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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for F2RL2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2151
Official gene symbolF2RL2
Full namecoagulation factor II (thrombin) receptor-like 2
Aliases,PAR3,
Gene summaryCoagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q13
Gene position75919240 - 75911307  Map Viewer
Gene orientationminus
Gene size7934 bp
Gene sequence
OMIM ID601919