Entrez gene ID | | 1363 |
Official gene symbol | | CPE |
Full name | | carboxypeptidase E |
Aliases | | ,-, |
Gene summary | | This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q32.3 |
Gene position | | 166300097 - 166419482 Map Viewer |
Gene orientation | | plus |
Gene size | | 119386 bp |
Gene sequence |
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