Entrez gene ID | | 171546 |
Official gene symbol | | SPTSSA |
Full name | | chromosome 14 open reading frame 147 |
Aliases | | ,C14orf147,SSSPTA, |
Gene summary | | Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM] |
Location | | Chromosome: 14 Locus: 14q13.1 |
Gene position | | 34931468 - 34902144 Map Viewer |
Gene orientation | | minus |
Gene size | | 29325 bp |
Gene sequence |
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OMIM ID | | 613540 |
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