Entrez gene ID | | 120892 |
Official gene symbol | | LRRK2 |
Full name | | leucine-rich repeat kinase 2 |
Aliases | | ,AURA17,DARDARIN,PARK8,RIPK7,ROCO2, |
Gene summary | | This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q12 |
Gene position | | 40618813 - 40763087 Map Viewer |
Gene orientation | | plus |
Gene size | | 144275 bp |
Gene sequence |
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OMIM ID | | 609007 |
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