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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for THEM4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID117145
Official gene symbolTHEM4
Full namethioesterase superfamily member 4
Aliases,CTMP,MGC29636,
Gene summaryProtein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21
Gene position151882113 - 151846060  Map Viewer
Gene orientationminus
Gene size36054 bp
Gene sequence
OMIM ID606388