Entrez gene ID | | 11282 |
Official gene symbol | | MGAT4B |
Full name | | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
Aliases | | ,GNT-IV,GNT-IVB, |
Gene summary | | This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q35 |
Gene position | | 179233952 - 179224597 Map Viewer |
Gene orientation | | minus |
Gene size | | 9356 bp |
Gene sequence |
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OMIM ID | | 604561 |
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