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Gene information for CRYZ (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1429
Official gene symbolCRYZ
Full namecrystallin, zeta (quinone reductase)
Aliases,DKFZp779E0834,FLJ41475,
Gene summaryCrystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p31-p22
Gene position75199092 - 75171170  Map Viewer
Gene orientationminus
Gene size27923 bp
Gene sequence
OMIM ID123691