Entrez gene ID | | 2042 |
Official gene symbol | | EPHA3 |
Full name | | EPH receptor A3 |
Aliases | | ,EK4,ETK,ETK1,HEK,HEK4,TYRO4, |
Gene summary | | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p11.2 |
Gene position | | 89156674 - 89531284 Map Viewer |
Gene orientation | | plus |
Gene size | | 374611 bp |
Gene sequence |
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OMIM ID | | 179611 |
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