Entrez gene ID | | 2151 |
Official gene symbol | | F2RL2 |
Full name | | coagulation factor II (thrombin) receptor-like 2 |
Aliases | | ,PAR3, |
Gene summary | | Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q13 |
Gene position | | 75919240 - 75911307 Map Viewer |
Gene orientation | | minus |
Gene size | | 7934 bp |
Gene sequence |
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OMIM ID | | 601919 |