Entrez gene ID | | 117145 |
Official gene symbol | | THEM4 |
Full name | | thioesterase superfamily member 4 |
Aliases | | ,CTMP,MGC29636, |
Gene summary | | Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q21 |
Gene position | | 151882113 - 151846060 Map Viewer |
Gene orientation | | minus |
Gene size | | 36054 bp |
Gene sequence |
| |
OMIM ID | | 606388 |
|