Entrez gene ID | | 11315 |
Official gene symbol | | PARK7 |
Full name | | Parkinson disease (autosomal recessive, early onset) 7 |
Aliases | | ,DJ-1,DJ1,FLJ27376,FLJ34360,FLJ92274, |
Gene summary | | The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p36.23 |
Gene position | | 8021714 - 8045342 Map Viewer |
Gene orientation | | plus |
Gene size | | 23629 bp |
Gene sequence |
| |
OMIM ID | | 602533 |