Entrez gene ID | | 1393 |
Official gene symbol | | CRHBP |
Full name | | corticotropin releasing hormone binding protein |
Aliases | | ,CRF-BP,CRFBP, |
Gene summary | | Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q11.2-q13.3 |
Gene position | | 76248680 - 76265299 Map Viewer |
Gene orientation | | plus |
Gene size | | 16620 bp |
Gene sequence |
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OMIM ID | | 122559 |