Entrez gene ID | | 1647 |
Official gene symbol | | GADD45A |
Full name | | growth arrest and DNA-damage-inducible, alpha |
Aliases | | ,DDIT1,GADD45, |
Gene summary | | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p31.2-p31.1 |
Gene position | | 68150883 - 68154019 Map Viewer |
Gene orientation | | plus |
Gene size | | 3137 bp |
Gene sequence |
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OMIM ID | | 126335 |