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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NLRP7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID199713
Official gene symbolNLRP7
Full nameNLR family, pyrin domain containing 7
Aliases,CLR19.4,FLJ94610,HYDM,MGC126470,MGC126471,NALP7,NOD12,PAN7,PYPAF3,
Gene summaryThis gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.42
Gene position55458873 - 55434877  Map Viewer
Gene orientationminus
Gene size23997 bp
Gene sequence
OMIM ID609661