Home

Search

Browse

RAGs

User guide

FAQs

Links

Questions

Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP1B1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1545 Official gene symbol CYP1B1 Full name cytochrome P450, family 1, subfamily B, polypeptide 1 Aliases ,CP1B,GLC3A,P4501B1, Gene summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq] Location Chromosome: 2   Locus: 2p21 Gene position 38303323 - 38294746  Map Viewer Gene orientation minus Gene size 8578 bp Gene sequence >CYP1B1:complement(17116633..17125210):Length=8578 AAAACCCGGAGGAGCGGGATGGCGCGCTTTGACTCTGGAGTGGGAGTGGGAGCGAGCGCT TCTGCGACTCCAGTTGTGAGAGCCGCAAGGGCATGGGAATTGACGCCACTCACCGACCCC CAGTCTCAATCTCAACGCTGTGAGGAAACCTCGACTTTGCCAGGTCCCCAAGGGCAGCGG GGCTCGGCGAGCGAGGCACCCTTCTCCGTCCCCATCCCAATCCAAGCGCTCCTGGCACTG ACGACGCCAAGAGACTCGAGTGGGAGTTAAAGCTTCCAGTGAGGGCAGCAGGTGTCCAGG CCGGGCTGCGGGTTCCTGTTGACGTCTTGCCCTAGGCAAAGGTCCCAGTTCCTTCTCGGA GCCGGCTGTCCCGCGCCACTGGAAACCGCACCTCCCCGCAGGTCAGTCTGTCTGCCGAGG CGCTGCCCGGCGACCTCTTCAGATGGATTATTACAGGTAGCGGGTGGCGTGGTAGGTACT TTAAAGGAAATCAAGCGCCACCGCCTCGATGCCCGCAGCGTTGTCCCCAGATTGCAGGAA CCGTTACGCGCCTTGCGGGGAGGGGAAGGGTTTGGCGCTGGGTTACAGCGAGGTGGAAAC ACGCCCCTTCTCTTCTCCAAGGGAGAGTGGGTTGGGGATGGGAAGGGGCGTCTTCGGCCA TTTCTCCAGAGAGTCAGCTCCGACCTCTCCACCCAACGGCACTCAGTCCCCAGAGGCTGG GGTAGGGGCGTGGGGCGCCCGCTCCTGTCTCTGCACCCCTGAGTGTCACGCCTTCTCCTC TCTGTCCCCAGCATGGGCACCAGCCTCAGCCCGAACGACCCTTGGCCGCTAAACCCGCTG TCCATCCAGCAGACCACGCTCCTGCTACTCCTGTCGGTGCTGGCCACTGTGCATGTGGGC CAGCGGCTGCTGAGGCAACGGAGGCGGCAGCTCCGGTCCGCGCCCCCGGGCCCGTTTGCG TGGCCACTGATCGGAAACGCGGCGGCGGTGGGCCAGGCGGCTCACCTCTCGTTCGCTCGC CTGGCGCGGCGCTACGGCGACGTTTTCCAGATCCGCCTGGGCAGCTGCCCCATAGTGGTG CTGAATGGCGAGCGCGCCATCCACCAGGCCCTGGTGCAGCAGGGCTCGGCCTTCGCCGAC CGGCCGGCCTTCGCCTCCTTCCGTGTGGTGTCCGGCGGCCGCAGCATGGCTTTCGGCCAC TACTCGGAGCACTGGAAGGTGCAGCGGCGCGCAGCCCACAGCATGATGCGCAACTTCTTC ACGCGCCAGCCGCGCAGCCGCCAAGTCCTCGAGGGCCACGTGCTGAGCGAGGCGCGCGAG CTGGTGGCGCTGCTGGTGCGCGGCAGCGCGGACGGCGCCTTCCTCGACCCGAGGCCGCTG ACCGTCGTGGCCGTGGCCAACGTCATGAGTGCCGTGTGTTTCGGCTGCCGCTACAGCCAC GACGACCCCGAGTTCCGTGAGCTGCTCAGCCACAACGAAGAGTTCGGGCGCACGGTGGGC GCGGGCAGCCTGGTGGACGTGATGCCCTGGCTGCAGTACTTCCCCAACCCGGTGCGCACC GTTTTCCGCGAATTCGAGCAGCTCAACCGCAACTTCAGCAACTTCATCCTGGACAAGTTC TTGAGGCACTGCGAAAGCCTTCGGCCCGGGGCCGCCCCCCGCGACATGATGGACGCCTTT ATCCTCTCTGCGGAAAAGAAGGCGGCCGGGGACTCGCACGGTGGTGGCGCGCGGCTGGAT TTGGAGAACGTACCGGCCACTATCACTGACATCTTCGGCGCCAGCCAGGACACCCTGTCC ACCGCGCTGCAGTGGCTGCTCCTCCTCTTCACCAGGTAAAGCCTCTGGGAGGCGTGGGCC AGGTCTTTTCTCCTCTGAAAAAGGCGGAGTAGAGACAGAATATGCTGAGTTTGCAAGCAG GGCCCCGGGTTTGGGGTTTCGCTCCAGGTCCCCACCCCTCAAAACCAAGATCGCGTCGGT AAAGGGACTCACAGTGAGGGCTGCGACACGCGCACGCGCCCCACCCAGCGGTGCCCCGAC CCCTCCGGTCTCCTATCTTGTCTCTATCGTCCCCTCCCCTGCTTGCGAGTGAGAACACAT TTGCAAAGACCCCTCCACCCCCCGGAAAAACAAGAGTTTTTAAATGCTTGGAGATGAGCC CTGATATCTCTCTCCCTGGCGCATTACAATCAGAACTGGAATAGTTCCGAAAGAAAAGGT AATGTCATAAATATGTTAAACACAGCAGCCTCTCCTAGGCTAGTCCTCGGCGTGCATCCG AGGCCGCCCAGCCCTGGCGCTAAAAGCGGGCCGCCCGTCAGGGCTTTGTTCCAGGCCAAG GAAGCCCATGGAGGCCGGGCCAGCCGACAGGTAACCCGCACAGAAACTTTCAGAAGGCGG CCACAACTAGCGGGCAGCGCTAGGTTTATAAAACCTCCGCGCTAGGAGTTTGAGAAATGC CGGGGTAGAAGACAAGAAGCAGTCACTTTTACGAAAGCAGAGTAGCATTCAGAAAGGCAG ATGGGATATCCAGGAGGCGCCTGCAGACGTTTCTGGCCCCTGCGCTTGGCTCAGTTAGCG GACCCCCTGATGCCCACGTTGGTCTCTACTAAGCACGGATTCAACAGGTCCCTGGTGTCG GGTTGCCAGATTTGGCAAAAGAAAAGTAAGTTTTACACGGGAATACTCACACTAAAAGAT TAGCCCTTGTTGATCTGAAATCCATATTTAACTGGGCGGCCTGTAGTATTTACTGTGGAA ACACTATCCCTAGGGGCAAATGTTTCGCAAGGCAAATTTTGATTGCCGAAGAGACCAGAA ATCCTGGTTTTGTGTCATTTCTTGGAGCACAAGTGAGCAGTTGGAGATGCTGAATCTGCA GGCGCCACAGAAAGGTGTTTGGAAGGCAGAGAATGACTCTTTCCTTATTAAAATCCACTG CAATCTATATTTCCTTAGATACTGTACAGCTACCTTCACAAATTAAAAGTTTCTGTATAC TTAAAATGGCTTTTTAGTATTAAAATCATAGAAACACCCATGGTGGGTGAGGGAGAGGCA GAAATCGAATAAAGAAAAGTCAACCAGAGATCAGGGAAAAGGAAATCCCGGAATAGGTTC CATAGGTTTTTGTGCATCCGCAGATAGGCATTTTAACTTTTGAAACGGCCTTTGTTTTTC ATTAGAACCACAATAGTTCTCCGAGTACTCCAATTAGGCGGCAAAAAGAAATAAAACAAT TTGGAGGTCACTTTCAATTCAATATGCTGATACTTTTTTTTTCCTTTTTAGTGAAAAGAC GTATGACAGGGCTTGGCAAATTACACGATCTGTTTTTGTATATACGTTTTATTGACGCAG TCATGCCCATTCATTTATACATTGTCGATGGCTGCGTTCACTCTACAACACAAGGCAGAG CAGAGTAGTGCAACAAAGAGGGTTTGGTCCACAAAGTCTAAAATAGATACTCTCTGGCTC TCCCCACCATACATGTTTCTATGAAAAAAGTTGGCAGACTCCTGCAATATAATGTTGAAG AAGCGATTCTAAAAATAACTCCACTTCATCACATACGTGTATACATTTTTTTTCGGAGTT GCAAACAATCAGTTACTTGTTTTTTGACTTCTAACACTTTGACTCAAGGTAGTGGACATT TCTAATCTTTTAATATTTATTTTGGTAATTTTTGATGGCTATATAGTATTTTGCTATGAT AATGTATAGTTATATATAATCATTTATTGAACTTTAATGTTGGTCATTGGCCTTGATTGC ATTTTTAAAATTTTTATTTTAATTTTATGTATTTACTTACCTTAGAGACAGGGTCTCACT ACCTTACCCAGGCTGGTCCCAAACTCCTGGGCTCAAGCAGTTCTCCCGCCGCTGTCTGGC AGGTAGCTGGGGCTACAGGCGTGTACCACCATGCCTGGCTAATTTTTAGAATTTTAGGTC CTGTTGTGGTTACATATTTTTGTATCTCTTAAATTATTTTCTGAAAATACATTTCTAGGC ATGGATTACTGGGTTTAAAATGAGGCGGGAAGAGGTTACCTTCATGTCTCTTGCCTCGTA TTAAGATTTTGTTTTTTAAAAAGATTGTATCAGTTTGTATCATCAACAGTGAATAAGTAC TACAGTTTGTACCATAATTTTATGAACATTGGGTATTTGCTTTCAAATTTAAAAAATACA GTATGTAGCTTTATCCATCAGGACACCAATTATCTTTGTATAAAATGAGAACAGCATGTC TGTTGGAATTGTCCAGGGAAATGAGGGAGAAAAAAAATTTACTTTCACATTGTAACTTTC GTGGGCCCTGGGTGCTTTTGCCTTTGTAGATTCCTTATACTATAAAAAAATTAAAAATTA AATTTCATGACTACCCTGATATAAAGATGAATGCATTAAAATGATGTATGAAAATATTTT CTTCTAACTAAAAGTGAGTTTTTTTAGGTCTGAAGATTGTAAAAGACGTAAAAATATTTT CATGGGCCCCTAAAAAGTGTTGTGAGCCCTAGGCACTGTCCCTGCGGTACCCAATGGAAA AGTCAGCCTTATCTACTATTGTGCTTTTTGAGGCTGGGAAAACTTAAGAGTTTTTTGACT TATAATGGGAAAGACAGCATTAGTCATGCAAGGCCTATTACAGGAAATATAATTCTTAAA GTCCATCTTGTAATTTAGTGAGAAATTAGGAAGCTGTTTTAGATTTTTTTCCCAGAAATA TTAATTTAGTCACTGAGCTAGATAGCCTATTTAAGAAAAAGTGGAATTAAAATAAATTAT AATGTGCTTTCTAGATGAAATAAGAATTTTGCTCACTTGCTTTTCTCTCTCCACATTAAA CACCAAACAGGTATCCTGATGTGCAGACTCGAGTGCAGGCAGAATTGGATCAGGTCGTGG GGAGGGACCGTCTGCCTTGTATGGGTGACCAGCCCAACCTGCCCTATGTCCTGGCCTTCC TTTATGAAGCCATGCGCTTCTCCAGCTTTGTGCCTGTCACTATTCCTCATGCCACCACTG CCAACACCTCTGTCTTGGGCTACCACATTCCCAAGGACACTGTGGTTTTTGTCAACCAGT GGTCTGTGAATCATGACCCAGTGAAGTGGCCTAACCCGGAGAACTTTGATCCAGCTCGAT TCTTGGACAAGGATGGCCTCATCAACAAGGACCTGACCAGCAGAGTGATGATTTTTTCAG TGGGCAAAAGGCGGTGCATTGGCGAAGAACTTTCTAAGATGCAGCTTTTTCTCTTCATCT CCATCCTGGCTCACCAGTGCGATTTCAGGGCCAACCCAAATGAGCCTGCGAAAATGAATT TCAGTTATGGTCTAACCATTAAACCCAAGTCATTTAAAGTCAATGTCACTCTCAGAGAGT CCATGGAGCTCCTTGATAGTGCTGTCCAAAATTTACAAGCCAAGGAAACTTGCCAATAAG AAGCAAGAGGCAAGCTGAAATTTTAGAAATATTCACATCTTCGGAGATGAGGAGTAAAAT TCAGTTTTTTTCCAGTTCCTCTTTTGTGCTGCTTCTCAATTAGCGTTTAAGGTGAGCATA AATCAACTGTCCATCAGGTGAGGTGTGCTCCATACCCAGCGGTTCTTCATGAGTAGTGGG CTATGCAGGAGCTTCTGGGAGATTTTTTTGAGTCAAAGACTTAAAGGGCCCAATGAATTA TTATATACATACTGCATCTTGGTTATTTCTGAAGGTAGCATTCTTTGGAGTTAAAATGCA CATATAGACACATACACCCAAACACTTACACCAAACTACTGAATGAAGCAGTATTTTGGT AACCAGGCCATTTTTGGTGGGAATCCAAGATTGGTCTCCCATATGCAGAAATAGACAAAA AGTATATTAAACAAAGTTTCAGAGTATATTGTTGAAGAGACAGAGACAAGTAATTTCAGT GTAAAGTGTGTGATTGAAGGTGATAAGGGAAAAGATAAAGACCAGAAATTCCCTTTTCAC CTTTTCAGGAAAATAACTTAGACTCTAGTATTTATGGGTGGATTTATCCTTTTGCCTTCT GGTATACTTCCTTACTTTTAAGGATAAATCATAAAGTCAGTTGCTCAAAAAGAAATCAAT AGTTGAATTAGTGAGTATAGTGGGGTTCCATGAGTTATCATGAATTTTAAAGTATGCATT ATTAAATTGTAAAACTCCAAGGTGATGTTGTACCTCTTTTGCTTGCCAAAGTACAGAATT TGAATTATCAGCAAAGAAAAAAAAAAAAGCCAGCCAAGCTTTAAATTATGTGACCATAAT GTACTGATTTCAGTAAGTCTCATAGGTTAAAAAAAAAAGTCACCAAATAGTGTGAAATAT ATTACTTAACTGTCCGTAAGCAGTATATTAGTATTATCTTGTTCAGGAAAAGGTTGAATA ATATATGCCTTGTATAATATTGAAAATTGAAAAGTACAACTAACGCAACCAAGTGTGCTA AAAATGAGCTTGATTAAATCAACCACCTATTTTTGACATGGAAATGAAGCAGGGTTTCTT TTCTTCACTCAAATTTTGGCGAATCTCAAAATTAGATCCTAAGATGTGTTCTTATTTTTA TAACATCTTTATTGAAATTCTATTTATAATACAGAATCTTGTTTTGAAAATAACCTAATT AATATATTAAAATTCCAAATTCATGGCATGCTTAAATTTTAACTAAATTTTAAAGCCATT CTGATTATTGAGTTCCAGTTGAAGTTAGTGGAAATCTGAACATTCTCCTGTGGAAGGCAG AGAAATCTAAGCTGTGTCTGCCCAATGAATAATGGAAAATGCCATGAATTACCTGGATGT TCTTTTTACGAGGTGACAAGAGTTGGGGACAGAACTCCCATTACAACTGACCAAGTTTCT CTTCTAGATGATTTTTTGAAAGTTAACATTAATGCCTGCTTTTTGGAAAGTCAGAATCAG AAGATAGTCTTGGAAGCTGTTTGGAAAAGACAGTGGAGATGAGGTCAGTTGTGTTTTTTA AGATGGCAATTACTTTGGTAGCTGGGAAAGCATAAAGCTCAAATGAAATGTATGCATTCA CATTTAGAAAAGTGAATTGAAGTTTCAAGTTTTAAAGTTCATTGCAATTAAACTTCCAAA GAAAGTTCTACAGTGTCCTAAGTGCTAAGTGCTTATTACATTTTATTAAGCTTTTTGGAA TCTTTGTACCAAAATTTTAAAAAAGGGAGTTTTTGATAGTTGTGTGTATGTGTGTGTGGG GTGGGGGGATGGTAAGAGAAAAGAGAGAAACACTGAAAAGAAGGAAAGATGGTTAAACAT TTTCCCACTCATTCTGAATTAATTAATTTGGAGCACAAAATTCAAAGCATGGACATTTAG AAGAAAGATGTTTGGCGTAGCAGAGTTAAATCTCAAATAGGCTATTAAAAAAGTCTACAA CATAGCAGATCTGTTTTGTGGTTTGGAATATTAAAAAACTTCATGTAATTTTATTTTAAA ATTTCATAGCTGTACTTCTTGAATATAAAAAATCATGCCAGTATTTTTAAAGGCATTAGA GTCAACTACACAAAGCAGGCTTGCCCAGTACATTTAAATTTTTTGGCACTTGCCATTCCA AAATATTATGCCCCACCAAGGCTGAGACAGTGAATTTGGGCTGCTGTAGCCTATTTTTTT AGATTGAGAAATGTGTAGCTGCAAAAATAATCATGAACCAATCTGGATGCCTCATTATGT CAACCAGGTCCAGATGTGCTATAATCTGTTTTTACGTATGTAGGCCCAGTCGTCATCAGA TGCTTGCGGCAAAAGGAAAGCTGTGTTTATATGGAAGAAAGTAAGGTGCTTGGAGTTTAC CTGGCTTATTTAATATGCTTATAACCTAGTTAAAGAAAGGAAAAGAAAACAAAAAACGAA TGAAAATAACTGAATTTGGAGGCTGGAGTAATCAGATTACTGCTTTAATCAGAAACCCTC ATTGTGTTTCTACCGGAGAGAGAATGTATTTGCTGACAACCATTAAAGTCAGAAGTTTTA CTCCAGGTTATTGCAATAAAGTATAATGTTTATTAAATGCTTCATTTGTATGTCAAAGCT TTGACTCTATAAGCAAATTGCTTTTTTCCAAAACAAAAAGATGTCTCAGGTTTGTTTTGT GAATTTTCTAAAAGCTTTCATGTCCCAGAACTTAGCCTTTACCTGTGAAGTGTTACTACA GCCTTAATATTTTCCTAGTAGATCTATATTAGATCAAATAGTTGCATAGCAGTATATGTT AATTTGTGTGTTTTTAGCTGTGACACAACTGTGTGATTAAAAGGTATACTTTAGTAGACA TTTATAACTCAAGGATACCTTCTTATTTAATCTTTTCTTATTTTTGTACTTTATCATGAA TGCTTTTAGTGTGTGCATAATAGCTACAGTGCATAGTTGTAGACAAAGTACATTCTGGGG AAACAACATTTATATGTAGCCTTTACTGTTTGATATACCAAATTAAAAAAAAATTGTATC TCATTACTTATACTGGGACACCATTACCAAAATAATAAAAATCACTTTCATAATCTTG OMIM ID 601771