Entrez gene ID | | 1759 |
Official gene symbol | | DNM1 |
Full name | | dynamin 1 |
Aliases | | ,DNM, |
Gene summary | | This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q34 |
Gene position | | 130965663 - 131017527 Map Viewer |
Gene orientation | | plus |
Gene size | | 51865 bp |
Gene sequence |
| |
OMIM ID | | 602377 |
|