Entrez gene ID | | 1650 |
Official gene symbol | | DDOST |
Full name | | dolichyl-diphosphooligosaccharide--protein glycosyltransferase |
Aliases | | ,AGER1,KIAA0115,MGC2191,OKSWcl45,OST,OST48,WBP1, |
Gene summary | | This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p36.1 |
Gene position | | 20988037 - 20978260 Map Viewer |
Gene orientation | | minus |
Gene size | | 9778 bp |
Gene sequence |
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OMIM ID | | 602202 |