Entrez gene ID | | 114112 |
Official gene symbol | | TXNRD3 |
Full name | | thioredoxin reductase 3 |
Aliases | | ,TGR,TR2,TRXR3, |
Gene summary | | This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q21.3 |
Gene position | | 126373967 - 126325895 Map Viewer |
Gene orientation | | minus |
Gene size | | 48073 bp |
Gene sequence |
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OMIM ID | | 606235 |
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