGCTGTGGTCCTCCAGGCAGCCTTTCACAGGCACGCCC ATGCATATCTCCTATTCTAACGGCCCCTGACCTCTCCCTTTTGGATCCTAAACTGTGTCT CTGGTCTGAAGACTGGGAAGGAGCAATTTCTCAATTTATCTTTCTACTGTGGATGCTTTC CTACGCCCTGAGGCACATGAAGTCAGAAAGGAAGGGCAGAGGGGCAAGTAGGCACAGTAA GGGAATTTTCTTTTCTTTTTTTTTTTTTTTGAGACAGAGTTTCACTCTGTCACCCAGGCT GGAGTGCAATGGCATGATCTCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCC GAGTAGCTGGGATTACAGGCGCCTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGCAG AGATGGGGTTTCACCGTGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCAA CTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGCTGTGAGCCACTGCACCCGGCCGGGAA TTTATCAAAGGGGGGACTACTTAGATTTGGGGCTTCAAACCTGAGTCTAGCACAATGCAG CTGGAGGCCAGGGCTACTCCTACAAACCCAAGTTCTGACTCCTTCCAGGGAAGTATCAGC TTAAGAAACTTGATCAGGAAAGTGACACTGGTCTTTCAAAGAGCCCTCTTTACCCTCCCA TCCCTGCCCTCCACACTGCAAGCTGCATTCCAGCCACAACGCCCTTTTCTAAATCTATTT TCATTCATCTCCTATTCTGGTCTGTAGCCTTGATTCCAACCATTGAATGCACGGAGACAG CCCAGTGGCTTGTCAGATTGGTAAATAATGACACCTGGTGGATAAATGTTACATTCTAGA AGACTATTCTGGTCAGCCTAGGTCTGAAACACTAAGGAGACTTGGCCTGAGATAGGGCCA TCCACTTGCCTACAGGCACTCTGCTTTTATTATTAAAAATAGTCACTTTGTTACTATAAT AAAATTTAACAGAAAAAA OMIM ID 613597