Entrez gene ID | | 161742 |
Official gene symbol | | SPRED1 |
Full name | | sprouty-related, EVH1 domain containing 1 |
Aliases | | ,FLJ33903,NFLS, |
Gene summary | | The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q14 |
Gene position | | 38545052 - 38649450 Map Viewer |
Gene orientation | | plus |
Gene size | | 104399 bp |
Gene sequence |
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OMIM ID | | 609291 |
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