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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SPRED1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID161742
Official gene symbolSPRED1
Full namesprouty-related, EVH1 domain containing 1
Aliases,FLJ33903,NFLS,
Gene summaryThe protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq]
LocationChromosome: 15   Locus: 15q14
Gene position38545052 - 38649450  Map Viewer
Gene orientationplus
Gene size104399 bp
Gene sequence
OMIM ID609291