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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FAT1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2195
Official gene symbolFAT1
Full nameFAT tumor suppressor homolog 1 (Drosophila)
Aliases,CDHF7,CDHR8,FAT,ME5,hFat1,
Gene summaryThis gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q35
Gene position187644987 - 187508937  Map Viewer
Gene orientationminus
Gene size136051 bp
Gene sequence
OMIM ID600976