Entrez gene ID | | 1399 |
Official gene symbol | | CRKL |
Full name | | v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
Aliases | | ,-, |
Gene summary | | This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
Location | | Chromosome: 22 Locus: 22q11|22q11.21 |
Gene position | | 21271714 - 21308037 Map Viewer |
Gene orientation | | plus |
Gene size | | 36324 bp |
Gene sequence |
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