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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DAB2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1601
Official gene symbolDAB2
Full namedisabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
Aliases,DOC-2,DOC2,FLJ26626,
Gene summaryDAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta). [provided by RefSeq]
LocationChromosome: 5   Locus: 5p13
Gene position39425335 - 39371780  Map Viewer
Gene orientationminus
Gene size53556 bp
Gene sequence
OMIM ID601236