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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TIGIT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID201633
Official gene symbolTIGIT
Full nameT cell immunoreceptor with Ig and ITIM domains
Aliases,DKFZp667A205,FLJ39873,VSIG9,VSTM3,WUCAM,
Gene summaryThis gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
LocationChromosome: 3   Locus: 3q13.31
Gene position114012833 - 114029135  Map Viewer
Gene orientationplus
Gene size16303 bp
Gene sequence
OMIM ID612859