Entrez gene ID | | 201633 |
Official gene symbol | | TIGIT |
Full name | | T cell immunoreceptor with Ig and ITIM domains |
Aliases | | ,DKFZp667A205,FLJ39873,VSIG9,VSTM3,WUCAM, |
Gene summary | | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. |
Location | | Chromosome: 3 Locus: 3q13.31 |
Gene position | | 114012833 - 114029135 Map Viewer |
Gene orientation | | plus |
Gene size | | 16303 bp |
Gene sequence |
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OMIM ID | | 612859 |