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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EPOR (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2057 Official gene symbol EPOR Full name erythropoietin receptor Aliases ,MGC138358, Gene summary This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. Location Chromosome: 19   Locus: 19p13.3-p13.2 Gene position 11495018 - 11487881  Map Viewer Gene orientation minus Gene size 7138 bp Gene sequence >EPOR:complement(2750683..2757820):Length=7138 CTTAGAGGCGCCTGGTCGGGAAGGGCCTGGTCAGCTGCGTCCGGCGGAGGCAGCTGCTGA CCCAGCTGTGGACTGTGCCGGGGGCGGGGGACGGAGGGGCAGGAGCCCTGGGCTCCCCGT GGCGGGGGCTGTATCATGGACCACCTCGGGGCGTCCCTCTGGCCCCAGGTCGGCTCCCTT TGTCTCCTGCTCGCTGGGGCCGCCTGGGCGCCCCCGCCTAACCTCCCGGACCCCAAGTTC GAGAGCAAAGGTAAGGATGAGCTGCGTGTGGACCCCTACGCTGGAGCCTGCAGGACCATG CTGGGGCCTGAACTCCCAGCCTAGGTCCTGGGGGCCATGCCTGTTTCTGGACTTCCTGAC CGGGTCCTGGGGGCCAAGCTGGCATCTGAACCCTTAGACTGGGTCCTGGATGGGTGGGGG GCGGGGTGGGGTATGTTAGGATCCAAGACTCCTGATCGCGTCCCGGGCAAGAGCTAGAGT GGGCTTAACATTCCCGTTTTACCTTTTCAGGGAGTCTGGGACATGCTAAATCCTAAGGGG GCTGACTTGGTGCTAAGGTCCCTGGGGGGTGGGGACCAAGCCGACCCTCCCTAGGGGAGG GAGGGTAAAGCCCGGGTCCGAGTTAGAGGGGCCAAGCCACAGGCTACTGTAAACACGGTT TGTGTGAGGGCGCCAGATCACTTGCCCGGCCCGGTGGAGGGAGGGAGGCGGGGGGCACGG TTGGCGCTATCGGTTGGCGGGGAGCCTGCCGGGGCCGATAGGGGGCCCGCCTCTCCGCAC ACACCCCCAGCCGCGCGCGTGTCCTAGGCTGGGGCGGGGCTGGCAGTCCCGAGCTCGAGG TCTTGAACGCCGCGCCCAGCTCAGCTGGCCGCTGGGTGGGCAGGTGTGCGCCAGTGGTGA CGGCGGGGGACAGTAAGGCGAGAAACTTGCCCCTGGGAATTAGGGGGGCACCACCTCTGC GGACCCCTCCAAGGGACCCGCTTGGGAAGATGGCAGGGCGGGGCTTTTTTCTTATCGGGT CCGCCCAGGCTGCGGGAGGGAAGAGGAGGGGGCTGTCTCCCGAGGATAGAGCTCAGACCC CCATGCCCTTCCTTTGTCGCCCCTCCCCAGCGGCCTTGCTGGCGGCCCGGGGGCCCGAAG AGCTTCTGTGCTTCACCGAGCGGTTGGAGGACTTGGTGTGTTTCTGGGAGGAAGCGGCGA GCGCTGGGGTGGGCCCGGGCAACTACAGCTTCTCCTACCAGCTCGAGTGAGTCCGATCCG GCGGGTGCCTCCAAGGGCGGAGGGAGGGGGTGGGGCAGAGCTCCCTGGAGGTCGTAGCCT CGTATGTCCCCTGCTGTTTGAGGCCCGACGGCGCCTCCAGTCGTGGTCACTGGAGGGAAA CCTGCGGGTCCAGGGCTGGCACGCCCTCTATGGGCCGGGGCGCGAACACTCCCGCGATCA CCGCTGGAACGCGACCCCAAACATCAGGCTGGGATAACAACGCCTCCAAATCGAGGGTAA GGCGTTACTACGTCGGGGCTGGGACGCCTTCTCGAGGTAGTATCCAAAAGGAGGCCAGCA GTGGCTCATGCCTGTAATCCCAACTCTTTGGAAGGTCGAGGCGGAAGAACCGCTTGAGCC CAGGAGTTCAAGACCAGCCTGGGCAACACAGCGAGATCCCCGTCTCTTAAAAAAAAATTA GACTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGA TCACCTGAGGTCGGGAGTTTGAGACCAGCCTGGCCAACATGGAGAAACTCTATCTCTACT AAAAATACAAAATTAGCCGGGCGTGGTGGCGCATGCCTGTGATCCCAGCTACTCGGGAGG CTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGTTGCGGTGAGCCGAGGTAGCGC CATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCGTCTCAAAAAAAAAAAAAAAAAA AGCCAGGCGTGGCGCGTGCCTGTGGTCTCAACTACTTGGGAAGCTGAGGTGGGAGGATCC CTTAAGCCCCAGAATTTGAGGCTGCAGTGAGCCATGATCGCGCCACTGCACTCCAGCCTG GGCGACGAAGGAACACCTTGTCACACACACACACAAGGCTAGACCTTGTGTCACACATAC ACACTGCCCCCCACAGGCCGGGCAATGCCAACTCCCCGGTCCCCCCTCCCAACCTGCTCC CTTCCCTGGGCGCATAGGGATGAGCCATGGAAGCTGTGTCGCCTGCACCAGGCTCCCACG GCTCGTGGTGCGGTGCGCTTCTGGTGTTCGCTGCCTACAGCCGACACGTCGAGCTTCGTG CCCCTAGAGTTGCGCGTCACAGCAGCCTCCGGCGCTCCGCGATATCACCGTGTCATCCAC ATCAATGAAGTAGGTAAGTGCTCTGGGAATGGAGGAGTGGTCGGAGGAGAGGGTCTCAGT CCTCGCCCACCTGACCAACCCCCATGCCTGCAGTGCTCCTAGACGCCCCCGTGGGGCTGG TGGCGCGGTTGGCTGACGAGAGCGGCCACGTAGTGTTGCGCTGGCTCCCGCCGCCTGAGA CACCCATGACGTCTCACATCCGCTACGAGGTGGACGTCTCGGCCGGCAACGGCGCAGGGA GCGTACAGAGGGTGAGGCCAGCCCCTACGGCCCAGCCCCCAAAGCTCCACTGACTACGGC CCAGCCACGCCTCTCGAGGTCGCGCCCGGTGCCGCTTTCAGGGCCGGTCCGTAACATCCC ACATCCCATTACCCTGGTGCTGAAGACCGTTCCACGCCCACAGACACACCCCCTTTCCTA ATGTCCTCGCAAGCCTGTTGAACCCCAACTTCTTCTCCCTCCGGCCCGTAACCCTAGACC CCTTTAGCGCCCGGGTCCCTCTACGAGTGCTAGCCCAGATATTAAATTGCCCGGGTCCCG CCCTTTCGTACCAGAGACTCTCTCTCTGATTGGCCCTGAGCTTTCTTGGGCTCCTCCCCC TACTCTTATTGGTCCCATTGCAATTCTAGGGCACCGTTTTCCTTTCCCCTGATTGGCTCA GTTCCACCAGGGCCCGCCCCCACGTCATCTATTTTTGTCTGCTACGCGTCCCTCGCCCTG ATTCCGCCCCCAGGTGGAGATCCTGGAGGGCCGCACCGAGTGTGTGCTGAGCAACCTGCG GGGCCGGACGCGCTACACCTTCGCCGTCCGCGCGCGTATGGCTGAGCCGAGCTTCGGCGG CTTCTGGAGCGCCTGGTCGGAGCCTGTGTCGCTGCTGACGCCTAGCGGTGAGGCCCCAGG CGGGGGTGTAGGAGGAGCCAGGGCGAATCACGGGGCAAGCCCACCGCCCTGACCTCCTCC CCGCCTCTTAGACCTGGACCCCCTCATCCTGACGCTCTCCCTCATCCTCGTGGTCATCCT GGTGCTGCTGACCGTGCTCGCGCTGCTCTCCCACCGCCGGTGAGCTCCCCATTTGGGCGC TGGGCCCAGACTCCTCCCCGCCAACGGTCCTCTTTCACTATGGAAACCTAGGCTCAGAGA GAGACACGCACTTGCCCAAGGTCACGCAGTAAGGATTCACATCAGTGGCAGGGCTGGGAT GCATGCCAGACTAGACCCAGACTCTTCGTTAACATTTTCTGCTCTTGGGGACTTTCACCT GATTTTCCTTCTACATCAGGGGCTGCCATTTCTTGGGTCCCTTTGTTAGTTCCTTTCCCC AGTGTCATCACCTTTGTAAAATCAACTAGATGGATTTAGTGAAAGAATTTAAGACCCTGA ATGCCTCCGCACCCCTGCGGTCAAGCTTCTCAGACACTATGATCAGACTAGCCGTTCTGA GGTATTTGTAATTCCAAGCACACACTAGGTGGTTTCACACCCCCAAGCTTTTGCCCATGC TGTTCCCTCTGCCTGGAATGCCCTTCCTGCCTTGTCTGCTAAGCAATCTTCTAGTCGTCT TTCATGGCCCTGTTCATTTACTTGGTTGGAAAATACAAACAGAGTGCCAAACATGTGCCA GGCACTGGAGAGAGAATGGAGAACAAGCTAGACCCTGACCACAAGTCCCTGACCTTGTGG ATCTCAAGTCAACAAACAAGGGACCCAAGAAATATTTGATGACAAATTGTAATGAGTGAT ATCACAGAAACAAACAGAATGTGGTGACATGACAGGATGGTCAGGGAAGGCCTCCAGGAG GAGGTGACATCAGAGTGGAAACCTGAAGATTGGAAGGAAGCAGCCGCTTGAAAAGTGGGG AGAAGAAACAGCAAGTGCAAAGGCCCTGAGGTGGGAATGAGATTGGAACGTTCAGCCAGC TTCAAGAATTGCCACATGGCATGGCCTGGCATGGTGGCTCACGCCTGTAATCCCAGCACT TTGGGATGCCGAGGCAGGCAGATCACCTGAGGTTGGGAGTTCGCGACCAGCCTGACCAAC ATGGAGAAACCCCACCTCTACTAAAAATACAAAACTAGCCAAGCGTGGTGGCACATGCCT GTAATCCCCGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGTGGAGG TTGCGGGTGAGCCGAGATCGTGCCATCGCATTCCAGCCTGGGCAATAAGAGTGAAACTCC GTCTCAAAAAAAAAAAAAAAATTGCCACATGGCTAGAGTGGTATGTAAGGGGGTGTGGCA GATATTGAGATGAGGGAGGTGACAGGGGTCATATAACGCAGGGCCTTCTGCAGGGTGGTG GGGAGGAGTTTGGAATTTTTTTTTTTTTTGAGACAGAGTCACTCTTGTCGCCCAAGCTGT AGTGCAGTGCAGCAGTCTTGGCTCACTGCAATCTCTGCCTCCCAGGTTCAAGTGATTCTC CTGCCTCAACCGCCTGAGTAGCTGAGATTACAGGCGTGCATGCCCGGCTAATTTTGTAGT TTTAGTAGAGACGGGGTTCCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGG TGATCTGCTCACATCAGCCTCTCAAAGTGCTGGGATTATAGGCATGAGCCACCGTGCCTG GCTTGGATTTTATCCTAAATGCCTTCTCTCATTACCCCAGAAGGTAACATAATATTTATC TATGAAGTGACATCATGGACCTCCTGGAAAAATCTGGGCCAGGGTTTTGGGTTTTTTAAT TTATTTTATTTTATTTTTTTTAGAGATGGGGGTCTCACTATGTTTCCTAGGCTGGTCTTG AACTCCTGGGTTCAAATGATCCTCCCACCTCAGCCTCCCAAAGTACTGGGATTATAGTGC TGGTGTAAACCACTGCACCTGGCCATGGCCAGGATTAAAGGGAGAATGACCAAGGTATAT TGAACTCCTATGCACCCTTCAATACCCTGTTCCATTTACCCTTTTGTAGGGCCTTGCTGA TGCTTCAGCCAAAACCCCTGTCCCCTGGCCCTGATGTACTCCTCTGCCTCCATTGTGATC ACAGGGACCAAGTGTATCTGTGCCTCTATGACTGGGAGTGGAGGGGGAATTGGTGAGTAT TCAATGAGTCATATCTATGTAACTATTTATATTGGCTTCAACAGGGCTCTGAAGCAGAAG ATCTGGCCTGGCATCCCGAGCCCAGAGAGCGAGTTTGAAGGCCTCTTCACCACCCACAAG GGTAACTTCCAGGTAGGTGGCCTGGTTGTCCCCTCAGTGCCTGGGCTTCCCTGCTTCTTG CAGCCAAACTGCAGGCCTCTCTGAGCAGGTTGGTGCTATTTCTTCAGCTGTGGCTGTACC AGAATGATGGCTGCCTGTGGTGGAGCCCCTGCACCCCCTTCACGGAGGACCCACCTGCTT CCCTGGAAGTCCTCTCAGAGCGCTGCTGGGGGACGATGCAGGCAGTGGAGCCGGGGACAG ATGATGAGGGCCCCCTGCTGGAGCCAGTGGGCAGTGAGCATGCCCAGGATACCTATCTGG TGCTGGACAAATGGTTGCTGCCCCGGAACCCGCCCAGTGAGGACCTCCCAGGGCCTGGTG GCAGTGTGGACATAGTGGCCATGGATGAAGGCTCAGAAGCATCCTCCTGCTCATCTGCTT TGGCCTCGAAGCCCAGCCCAGAGGGAGCCTCTGCTGCCAGCTTTGAGTACACTATCCTGG ACCCCAGCTCCCAGCTCTTGCGTCCATGGACACTGTGCCCTGAGCTGCCCCCTACCCCAC CCCACCTAAAGTACCTGTACCTTGTGGTATCTGACTCTGGCATCTCAACTGACTACAGCT CAGGGGACTCCCAGGGAGCCCAAGGGGGCTTATCCGATGGCCCCTACTCCAACCCTTATG AGAACAGCCTTATCCCAGCCGCTGAGCCTCTGCCCCCCAGCTATGTGGCTTGCTCTTAGG ACACCAGGCTGCAGATGATCAGGGATCCAATATGACTCAGAGAACCAGTGCAGACTCAAG ACTTATGGAACAGGGATGGCGAGGCCTCTCTCAGGAGCAGGGGCATTGCTGATTTTGTCT GCCCAATCCATCCTGCTCAGGAAACCACAACCTTGCAGTATTTTTAAATATGTATAGTTT TTTTTTGTATCTATATATATATATACACATATGTATGTAAGTTTTTCTACCATGATTTCT ACAAACACCCTTTAAGTCCCATCTTCCCCTGGGCATAGGCCATAGGGATAGAAGTTAAAG TTCTTGAGCTTATTCAGAAGCTGGATCTGCAATCTGAATGCTACTCATAACATAACAAAA TAGTATGTTAAACAGCTCTTAAATCTTACTGGCTTACCACATTAAATGATTTCTCTCTCC TAACTCAGCTCAAATGGGCAGCCATCCATGGGATGAGTCAGAGGTTCAGACTCTTCCAGT CTGTAGCTCTACCTTCTCTTAGGGTACTTAGATGGATCCCCTGTTCTACAAACTGCCAGT CAGCAAGGGAAGAAAAAGGGCAGCAATGACCCTCAATGGGCCATTTGAGGGATCTGGCCT GGAAATGGGCTTCCTCTCTTCTTCTCACACCTCACTGGCTGGAAACAGTCACATGACCCC AGTCACATGAAAGGCCAGGAAACTTAGTTTAGCTGTACACCCAGGAAGGGCAAAGCTGTT TAAGGGCCACTAGCTAGTCTCTGCCACTAATAATAATAAAAGTAATTCTGAATCAGGC OMIM ID 133171