Entrez gene ID | | 154 |
Official gene symbol | | ADRB2 |
Full name | | adrenergic, beta-2-, receptor, surface |
Aliases | | ,ADRB2R,ADRBR,B2AR,BAR,BETA2AR, |
Gene summary | | This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q31-q32 |
Gene position | | 148206156 - 148208197 Map Viewer |
Gene orientation | | plus |
Gene size | | 2042 bp |
Gene sequence |
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OMIM ID | | 109690 |
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