Entrez gene ID | | 133 |
Official gene symbol | | ADM |
Full name | | adrenomedullin |
Aliases | | ,AM, |
Gene summary | | Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.4 |
Gene position | | 10326642 - 10328923 Map Viewer |
Gene orientation | | plus |
Gene size | | 2282 bp |
Gene sequence |
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OMIM ID | | 103275 |
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