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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TXNRD3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID114112
Official gene symbolTXNRD3
Full namethioredoxin reductase 3
Aliases,TGR,TR2,TRXR3,
Gene summaryThis gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q21.3
Gene position126373967 - 126325895  Map Viewer
Gene orientationminus
Gene size48073 bp
Gene sequence
OMIM ID606235