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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP4B1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1580 Official gene symbol CYP4B1 Full name cytochrome P450, family 4, subfamily B, polypeptide 1 Aliases ,CYPIVB1,P-450HP, Gene summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 1   Locus: 1p34-p12 Gene position 47264670 - 47285021  Map Viewer Gene orientation plus Gene size 20352 bp Gene sequence >CYP4B1:17236588..17256939:Length=20352 AAGATGCATGGGTCCAGAGTATAAAGGAACCCAGGAGCAGCTGAAGGCAGGTCAGATGAA GGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCC TTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCACCTG CTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCAC TGGCTTTTTGGACATGCCCTCGAGGTATGTGGAGGTCGGGAGGGTGGGGGAGAAAGAAAA CATCCTCCCTCCTTTCAGAGAATCAGGCCTAATTCCCAGGGGGCTGTGGAGGGAGACTTC AAACTTGGGCAGGGGGATGATGTCCTGGGATCCATGGCTTCCATTCAGCTTTCCCACCGG AATTTCTCCTTCACTCCAGCCTTTCAAGCTGACTTCAGAAGTGGGGGCAACTTCCAAGTC AGGGCTCAAGCATGGCACAGACACCTTCTCCTCATTCTGAGGCCCAAAGTTTGGACCAGG TTCTGCTAAAAGCTCAGCAATGACAGAAAGGCAATGGCAGAAATCCAAAACCTCTGGATA GTACATAGAAGTAGGCAATCCATTGAAAGCTCAATCAGCGTCCGTGTTGTTGTGTGTAGT GTAAAGATTTCCATTTGTAAGGCAGGAAATGAGAGTGAGCATGAAGATGAGTACCGCCAC ATGACAGACCTCACCGAGTGTCTAAGCGGTTGGTGTCCCCAAAGGCAGGGCTCTCCCGGC CATGCCTATGGGTGGCTCAGGAGCCGTGACACCTTCCCAGGTTCAGATCATGGTTCGTCT TCCTGTTACTCCAGGGTGGGAACCACCTTAGCCCCTGCTCTCAGGAAGATCTCTTAGTTT CCTACTGTATTGGGGATCTAGACCAGAGGTTTCTAATTAGACACAGGGCAGGGAATTGGA ATCAACTGGGAGGAGCAAATTCCTGGACCTCCAGTTCCTGGAGATTCCAATTTGTCAGAT TGGAACTAGGAGTTTACATTTATAAACCTGTCCAAGTGTTAGTGTTTTGATCTGCAGCCA GCTTGGGGAATCCAGGTAGAGATGCCAGAGACTTTTCTTTCTTTCCCTCTCTTTTTCCTT TCCTTTCCCTTTCCCTTTCTTTCTTTCTTTTTTTCTTCTTTCTTTCTCTTTCTTTCTTTC TCTTTCTTTCTTTCTTTCTCTTTCTCTCTTTCTTTCTTTCTTTCCTTCCTTCCTTCCTTC CTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCTTTCCTTCCTTCTCTT TCTCTCTCTCTCTTTCTTTCTTTCTTTTTTTGATGGGGAGTTTTGCTCTCTCTCCCAGGC TGGGGTGCAGTGGCGCAATTTTGGCTCACTGCAACCTCTGCCTCCCAGATTCAAGCAATT CTCGTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGCACGCGCCACCATGCCTAGCTAA TTTTTGCATTTTTGTAGAGATGGGGTTTCACTATGTTGGGCAGGCTGGTCTCAAACTCCT GACCTCAAGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCA CCGCGCCTGGCTGACATGCCAGAGATTGAGGCTCAGAGTGAGGCAAGTTCCTTCTCCTAC CTTCTGAACTCACTTTCCTCATTCTCAGTCTGGATGGGGGCACTGCTTCTCTTCCTTGAT TGACACTAGAAATGAGCTTGACCTCTAGGCTTATTCTTGCCCTGACAGATAACCCTGTAA CATGCATCCTGAAGACATCCAGGAAAGGAAAGTGTGGGTCAGAGAGATGAATCAGACCCA GGCCTGGGGTTCAAAGAGCTTACGGTCTGAAGGGAAAACAGACACCAGAGCCTTGCTCCC GAGCTGGGCGAGGTTCCTCCCCAGGATTCTGCCTTAGCCGCATTATTTTGATCTCAGCAC CTGTCCTGTTGGATTGAAGTCTTCTGTTTACCTATTCAACTTCTGCACTAGACTTTGGCT CCTGGAGGATGGAGATCTGATCTGATTCATCCCTGTACCCTCAGGGTCCAGCATAAAGCC TAGCATAGTGTAGGCATCACTAATGAACCAGTAGTGAATGTTGGAGGGTAGGGAGAGTAT CCACAGAGGAGAAAGCATGAGGGAGAAGAAAAGCAAAGGGACCAGGAGGGCTTGGGAGAG GCTTTGCTAAGTACACAAGAGGGCCAAGGGAAGGTTGAGGTCTGACGCTAAAAGGGTACA AGAGGTATTTAGAGAGAACTTTCTCCCTTTCTTCTTGTTCCCTCTCCACTTCTACCTGCC TTCGTCAAAGTTGTGTTTGCCCTCAGCCAGGGACTTCTTTAGGACAGGGACCTTGCACCC CCACCTCCATGTCAGAGCTGGCTGTTTTCTTCCCCTTAACGGCCCCCACCCCCACCTTGA GAGTATGCAGAGGGCCTGGAACACAGTCTAGCTTTGGCTTCTTGGCTCTAACACAACTGT CTGAAGGGCCTTCTCTTGGCATCAGGTTGAGCAGACAAAGGCTGGAGGAGTGACTACTTG TGGGAGCTACAAAGGTTTCCTGGGGAACCATTGCAAGCACAACTCCTGCAGTCCTCAAGG GCTTGGCACCTCTGTTCTTGCCTGGATTCATACCTGAACTTGAGAAATGGGTTGGGCAGA GAGGGGATTATTTTCCCTAATGTAAAAATGAGGACATTGAAGTTCAGAGAGTGCAAAGTA TTTGTCTATGTCTGTTTAGTAGCTCAGGAGTTAGGTCGAGACTGGGCCCAGGACTTCTGC ATTTTAATTCGTAATGTTGTCAGACCATAAAAGGTTACTGCAAAGTTGATTCTTAGGCCC AGCAATGATGGGAGTAGGAAGGGGAGGAAGACTGATGGGTAAAGGGACTGGGGGCAGGGA AGAGCTGTCCGTCAGGATTAATTTCTCCTTCTTGGTCTCTGATTACAGTCTGGAGGCCTT GGTAGCATCTACCTGTCATCCTCCTCAATTCTCAGAATGTGTCTTCTGGAGGTGGGGACA TGTCCTATTCTTCCAGGGTCCCCCTCATTCCAGTCTAGGAACCAGGGAGGACTTTGCACA TAGTAGGTGCTCAGCTATATTGTTGGCCTGAGGTTGGAACCCTTGAAAGAAGCCAACAAA TTGGTGTGTGTGGGTGTGTGTGTGTGTGTAGAATGCCAGCTCCCAGATCAAGGAAATGAG ATACTCTGAGACTGCAGAGGCCTCTTTCCCAGCCATGCCCTTTGCTGTGAGAGTGCCCTT GACCTTGTGCTGTGTAGTGAAGACAGGGCTGTGGCTCATTTTCATTCAGTAAACATTGAT TACAGGCCTTCGCTGTGCCCAGTTAGCTAAGCCACTTTACCTCTCTGTGCTTCTGTTTCC CTGTCAACAAAGTGGAGATAATCATTTTTACCTTACTGGGTTAGAAGGGGATAGAAAGAG ATAAAGTATAGGTATTTTGCAAACTACTGGGCAGATAAACGTCAGGTGTTAAATCATCAT AGAGGGATTCTTGCTACAAAACACCCTGGGGCATTTGCTTTCTTCATCCCCTTCCTTCTT CTCAAATCAACCCAGTCTTTGTGAACCAGATATGGTCCCTCTTTCCTAAGCAACCAGCAG TGTCTGATCAACAACTCTGGGTCTGGTCCTATGCTGAGGCCAGAGGATGAAGAATCAAGA CAAAGAGCTTGCCTCAGAGGAACTAGGTCTGTAGGAGAGATGAATAACACAGCACATGTG TTACCAATCTTTGGGCCTAGAGAAGGGCCCCTCTCGGCGTGGGGAGTCAGGGAAGGTCCA GGGAGGTGATGCTGAGGCACATTCTCAAAGATCTGGAGGTAGAAACCTGTGGCAGGAAGT GCAGAAGAAAAGGCAGAAGGTGCTCTCTGTGCAAAAAGGCACACAGGCTGGAAAAAGCAG TGTGTTTAGGAAATTAAATTGTCTTTTGGGGTCTAGGACATACCTGTGTTAGTACCTCAG CGCTTCTGCAGTGGTGACAGGGAGGACAGAATGGAGAGGATGAGGCTGGAGGTAGACGGG GCAGTCACACAGATCCTTGAGGCCAGGTCAAAAGGCTTTACCTTATTTTGAGGACGATGG GGAATGATGGAAGGAATTTAAGCAAGGGAGAGACAAGCTCAGACTTATGTTTTAGAAAGA TCACTTTGGCTTCAAGGTGGCGAACAGATTGACAGAGGGCAAATAGGAGGCAGGGAGGCT AGGGTGGAGGTGATCCAGGCCTCCACCTTGTGTTGGGGAGTGAGCCAGTGGGCTGGAGGA AAGTGGAAGGTAGGGCAGGCCAGGTCTTGGCATGGTAGCCACAGGAGAGAGAGGCGTTGA GACCTCCACCATAGCCAGATGTGAGGGTCAGTGAGGGCTCCTCCATGTAGCAGGAAAAGG AAACAAGGATTACCCTTGGAGCTCTGTTAATTGGAGGCATCAACACAGCTGGACTAGAGC AGAATCTAGCGAAAGTCATCAAAGGAGAGCCATAAGACTGGATTGTAAACAGGAGGAATG AATTTCTATGTCTCAATTTTAAAATGTGGGCATCTGAGACCCAGGAAGAGGAGGCTCAGT GGTGGGCAGCACTTGTCAGTGTCTGGGTATGGGATCCTCGAGTACTGGTTTTGGAGAATT CCGTGGCAGAGTCTCCTCCCATGACCTGCTACATCTGGTTCTTTTTGCTCTGGTTTGCTG ATTTCAATGTAAAAATCACTTGGTGGGCCTGCAGGGAGGAGGGGCTGCCTCCACAGGGCA TCCCTCTTCATATTGATATAAACCATGGAGAAAACGACATTCCATATTCCTGGCTAGTTT TTGGGTGGGTGATGGTACCATCCCCAGGTTCAGTAGGAGAGGCAGATTTTGGGGACAAAA GTGTACGAACATGTGTATGAGTGTGGGTTTGGAAATGCTGGGTCTGAAGAATCTGGAGGG TGTCATGCAGAGAGTTCCGGGGGTTGATTATGATTCTGGACCTCAGGAGAAAGGTAAACT GGAAAGAGCTGTCAACTGAGAAATTGTTGGTAGGTAGATGGCACAGGAAACCACAGAAGC AGGTGAGAGCTTTCAGGGAGAAGACGCAAGGGAAGAGGCCAAGGACTGGATCTGGAGGAA CAAAGAGTGGGTGAGGAGCTGCCCATGGCAGCCACTGGGAGAGAGGGGAGGACATCCAGG AGACAGTGCATGAGAGACAGGGAGTCAACTGGGCTCAGCGCCAGGGAGGGTGCTGGATTC CTTAGCAAGATCAGCATAGGAGAGGTGGGGCCATCACAAGGAATTGGAAACAGTGGGCAC AGCTCTTTAGAGAAGTTAGATTATGAAGGGATGAGCAAATAAGGTGTTAGCTGGAGGAGG AAGCTGAACAAAGGGAGGTTTGGTTTCATTTTCTTTCTTTTTTTTTTTTTTAAAGTGAGA GACTTGAACAAATTTTGAATGAGGATGGGAAGGAGCCTGCAGAGAGGGTGAGGTCTGTGA TTTGGGAGAGAGGGGCTGATTGATGGGTGAGGTGCCTTGTGGGGAGGGTTGGAATCCAGA TGGACTGGTCTTGGACAGGCCCTGCATGCTTCTCTCCTGAAACAGAGGGAAACAGAGAGG CTGGGTGCAGGTGGGGTGGTCCTTCAGGTCTGCCAGCTGACTTTTTGGGGTTTCTTATCT GATGGTTTCTATTTTCTCTGGGAAGTACAGCAAGGGTGATCTGCCAGGAGTGAGGAGGGG AGAGGTAGAGAGGGCAGTTGAAATAAAAGTTTTTGAGAAGCAGATTGTGGCTGATGCCAT GGGGCTTTCCAGAAGGCATTTCTGCTGATCTTTGCTGAAATGTCACCTTAGAGTGGCCTT CCTGACCCACCCCCATCCATAGTGGCAGCCCTGCCCCTTACTCTGCTTTTTTTCTTTCTG GAGTTATCACTACATGAAATTGTATTCTTGGTGTATTTGATTCTTTTTATTTTCTTTCTC CCCACTTGGAATGTATGCTGGTGGGGCAGGGCTTTGTCTTGCTCACCACTGTAACCAGAA ACTAGCACTGTCCCTGGCACAATGCCCATGTGTTGGAAGAGTGGATGAATCTCTGGGGGG AACCAACTCTGGGCAGCAAAGCCACCCATGCGGACTGAGGACAGATGACTGCATCCCCTT GGACTCTTGGGCATTTCTTGGGTCCCTGCCTTCCTGCCTTTTTAGCTGTTTGGATGTTTT CCTGCATTCCTCCTCTCATCTGATTGGGTGCTCCTGAGTCTGGAGTTCACCTTTGGATGC TGAAGACAGGAGGGATGTTGGGGGCAGAGCACAGGCTTTGGAATCTAAAGACTGGGGCAC GATGCTAGTTGTGTGACTTTGGGCAAAGCCCATCATCACTTCCTAGCCAAGGCATGGTGG CTAGAGAGTCCTGGTGACCACACTGATCTCACCCAAAGTCTCTTTGCTCCTTCTATTGAG CTAGGGGTTCTTTCTGTATGTTATCTGTTCACATGTACATGTGTAATGGTTTATTTGTCT TTGAAAGGGAGGATGGAGGATGAAGTCATGTTTGTCACCAGCATGGGAGGAAGTCACCTC TCTGCTCCCTGGGGTATTTTGCATTCGATCCCCTCTTTCCAGGCTCTCCATGGCTCTGTT CAACCTCACAGCTGAATCCCCAATGAGTTTTTGTACATTGAGTCTGCTTTTCCCACTGAT TTTTATAGTTATTTCAGAGATGCTACATCTTCTCCCTTTTGGTTGTTTTTTTCTTGGCTT CTAGCTCTTTAGCTTTATTTAAAAGCTTGGCAGTGGCTTGGACTCATGCACACATGGAGC TCTGGTAATTTTGGGGTGTGGGGAGAGGGCCCATAGTAGGGAGACAGCTGAGACTAGGGC ACCAAAGGGCACCTAAGGGTGTCCATCCTGAAGGAGAGCAGTCCTAGGGGGTTCTAGCCC CCAATTCCCAATCCCTGCAGGACTTCCCTGGGCAGTGGGAGCCTGTGTGGTCCCAGAGGG AGACCCATGGGGAAGGCTATGGGCAGGTGTCTTTCACTTTAGCGACTAAGAAGCCTTTTG AGGAATTAAGACTGTCCAAAGATGGTTGGGGTATTTTGAAAAGAAGTTTCCTGTCACTAG AGATGTTTGAGCACTTGGGCAGGGATTCTTACTGGGTGAAGGTGCTGGGCAGGCACCCTG TGTGCTGGGAATCCGAGACCGACATGACCTGCCTTGAGGGAACTATGACATGCTGCCGAA AAGGAAACCCCTTCGTCTTTCTCCTCCCTCACCTTTTGTTTTTCGAAACTCTTATCCCCA TTTTGTGAGCAGACTGATTTTCATTCTGAAGCAGCCCCCTGGGGCACTGTAGCTGCAGCA CACTGGTCAAGGGTAGCTTGTTTCTTGGACACTGGCCCACTGAGCTTCGGGTCAACTGGC TGATGGCTTGAGCAGGCTTGCTAACAAGGGCTGCAGAAAGAGACTAAGCCAGGATCCCTG GTCTCCCTTAACTCATGCTGGACTGTTCCCTTTGGTCTTTGTACCGCACGTTTCCACCTT TAAAGAGAGGTCAGGGTTCCACTAGGCAATGTTGAAATCCTTTTCCGATCTGATTCTTGG AGCAAAGCTTACTTTAGGCTCTTGAGAAGCAGAGAGGAAAGTGGTGACGTATGCTTGCTC TTCCCAATCCCTCCAGTGGTTTATTTCTGGTGAGGTCAACAAGGAGTGCCAATGTGAGGG TGGGAGGTGGGGCTGGGGAGCTGGGATCAGTGAATTATTTTCATACCCTGCTCTCTTCCT GTTTCCTTCCTTCTGGAGAAAAAACAAGCCGTCCCAGAACTTCCAGTCCTGTAAGTGTCC CAGCTCAGGCATTCTGAGGGCGAGTCTGAGGCATGCAGTTGTGTAATCCAGAGGAACTGT CCAGGCAGTCACGTGTACCCCACAGGGAGGATGCCTCAGCCCTCTTGAGGGGCTGCAGCT GCAATAGTGGGACCAGGTGCTGGGAGCTGTCCTCCTTCTTACCAGGCTCCCGGGGTAATC AAGGCAGGTGCCTGGCAGGTGCTTCTAGTTCTCTAGCTTTATTTAAAAGTTTGGCCATCG CTTGGGCTCATGCACATGTTTTTTATTTATCTTAGTTTTCTTTATTTCTTAAATAAATCT AAAGAGCTAGGAGAAAGCTGGGCACAGGGAGGCAGTGGCAAGCTGGCTGCGACCTCGATC AGGGCACAGGTTGTGAATGTGGTCAGCATGAGACCAGGGTCTACTGTCCCTTGTGGGGTT GCTGCAGAGGTGCACAAGCATAGCTGATAAGGAGGGAAGTGGGGCTTGGATGAACCAGAT CAGCCAAAGGCTCCTTCCAATCCTAAGATCCTATGAGTCTGGCTTTTTTGTGACTTAAGC CTTTCCTTGACCCATCCAATTGGGCTTTCTGGACCTGGTAGGGATGGAGAGAAGGGGAAT GGCCAGGTGACCAGGAAGTTGGCAAGGAAAACCCAGGAGGGCAGATGGAAAAATAAGACA GACACCAGGGAAAGGAGCACTTCCAGGGATACCAGCCAGGAGGGAGGCAGGCATACAAGA ATGTTTCCCCTTGCCTGTGGGTGGAGATGATTTTTATCACTTTGTGTTCTTTTTGACATC GTGTACTCAAGGGCAGTGAAAACTCTTACAGCCCTGTTGGGTTGAACTCAGGATTCTGCG TTCAGAGGCAGTGAGGGAAGGGATCAATGGGATGATTACAGACGACTCCACAGAGGGCCT AGGAGGGGAAGAGCCCTAGAGAAGGCACAGACGGGTGGCTGGAGGCCAAAATAGGCCCAA TCCCATGAGCCCTTGGAGATAGTGGCTTGGGCCAGAAAGGATCCCTGGGGGCTACATTAT CAGATGCCTGTGTCCTTCTTTAAGAATGTTCCCTGGAAGATACAACATGGATGTCTTAGT CCTTTGTGTTGCTGTAAATGAATACCTGAGACTGGGTAAAAGGTTTATTTGGCTCACAGT TCCACAGGCTGTACAGGAGGCATGGTCAATATCTGCTTCTGGTGAAACTGCTATTCATGA GGAGGAGCTTTAGGAAACTGCTATTCATGAGGAAGAGCAGACATCACATGGCAAGAGAGG AGGAAAGGAGAAAGAGAGAGAGAGAGAGAGAGGTGCCAGACTCTTTTTAACAAACAGCTC TCAAATGGTATTTCTAGTTCTAGATCCCTGAGGAATCGCCACACTGACTTCCACAATGAT TGAACTAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTATTTCTCCACATCCTCTC CAGCACCTGTTGTTTCCTGACTTTTTAATGATTGTCATTCTAACTGGTGTGAGATGGTAT CTCATTGTGGTTTTGATTTGCATTTCTCTGATGGCCAGTGATGATGAGCATTTTTTCATG TGTTTTTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGTCTGTTCATGTCCTTCGCCCAC TTTTTGATGGGGTTGTTTGTTTTTTTCTTGTAAATTTGTTTGAGTTCATTGTAGATTCTG GATATTAGCCCTTTGTCAGATGAGTAGGTTGCGAAAATTTTCTCCCATTTTGTAGGTTGC CTGCAGCCCTCCCATTACTGGGTATATACCCAAAGGACTATAAATCATGCTGCTATAAAG ACACATGCACACGTATGTTTATTGCGGCATTATTCACAATAGCAAAGACTTGGAACCAAC CCAAAGGTCCAACAATGATAGACTGGATTAAGAAAATGGGGCACATATACACCATGGAAT ACTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAATTGG AAATCATCATTCTCAGTAAACTATCGCAAGAACAAAAAACCAAACACCGCATATTCTCAC TCATAGGTGGGAATTGAACAATGAGATCACATGGACACAGGAAGGGGAATATCACACTCT GGGGACTGTGGTGGGGTGGGGGGAGGGGGGAGGGGTAGCATTGGGAGATATACATAATGC TAGATGACGAGTTAGTGGGTGCAGCGCACCAGCATGGCACATGTATACATATGTAACTAA CCTGCACAATGTGCACATGTACCCTAAAACTTAAAGTATAATAAAAAAAACCCAAAAAAC AAACAAAAAACAAAAAAATAAACAATATGCAAAATCCTTAAAAAAAAACAAAACAAAACA AAACAAAAAAAAGCTCTCATGGGAACTAAGAGAACTCACTCAATCCTGCCAGAATGGCCC CAGGGCCATTCATGAGGGATCCACCCCTATGATGCCAACACCTCCCATGAGGCCCCACCT CCAACATTGGAGATCAGATTTCAAAATGAGATTAGGAGGGGACAAATGTCCAAATTATTA AGGTTTGGACATTTTTCCCTTCCTAATTTGTTTGGATACTATCAGTGAATAGGTGGCAAT TGTGAGAGAGAATTTTACGGAGAGAAAAAGCAGGCCCAGCACAGGCTCAGGCCTCAACAG GAATTTTATGGGACTGTAACCTAACCTCTCTATTCCTTAGGCTCCTCTTCCCTAAAATGG GACCACTTAGAGTTGTTGTGAGGATTCAATCAGGTCAAAATGTAAGGTGCTTAGAACAAG GTCTAGCACACAGCAAGTGCTTAATAAAGATTAGTCATTACCATGCCTCCCCACAAACTC CAGAGCTTGGACCTTTTCCAAGGCCCCTGGGCAGGCCACTAGGAGTGTTAAGTGTATCTT TGAAAGACTCCCACTAAATGGGGAAAAATAGTTAAATACATTATGGTACATCCTTATAGT GAAATACTACACAACTGTTAAAAATAGTAATGACAGTTAAGTGCACTAGCTTGGAAAGGA GGACAAGTTATGTTCAATGAAAAATGGCTGGTTTTGCAAAAATATTTATTGTATAACTTC ATTTACTTAAAACACCTCTGGGTGAGTAAACGTGACTAGAAAAACCTCCAAAGGACATGT ACCACCCTCTGGATGACCTATTCAAGCTCATCCCAGGTGACTGTCCCACCATGGGGCAGC TCCTGGAAGACACCATGATCTTTCCCAACCCAGCGCGTTTGTGCTTTCTGTTTTCTCACC TGGAATGCTTTTCCTTTATGCTTCACATGGCCAGAGACTCACCATCCTTCAAGTTTCACC TTAAATGTTGTCTCCAACAAGAAGCCTTCCAAGATTACCCTATCTAAGCAGGCCCTCCCT GTTAGTGTCTCTCATAGCACTGTTTTTATTCTGAGCACTCACTATTGTCTGTGATTATTT TACTTAATTGTCTACTTGTCTATTATCTGTCTTCTCCATAGAATGAAAGGGCAGAACTTG TCTGTCTCATTCCCCTGAGATGTCTAGAACAGAGCCCTGCACATGTAGGCCCTCAATAAA AATGTGTTGAACGATACGGCAGGGGTGGAATTGAGGCCATTTCTCTATTGCACAATGAGC AAATATTACCTATCTTTATAATTAAAGAGCTTTAATGTGGAGAAGAAAGCACTTTCTGGC TGCAGTGCAGTAGAGAGTTGGTGGCAGGTGCTAAATGGAAGCAGGTTGGCTACTTTGGGG ATGTTGAGCTAACCCCGGTGTGAGAAGAGGGCGGCTTGGAATTAGAGCAGTGGTTGTGGG GCTGGAGAGGGGACTAAGCCCAGGGATGTTTAGGAGAAGAGGGTGCAGGAGAGGTAAGGA AGCAACCAGGGCCTGCCTGGGCAGCCTTCTCCCCTGCCCTCCCAGGGACTTGGGGCCTAG CTGGTGACAATGTGTTCCTGAGTGACCTTGGCCTTCTGTCATCATTTCAGATCCAGGAGA CGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCT GGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGT ACAGCCGTGGGGGTGAGGAGAGAGGATGGGGATCTCAGGAGAGGGTGGGGCTTCCTGAGA ACAAAGGGCTCAGGGCATGATATGGGGAGGAAGCCTGGGCCTGTGTACTAAGTCTGCGGA GCTGAGGTTCCCACCCTACTCATAAATGAGCCTCCTCTAGGAACCCCGGGTCCCTGCTTG ACCTGATTGTCTCCTCCTGCAGACCCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAG TGGATTGGTGAGTGAGCACCTGCCTTCCCTGCCCTGCCAACCTCAGACCCGTGGTGCTGG GTGACTAGGATCCTGGCCTGTCCCACTCAATTGGTTATCCCAGATGGCCTAGTTCTCGGG TGCCCATCCTAAGCTCAGCTGCTCAGTGGAGAGACAAGGGAGGAGCAGGAGAGCCCCCAG CTGTGGGGCCAAGGCATCTTCTCTGGCAGGGCCTGATTCTCTAGACAGGGCAAAGGCTTT GGAGAATGTGTGAGTGCGAAGAACAGTTTCCTGAAGGAGGTGGCACTAGAGTTGATCCAA AAGGAGATTTAAATAGGTAGTGCTGGCCAGGGCAAGGGCCTAAGGAAATGGTGTGGTGGT AGGACCACGGCTGGTCACCAGAGGCTGTGAGGCTGTCGGGGTGGCTACAAGGCAGAGCCC AGCTTGGAGATGATGCTGGGCAGGGAGGACAGGCCAGCCTTGACTGCCAGGATAAGGAGG TGATTTGATGTTGAGAGTAGGTGGGAGTCATTGAGTATTTTATTTTATTTTATTTTACTT TTTCCTTTACAGAGGTACTCAAGTTAAAGCCATTGAGTATTCTTTAGCCAAGGCCATATG CTTCTCCAAAGCTCCTCTTTTACTCATGATCCTATGGTGTCTTCAGCGTTTTCCTGGGAG CTGAGAAAGGGCAGGGCCAAGAGGGAGAACACATTCCCAATCCTATTTACTCACCGAGTA CCACTGGGAAGACTTTTTGCTTCTAACCCTCTTTTTAGTTATCAATGGGAGGATAAAATT AGAAGGCAGACAGAAAAGGGTTAGGAAAATGAAGAGGTGGTTTTGAAGACAGGAATGCAT TTCCATTGCTGGGTGTGTTGGAGTGGGGTAGGAAGGGTCCCACCTGAGGCCATGAAGCAC GAACACGGTGGGACATTCCCTAAGTCCTGAAGCTGTGGCCAGTCTCAGCAGCTGAGAGTC AAGGCTCAGCAGGCTCCCCCTCTGCTTGGCTGTCCCCAGGGGGATGCGTGTCCTTTGTCT CACATCTGGCAATGTCATCTGACACAAGTTCCTGGACCCAGGCTTTGTGGGTGCAGCTGA GATACAGAAACTGAGTTATCCTGTCCTAAGGAAGGAGCTCACTCAGCCAAGAACTGCTGC CACCTGTCTCCTGAGGTCCTGGTAGCCTAGGGTGAGGGCATGGAGGGCAATACTGGGTCG CTTAGTGGCCCACCCTTGGAGGGTTCCAGGCTCAGGGATGGAGTCGTGTAGGATGTGCTT AGCCCCAGGCTGCCAGGGCCTGGACTGACCAGCCCTCTCTCTCCCATCCCTTCCCCAGGG AGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCT GGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATC ATGCTGGTGAGCTCCCTGTGCCAGAGTACTGGAGGCTGTTGCCTGCTGGGCTAGCCCCTC TCCACCCTGATTTTGTCCTGGGGAGAGTAGGTGGTGCTCTGCAGTAAGGAGAATAGCTGA GCCCCAAGGCCTGTTCTGCCTGCAACAGCAGTGCCAAAGCCCTGCTCTACTGACATGTGC CGCAGGCTGCCACTGAGTCGGTGCTGAATCTCTAAGTGTCCTGGCAGCCCGATCCTTGTC TCCACCAGGAGACCCAGCCCTCTTTCCTCCCAGGCCAAAGGGTCTCTGTGAGAACTTAAT AAGGCTCCTAGCATAGCAGGTTTGAGGACTGCCTATATTTGAGAGTATGGGGAAAGGCTT TCACATCTAAAACGTGTCTCCTCATTTTCTGTCTACCACAGCTGCCCAGAATTATGTCAA TACAACTCATCTCTAAGAGGGATGTCAGAGGTCAGGGTTAGAGTCTTAGGGCTGGGTAAT CCCTAAGTTATCCAGGCTAGTCTTTCCCCTTGTAGGAAACTCCCCTCCAGGATTACTTAC ATATACACCATGCGGGGGAGCTCACCACCTCTCAGCCATCCTACTCCCTTATAGGCTGCC CTGACTGGGAGAAAACGTCTGTGTGCTGTGCAAGATCTGCCTCCTGGTCCTGCCCTCTGA GCCTGAAGCCCAGAGGCTTCCAAACTTCTACCCACCCTATCCTGATATTCCAGCAGGATG GAGGGCAGGACAGGGACTGGGAGTGTGTGAAGGGGGCTTGGTGGTGGAGGATAGGCTACG GGTCCTGGAGGGCAGCTTGGGGCATCCAGCCCAACTAACCCCTGCATCGCCTCCTACACA TTGCCTCCTATCCCTGGACTCCAGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCC TTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTT GGAAGAGGAGACACCGGCCTGGGCCACAGGTCAGGAGCCACCTCGGGGCTGACCGCACTG TCTCCAAAGCCATCTTAGAGGGGAGAGTTGGCAGGGGTCCTGGGCTCTGATCTGAGAAGA GATAGGGTCCTGCCCCAGGGAGCCTTAGCTTGCGGGGAGACAGGACCTGCTCATGGTGGG GTAAACACCTGGCTTTAGCAAGGAGGCTTAAGGGCAGGGAGAAGAAGAGCAGGATGCTCT GTGGTTGGGGCTAGATTCCTGGAATGGAGTTTCTCTGGCTCTGCTCCTGGGCCAGTGTCT AAGCCAATCCCTCCTCCTACCCTCTGCTTAGCAGGGACAGCAGCTACTACCTTGCAGTCA GCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCA TCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACC ATACAGGTGGGCCTTTCCCACAAGGCTCACCTCTAGGAAGCCTGGGTTCCTCCTCCTGGC CCCTCTATGCCCCCTCCCATTATAGGACCCCAGTTCCCCTTTGGACAAAAGATGGCTTCC CAGGCAGTGACACTCTGTGCTTTTGGTTCAGACCAGGTCATCAGGGAGCGGAAGGCAGCC CTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGAC ATTCTCCTGGGTGCCCGGGTGAGTACATTGTTGCCCACCCCTACCTGAGGACTGGTCCCA GAGAGGTCTTCAACCATCCTCCCAGGACAGCAGAAGGAGCTCTTAAGCATTTCCCCCTTT CCTCAGCAAATATAACCTGTTCCTCGTCCCATGAAACATATTAGCAGGGGTTCAGAGGTG GGCAGGTGTAGGGTGTGTGTGCCTGAGCTGTGGAGTTGGGAGCCTAGGTCACGTGGTAGT GGCTGGACGACATTTCTAGACTTCTAAGATCCCCCAAAATGTTGGCCTTGTAGAATCCTA GAATCTTAGACTTCATTCATTCATTCATTCATTCAGTAAGTTCTTTATTCATCAATTCTA GAAACTCACTGAGTTCTGACTCTGGGTCATTTCCGTGCTAGGATGCAGAGATGGGAAAGA CCTGGCCCTTCCTTCCAGATGCTTACAGTCCAGCAGGGGAGACAGTAGGTAGATGTTGAC CAAAATGTCTTCCTCTGGCAGGTGGTATTCTATGTGCCCAGTGAGCAGAACAGTCAGGGC TGGACAAGGTCACAAGTCATTTGGCCAGAGCATTTAGGGAGGGCTTTGTGGAGGAGGAGG CATCCAGGCTGAGCTTTGAAGGAATATAGGAATCTGGGGGAAGGTCCTAATCCACCCTCT GAAAAGGAGCTTTCACTCCCTCCCAGAGACCTTCATTTGACAACCACCATTATGAGTTCT TCTTGTTACCCACCTCCAATACCTCAAGCTGTCCTATTATGCCTTCCCTAACCCAGGATG AAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTG AAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACC CTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCT TCCAGTGGTGAGTCTGAGGGTGGGCCCGGTTTATCCTGCTCAGCCCTTGGGAAGGGCGAT GCCCATCCTGTCCTGAACCATCCTGGAAATCAGGTGAGGTGGCGGCTGCTATCCTGTTAC CCCCAGTGTCATACCTTTTGTGGTGGTGGGGGGTGGGGAGAGTGGTTGGCTGGGCACAGA TGCACCCCTGAGCCCATTCTCCCAAAATGGAGCCTTTCAGAAGTGTTATGTAGAGAAAGT TGTCAACAAGAGGCTGATATTTTGTGTGCTAACTTCTTCTGACGGTAGAACCTGATTACC CTTCTGGGTCCCTGGATAGAGTAGGGAGAGCTGGGAGAGAAAGAGGTGGAAATGTGGGGG TGAACAGAGCTGAGACAGCTGGGAGAGCCAGTTCCTTGCTACTTGCCTTTGGATGGCAAT ACTCAGCTTCCAGATGCCATATCTCTCCTGCTGGTGAAGGAGAAAAGACTTCCCCAAACT TCATCACTTAAAAACTTTCCATTGTTTTCCCCTGTTTCTTGGCTCAAGACTGAACTCCTA AACACTTAAGGATTGACCCTGACCTCTCTGCAGTGTGATCTCTGGGAGTCTCTCAAGAGG CTCCTTCACCCTTGCTGGCTGCCTGTTCCCCTCAGGCCTTTGCTTGTGGTCAGACAACCT GCCTTTCTCTCTGGGCTCCTGAGCAGCCTCCAAGAGGGGGCTAGGCACACAGCAGGGGTA CAGAAAATGCTGAGCCAGAGGGGGAACTTTAGATCCACTTGAAAGGGACTGACCTATAAC TCCAGGGTCTAGGACCTGGAGTATGAAGCCTCCATTACCATTTCTGTTGGTCATATGTGA GAATCCCCCCCCCACGGGGTATCCAGACACATGCCAGGTGCTATCAGGGGTGCAGAACGG AAGAGAAAGAGAAGCCATGCTGCTCGTGGGGAGTTTTATGGAGACAAATTCACATAATCA AACAGCGAGAGAAAAATCACAGGATCACGTGGTCTGAATGTTGAGGGCAGAGGGAAGGAG TGAGGCTTGAACTGACTTTCTAAGGAGGGTTAAAATTCAGGCAAAGAGAGAGAGGTAGGC ATTGTAGGCTGGGTAACAATGTGAACACAACCCGAGGCAGGGATTAGAATATTTATTTTA TTTTCACGTCATTCCATCTAGAGCTTGAAGCAACTTAGAGGACAGTTATTCAATAAAATA GTAAAATGCAAATGAAAAATAAGAGCCAGTGGGGAGTTTGGGGACTCTGCAATAAAATAT TGCCCTGTAGTTATAGTTGGATGTCACATTTGGGCCTGAGCTTCCCGGTTGCCAAAGGGA AAAGACACACACACACACACACACACACTTCACCTCATTAAATAATGCATCAACTTTGGT TGGTTCATTCAACCAACGTGTATCAGCCCCAGTTTCTTTCATTCAGCTCAGTAGGGGAAA CCAAGCTGAAACCTAAAGAACTGTCCTTTGTAGGCTTCCATGGGGGTCCTGAGAGTTGCA GAAGTGACCTTGTCTTTGATGGCTGGGTGCACCTTCATCTCTAGGGTCCTGTGCCTTCTT CTCCTACCAGTGAAGATGAGAAAGGGATGGAGAAAAGTGGAACCAGATCCTTTAGATCTG AGTGTTCACACCATGTCAGGCCTAGCCTGGCCAGGGGCACTTGGAACTCTGTGCCTCTGA CTCTTGAGTGTGTGGTGGTGGTGAGGGAGGAAAACTGGGGCTGGGGTCTGCTTTCTCGCC AAATCCTGTTGCTTCCCATTCCAAGAATGTTCTGGTTGTGTTGCTGGCAGGGATGATCTG GGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTG CCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCT GCAGGTGGGATGGGTGGATTTGGGGGTGGAAAAGGAGTCCCTGCATGCTCCTCTGGCACC CTCTGTGCCTTTAGTCAAATCTTTGCACTTTTGGGGAAGAGCTCAGGCTTTGCGTTCAGA GAGCCCTGGGTCTAAATCCCAGCCCCACAACATATTGATCAATTCTTCTACCTCTGAGCC TCCATTTCCCCTTCTGTAAAATGGGGATGAGAAGAGTATCTATGTTTCTAGGCTGCTGTC AGGATTAAAGAGAATGTTCACCAAGGCTGCCATGTACCACCATGCAGGTCATGCCCTGAA CAGCACCAGGGAGCAACACTCACATAGACTATGATGCTGTGCAGTGTGCAACCTGCACAA CTGTATGTGGTAGCTTCATAAAGAGTGTTAAGCCTGTACCTGGTTCATAGCAAGCACCTG GTGAATGATAGCTGTTACTGTTGGCAGTATAATATTATGAATAATAACTTCCCAAGAGTC AGTTAGCTGAAAAGGTTTAATAGTTCCTTCCTGTTCTACCTCATGATGGATGGGTTCATT CTCCCCTTTATTCATCTCACAAATGTCTATCAGGTGCTGTACCCAGTGCCGGGATTACAG GAACTGGGCATCATGATGATCAAAGTACTGTGATGAGTCGGATGTGGTCATGAACGCTCT GTCACTGGCAGTGGTCAGGCAGGAGCTGGCACCCCAGTTAAGGGGTCACTAGGGGACTCT GACCTTATGTGGAGGTAGGCCTGGCTACCCAGGACTACCTGGTCACCAACCTCTGTTCTG CCCACAGGAAGCCTGATCTCTATGCATATCTATGCCCTCCATAGGAACAGTGCTGTATGG CCCGACCCTGAGGTACCCTTTCCCTGGGCTGGGAGATCAGACAGGGTGGGGGACTGGGAG GGTCACCCTCTGCCAGAACCTGGCGAGTGTTTAAGCAAGGCCTGTCCCTTCAGGTCTTTG ACTCTCTGCGCTTTTCCACTGAGAATGCATCCAAACGCCATCCCTTTGCCTTTATGCCCT TCTCTGCTGGGCCCAGGTATGGAGAGACCCAGTATCCCAGGCCCTCAGGACTGGGGAGGA GAGGGTGGATGACATCATAGGGGAGGCACTATTAGAAGGTACTCTGAATAAAGGGGAATC ATGCTGGGTTTGTGGTGGTTCTAATGCAGGAGGCTTCTTCTTGCAATTATCATATTCCTG TCCCTGGGAAGTGGGTGGGATAGATGAGTCATTCCAAGAGAGAACCCCATGCCAGACCCC CACCATGTGAATCTACCTGGTCTGGGACCCTCACCATGCTCCCAAGGTTTGTTTCATAAG CCCAGGTCAACCAATCTATCAGCCAGTTATTCATCCAAAAACAGTTATTGACTTTTGTTG GCTGCTAAGAGCACTGAATGTCATCACTCTGGATGCTCCATTGCACGATGACTCTTTGTG CTGCTTGCTACAGGAACTGCATTGGGCAGCAGTTTGCCATGAGTGAGATGAAGGTGGTCA CAGCCATGTGCTTGCTCCGCTTTGAGTTCTCTCTGGACCCCTCACGGCTGCCCATCAAGA TGCCCCAGCTTGTCCTGCGCTCCAAGAATGGCTTTCACCTCCACCTGAAGCCACTGGGCC CTGGGTCTGGGAAGTAGCTCTGATGAGAATGGGGTCCCAGATGGCTCAGGCTGTGACCTC CCTGGGCACCACCCTCCCCAGGCTGGGTGTGGAGGAGTTGGGGCCCCCTGCCTTCAGGAG GCTTGTAGTTTAGAAGGGAAGTAGGCATTACCATAGACGACTCCTAGAGGACAGTGCTAT GTAAAAATGTGTGTCTATAAATGTTTATCATGCATGTATTCTAGAGCTCATTCATTTATT CAACAAACATTTGGTGAGCACCTATTTCGTTCGAGAAACTTCATTTATCTCCTATAATTG GCAAACTTAAAAATGCAGCAGAAACTTACATTCCAACCTTAGAGACTCATAGTGAGCACA AGGAAAGTTTTGCCCTGAGATTCATGGTTATGGCTGGGTACCACCAAATAGAAGAATGGC TTAGGGGAGTGCCCCTTCACTGAGATGTGTTTCTTTGTTGAACTTTGTGTGTGTGTGTTT AGAATATAACAGACATAAGAAAAAATTACCTAAATGAAGACTGTACAAAATAATAAATAA TTCTGAAGCAGA OMIM ID 124075