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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RAET1E (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID135250
Official gene symbolRAET1E
Full nameretinoic acid early transcript 1E
Aliases,LETAL,MGC125308,MGC125309,RAET1E2,ULBP4,bA350J20.7,
Gene summaryMembers of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1; MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand for NKG2D (KLRK1; MIM 611817), which is expressed on the surface of several types of immune cells and is involved in innate and adaptive immune responses (summary by Radosavljevic et al. (2002) [PubMed 11827464] and Cao et al. (2007) [PubMed 17470428]).[supplied by OMIM]
LocationChromosome: 6   Locus: 6q25.1
Gene position150212097 - 150209601  Map Viewer
Gene orientationminus
Gene size2497 bp
Gene sequence
OMIM ID609243