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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP1A1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1543 Official gene symbol CYP1A1 Full name cytochrome P450, family 1, subfamily A, polypeptide 1 Aliases ,AHH,AHRR,CP11,CYP1,P1-450,P450-C,P450DX, Gene summary This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq] Location Chromosome: 15   Locus: 15q24.1 Gene position 75017877 - 75011883  Map Viewer Gene orientation minus Gene size 5995 bp Gene sequence >CYP1A1:complement(45802440..45808434):Length=5995 CTCACCCTGAAGGTGACAGTTCCTTGGAACCTTCCCTGATCCTTGTGATCCCAGGCTCCA AGAGTCCACCCTTCCCAGCTCAGCTCAGTACCTCAGGTGAGTTGCTGGGGGACTTCTGGC TTGCCCTTTCTCTCCCAATAAAAGGAACATTTTGGTGCCTCCAGGACTTCTTAGGTAGCT ACCTGTCTAGCACCTCCAAAAAGGGAGGCTCAGAGTGTTTTTAGTGACCAGGCAGTCTAG CCCCCTAGTGGGGAAACTGAGGCCAGGGGAAGAGGAGGACTTGCCCATGGTCCCACAGCT GGTACCAGACCTCTAGATACAGATGGCATCTCATTCAGGACTTCAGGACCCAGGCTCCAG CTCCATCCCCTAGTGAGTGTCTCCCTGCCTACCCTGGGGCTTCCCCATCAAGGCCACCTG GCAGGCTGGAATATGTGCAGCCCCTCCCTCAGGCTTTCTGATGACAGGGGCTTCTCCTTG GGTGGACAGGGTGGATGGAGGGGGTGGGCTGGGTTCTTACCAGCTGTACCCTGCCCTAGC CTAAGAAGCTACCCCTGGCAGATTTTACCCTCCTAAGGGTGGCTTGTCAGTGCTGAGATG TCCTAGACAGCTGGGACAATAGAGGCAGATCTGTGCAGGAGTCCCAGGCCTTTCCTATCT CATTGACCATCTTCTTTGTCCTTTGCTGGGAGACAATCAGGGTGACAGATTGCCAACTGC AGGGAGCTGGAAATACCAGTCCCTAAAAACTCACCAGTCACATCTCCCTTGGCCTCCTAC CATCTTACAAAGGCTGCAGGTCCTTGGGATACCCACTGTGCAGAAGGGGACACCATAGCA CACCAAAGCCTGGCACTGTCCCCTGTTGACTCAGGGATCTAGTGTGCTTTGATATTTAGC CCCTCCAGGAAGCCTCCCTCCACTATAATACTTGTGGTAGGAACCATCCATCTCCCTGTC TTGTGAGGTTCTCCTGTGGGGAGCCTAACTGGTAAGACTGTCAGGTTCCCCACAGCAGAT CTGGGTTTTCTCTTCCCTCTGGATCCAGCTGGGTACTCTGAACTGAGAGATCTTGTCTTA CCCTCTCTCAGATGTTGAAATTGGACCCCAGAAAAGTAAAATGTGCAGTCCAAGATCACT TTGACTAGAATGTTGGGTCTACTGACCTCTAGTCCAGGGTAACAGGCAGAGATGCCTGAT ATGTTGGAGAGAGTGGTTTATGAATTTAAACACCCTTTTTAGGTCAAGCTTACAGAGAAA GTATTGCCTCAGTTTCCTTTCAGTTTAGATCCATTCCTGATTTCCCTGATTCCAGTCTGG GGTTTTCTTACAGCCTAGTGGGAACCTTCCATTTATTCTCTGCTCTCTGGTAACCTGCAA AAGGGGGAGGTCCAAACTGTTCATTCATTGAGAATTGAGCCAAAAAAAAACCCTGGCCTG GATTTCTCTGACTAAAGAGCTCAATCTAGCTGGTCTCCAGCTGCCTTTAAACTGTGGATC AGTTGAACTCAGAGAGCTGGGGCTGAAAGCAATGTGGTTTGGGAAGTGGCCATCCTGTCC CCTATCTCTTCCTCAGTCTGTCCTGGGGTCTGGTGGGATTTCCTGCATCCTGGGATTGAG CAGCAGAGAACTGAGGGTTCTGGGAAAATTCCTTCATTGATCTGACCACTCTTCAAAAGG AGGTACATGTGACAGCAGCTGGAAATTTCCAGGGAAGTGTCCCTAAGGAGTCTGAGTCCT GGCTCTGTCACTGATTGCTGGGGGACTTTGGACAAGTCAGCGCTGCTTCCCCCAAATGTT AAATGAGGCTAAAGGATCAGATGATCCCTAATTCCCCTGAGAACATGATTTTCCTAAGTG TGGTGGGTAGGACTCGGGGTGATACACCTTGATTATGTGTTTATTTTAATGTGTTAGGGG AAAAATCAAACTTGTACTTTCACATAGATATTGTTTATGATGATATGTAGGTAGATTTAA AGTTGATTTTAGGAAAATGTGAAGTAAATAACAGTACTGGTACTATGTGGAAATCACAGA TTGACATTGGAAGATGTCAGTTTAGATTGGTACAGCAGTTAAGAGAAAGCGTTCTGGAAT TAGGCAACTTGGCTTGGGAGTCTGCATCCAACACTTTCTGGCTGTGTGACCTTGGGCAAG TTACTTACCTTCTCTGAGCCTCATTGCAGGCTACTTCATAGATTTGTGGCCAGGGCTGAA TGAAGAAGGACTGTGAAATTCTTAGCCCACAGTGGTAGTTCAACAACTTCTCCCCACCTC ACCCTCTTCTTCATGCCCAGTAAGCAGTTCTGGTGGAAAGGTTTCCCCTTTCCCTGACAC TCTAGATATTGGCTTTTCTCATCCCCCAATCTGACGGCTTGACTTTTTTTCTTCCTGCAC CTTCTCTCAGCAGCCACCTCCAAGATCCCTACACTGATCATGCTTTTCCCAATCTCCATG TCGGCCACGGAGTTTCTTCTGGCCTCTGTCATCTTCTGTCTGGTATTCTGGGTAATCAGG GCCTCAAGACCTCAGGTCCCCAAAGGCCTGAAGAATCCACCAGGGCCATGGGGCTGGCCT CTGATTGGGCACATGCTGACCCTGGGAAAGAACCCGCACCTGGCACTGTCAAGGATGAGC CAGCAGTATGGGGACGTGCTGCAGATCCGAATTGGCTCCACACCCGTGGTGGTGCTGAGC GGCCTGGACACCATCCGGCAGGCCCTGGTGCGGCAGGGCGATGATTTCAAGGGCCGGCCC GACCTCTACACCTTCACCCTCATCAGTAATGGTCAGAGCATGTCCTTCAGCCCAGACTCT GGACCAGTGTGGGCTGCCCGCCGGCGCCTGGCCCAGAATGGCCTGAAAAGTTTCTCCATT GCCTCTGACCCAGCCTCCTCAACCTCCTGCTACCTGGAAGAGCATGTGAGCAAGGAGGCT GAGGTCCTGATAAGCACGTTGCAGGAGCTGATGGCAGGGCCTGGGCACTTTAACCCCTAC AGGTATGTGGTGGTATCAGTGACCAATGTCATCTGTGCCATTTGCTTTGGCCGGCGCTAT GACCACAACCACCAAGAACTGCTTAGCCTAGTCAACCTGAATAATAATTTCGGGGAGGTG GTTGGCTCTGGAAACCCAGCTGACTTCATCCCTATTCTTCGCTACCTACCCAACCCTTCC CTGAATGCCTTCAAGGACCTGAATGAGAAGTTCTACAGCTTCATGCAGAAGATGGTCAAG GAGCACTACAAAACCTTTGAGAAGGTACAGTCTGGGGAAAGGCAGGTGGGTGGTGGGAAG CAGATGGCATCAGGGCCTGGGAGGTCAAAGGTAAGAGGAACTGCATGGGGCTTGGCAAGT TCTCAGGAAGGCTTCAACCTGGGATCTTGAAGCCAGTTGTGGAATAGTCTTCTTCCTTGG CAGGGAAATAGAACTTTATCTTGACTAACCCTTCCATGCTTCCACAGACAGCAATAGCCA CTGAAGAGTCATTACATGCAGGACCCTGGGGCAGTTGCTGAGGGAGCCAGGAAGAGTTAA AGAGTTCATCTCCTGGCCTCATAATAGAAAGAAGATAAAGAGCACATCCAGATGATAACA GTACAAGACGCTGTGTGTCAAATGTCCCATGAGTTGGGGCTAGCAGCATTCTAAGGTAGT AGGAGAGAGCCTTGCAGAGGCAGAGAGAAGCTGGGACAACAGCCTCAGGGGGCATCACCT CCAGAACAAATGTGCTAGGAATAGTGAAGGACCAGACCTGGATGGAGAGGTAGCTCTGGG TTTGAGATCTTGCTCACCTGTGGACTTTCCCTACCTAAGGGCCACATCCGGGACATCACA GACAGCCTGATTGAGCACTGTCAGGAGAAGCAGCTGGATGAGAACGCCAATGTCCAGCTG TCAGATGAGAAGATCATTAACATCGTCTTGGACCTCTTTGGAGCTGGTATGGTTACCCCA TTGTGTCCTTCCTGTGCTCAAGTGCCCTGACCTGCTGCTGCCTGCCTAACTTCTTCTGTT CTACCCTGTCCAGGGTTTGACACAGTCACAACTGCTATCTCCTGGAGCCTCATGTATTTG GTGATGAACCCCAGGGTACAGAGAAAGATCCAAGAGGAGCTAGGTAGGTAGTGGCTCCCT TCAAAGGGGTCAGTGCCAGGGGTCTGGCCAGGTCTAGGCAGCCCCTGCATCCATCTTGTC CCTGTGTTCTGCAGACACAGTGATTGGCAGGTCACGGCGGCCCCGGCTCTCTGACAGATC CCATCTGCCCTATATGGAGGCCTTCATCCTGGAGACCTTCCGACACTCTTCCTTCGTCCC CTTCACCATCCCCCACAGGTAAGGCCCCATGGAGCCACTGCTGTCTGTTACTGATCTTAC TCCGGACCACATACCTGATTAGGGTTAGTGGGAGGGACACGGCATGGGAGACAGGGAGAT TTGCCTGTTGCCCTGAGCCTGACTGAGCTTCCTTTCTCCCTAGCACAACAAGAGACACAA GTTTGAAAGGCTTTTACATCCCCAAGGGGCGTTGTGTCTTTGTAAACCAGTGGCAGATCA ACCATGACCAGTAAGTTCAGAGATGCAGAGGAAAGGCTGGGTCCACCCTCTTAAGCTCTT ATATATGATTAATACAATCATTGCATTGATCCTCCTGTCCATGGGCTGCTTGCCTGTCCT CTATCCTTTGGGGCTGGAGCTCCACTCACTTGACACTTCTGAGCCCTGAACTGCCACTTC AGCTGTCTCCCTCTGGTTACAGGAAGCTATGGGTCAACCCATCTGAGTTCCTACCTGAAC GGTTTCTCACCCCTGATGGTGCTATCGACAAGGTGTTAAGTGAGAAGGTGATTATCTTTG GCATGGGCAAGCGGAAGTGTATCGGTGAGACCATTGCCCGCTGGGAGGTCTTTCTCTTCC TGGCTATCCTGCTGCAACGGGTGGAATTCAGCGTGCCACTGGGCGTGAAGGTGGACATGA CCCCCATCTATGGGCTAACCATGAAGCATGCCTGCTGTGAGCACTTCCAAATGCAGCTGC GCTCTTAGGTGCTTGAGAGCCCTGAGGCCTAGACTCTGTCTACCTGGTCTGGTTGGGCAG CCAGACCAGCAGGCTGGCCTATGTGGTCTAAGGTTCAGCCTGAAACTCATAGACACTGAT CTGGCTGCAGTTTTGCTATCTGGGCTGTGGGCAAGCCTAAGGGATCCTGCCTGCCCCTAC CCTGGACTTGCCTCTGCACACCCTCCAGAGACAACAGGTAAAACAGGGCCACATAGATGC TGATGGAGCCTTCCCAAGTTGTGCTTGAGCCAGGAGGCCTGCTAGGGTTAGGAGGTCCTT AGGCCTCTGAGAAGCTCTGAAGAACTCTCTGGAAGCCCCTGGGCCCAGTACCTAGCTGGC TCTGTGAGGGTGCTGACTGGCTTCAGCAAGTTAGAACTAGCCAAACCAGGACCCTGTCCA ATCTTTGACAATTGGGAGCTGCCAAGAGTGAAGGGAAGAGACAGCCCAGGATACTGGCAC AGAGGTAGTCTCACTGCTTGAACTAGGCTGAGCAATCTGACCCTATGGGTCTAGGACACA GTTCCTGGGAACATCACATTCCTCTGCCCTTCCTGCAGGCAGGAACAAACAGGGCTGCCT TCTGGCCTTGTAAGACCCTTATTGCTGTCCTGGAGGGGCTGGGGACTTGTGTCTGCGGGG ATCAGAGCGCACAGGGAGTGCACATATCCAGGCACCAGGACTAGGGCTGGAGTGAGGGGG GGGTATTTCAATTACCTTCTATTGGTCTCCCTTCTCTACACTCTTGTAATAAAATGTCTA TTTTTAATGTTTGTACACAACAATCCTTCTATTCTAGCCTGCATTGAGCTTGCATGCTTG CATAAGAGCTTAAGAACCATTGATTTAATGTAATAGGGAAAATTCTAACCCAGGTATCCA AAAATGTGTAAGAACAACTACCTGAGCTAAATAAAGATATTGTTCAGAAATCCTA OMIM ID 108330