Entrez gene ID | | 197258 |
Official gene symbol | | FUK |
Full name | | fucokinase |
Aliases | | ,1110046B12Rik,FLJ39408, |
Gene summary | | The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q22.1 |
Gene position | | 70488498 - 70514177 Map Viewer |
Gene orientation | | plus |
Gene size | | 25680 bp |
Gene sequence |
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OMIM ID | | 608675 |
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