Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DSPP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1834
Official gene symbolDSPP
Full namedentin sialophosphoprotein
Aliases,DFNA39,DGI1,DMP3,DPP,DSP,DTDP2,
Gene summaryThis gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q21.3
Gene position88529681 - 88538025  Map Viewer
Gene orientationplus
Gene size8345 bp
Gene sequence
OMIM ID125485