Entrez gene ID | | 2191 |
Official gene symbol | | FAP |
Full name | | fibroblast activation protein, alpha |
Aliases | | ,DKFZp686G13158,DPPIV,FAPA, |
Gene summary | | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q23 |
Gene position | | 163100045 - 163027200 Map Viewer |
Gene orientation | | minus |
Gene size | | 72846 bp |
Gene sequence |
| |
OMIM ID | | 600403 |