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Gene information for ESR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2099
Official gene symbolESR1
Full nameestrogen receptor 1
Aliases,DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1,
Gene summaryThis gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q25.1
Gene position152011631 - 152424409  Map Viewer
Gene orientationplus
Gene size412779 bp
Gene sequence
OMIM ID133430