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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for COX6A1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1337 Official gene symbol COX6A1 Full name cytochrome c oxidase subunit VIa polypeptide 1 Aliases ,COX6A,COX6AL,MGC104500, Gene summary Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq] Location Chromosome: 12   Locus: 12q24.2|12q24.2 Gene position 120875904 - 120878532  Map Viewer Gene orientation plus Gene size 2629 bp Gene sequence >COX6A1:11452434..11455062:Length=2629 CGGCGCTGCGGCAGTCCAGATCAAAAATGGCGGTAGTTGGTGTGTCCTCGGTTTCTCGGC TGCTGGGTCGGTCCCGCCCACAGCTGGGGCGGCCTATGTCGAGTGGCGCCCATGGCGAAG AGGGCTCAGGTACTGGGGCCGGGGTCGACGGGTCGAGCCTCAGCCCCACTCGGGCGAGAC AGGGAGGGACTGTGACCTTGGCCCGAGGCCTTGCGGGAGGGAAAGTGAGACCCGGGCCCG CCCCATACCGGCGCTGAACGTTTGTGGCTTCTCCGCAGCTCGCATGTGGAAGACTCTCAC CTTCTTCGTCGCGCTCCCCGGGGTGGCAGTCAGCATGCTGAATGTGTACCTGAAGTCGCA CCACGGAGAGCACGAGAGACCCGAGTTCATCGCCTACCCCCATCTCCGCATCAGGACCAA GGTACGCCCTTGTACATCTCTTCAAGCGTCCGTTCTCTTTTCGTTATGTGTGCCTTAGTG CAAGTTCTTCATTCTCTGAAGGCATGGGTGCCAGGCGTGTACAGCTTGTTTATCCTCACA AACAGAAAATGTATTTTCTTCCATTTTGTGGATGGACAGCTGACACTTGGGATTACGTCT CAATTCTCTTCTTCAAGGTCATACAATAAGTGCTCTTCAGTTTCCCTTTTCTCCGATTCA TCCTACCTCCTGCCTTCTGAGACAGTTCTTTTTTTTTTTTTTTTTTTTTTTTTTACTTCT GAGACAGTTCTGAAACAGGTGTCCGTTGTGTAAAGCCTGGAGGTTTGGGAAATCCAATTA GAGTGGCAAAGTCTGAAGGTGGTTCGCGTAAGCGAACCCAGCAGCTACATGGGAGGCTGA AGCAGGAGAATCCCTTGAACCTAGGAGGCGGAGTTTGCAGGGAGCTGAGATCGTGCCACT GCACTCCGGCCTGGGCAACAGAGCGAGACTCTGGTCTCAAAACAAAACAAAACAGCAACA ACAAAACATGGGCATCTGGCAGCTACTAGTTGCATAATGAAGAGACTGACAGCTTTCTCT ATTCCCCACCAATACCTTTTCTCGACTGTTTTATCATTGGTTGTTGATGTAGATATATTA CAATGTTGTGTCCTCTGTTGTTTGCTGTATCTTTAACAAGGGCTTATTCTGATTCTTCAA TACTGGCCATGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGG TGGATCGCCGGAGGTCAGGAGTTCAAGACCAGCCTCGTCAACATGGCGAAACACTATCTC TACTAAAAGTACAAAAAGTAGCCGGGCGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCG GGAGGCTGCGGTGGGAGAATCTAGGAGGTTGAACCCAGGAGGAGGAGGTTGCAGTGAGCC AAGATCCAGCCATTGCACTGCAGCCTGGGCAACAGGAGTGAAACTCCGTCTCAAAAAAAA ATAGTAATAATATACTTGATCTTAGCCAAAAGGCCGAGAAGTGATGAAAAAAGTTATTAT TATTATTATTATTATTACATCACCTAGCCCATATAGGACTGGCCTTGTAGAAACTTAACC TAGACTCTTGAATTTGTTGAGTCTTTGAGCGGCACTCCCATCCTTGTACAATGCAATTAG AAGCCAAACAGTAAAGGTTTCTCAGCCTCAGCACTGTTGACATTTGGGGCTGGGTAATTC TTGTTGGGGGGCTATCTTGTGCATTGTGAAATGTTTAGCCATATCCTTGGCCTGTACCCA CTAGGTGGCAGTAGTACCTGCGCAACCCCACTCCCGCTTCCCCCTCCCCCGCCCCCATCA CAGTGTCTCCCGATACTACCCAGTGTGCCCTGAAGGGGCAAAATCACCCTGGGTTGGAGA CCGTTGCCCTAAAGTAATGCTTTTCAAAGGTAATAGGCAAGATAATTCAGGGTGGGCTGC AGTTTCCCAGCCCAGATATTGTTTGAAGTCTGGGATGGTGCCAGAAATCTGCATTTAATT AAGCATCTCCCTCCCCTAATACTGCCACCATTTTGATATAGGTGATTTGAGGATTACACT TTCATAAACACAGCACTGGATATACTAGTTACTAGGGAGAGGATGATGAGTAACTAACTT GAGCTTGCATTTTCTGCCATCCATATTTGTTTCTGGAATTAAAACTGTCCTGTAGCCAGG ATAACTTTAAGGGCTCCCCTGGTAGTTATAAGAGCTCCTTAAATAATGGGAAGGTTGAAC TACACCAGTAGATAAAGGACTAATTTCCATTTTGTTTTTATATATGATCTGTCACCCCGT TATAAGCAGTTCATGACGGTGTTCTTTCTAAATTATTTTCTGGAATTATCTAACTGACAT CTTCACTCCACAGCCGTTTCCCTGGGGAGATGGTAACCATACTCTATTCCATAACCCTCA TGTGAATCCACTTCCAACTGGCTACGAAGATGAATAAAGAGAATCTGGACCACTACCCGG GCACCAGGGACCACAGCACTGGTTTGGACCGTTACTCTGCACATGGACCAGAAAAAGTAT ATGGGACCTTAAGCTCACCTTCTTTACTTGTATCAAATGATGACTGGTATACTGGTCTCC CATCCCTTTGCTTGTGGCAGGAGATGGCTTAAATAAATAACTTAAATTT OMIM ID 602072