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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ABCB7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID22
Official gene symbolABCB7
Full nameATP-binding cassette, sub-family B (MDR/TAP), member 7
Aliases,ABC7,ASAT,Atm1p,EST140535,
Gene summaryThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq]
LocationChromosome: X   Locus: Xq12-q13
Gene position74376132 - 74273105  Map Viewer
Gene orientationminus
Gene size103028 bp
Gene sequence
OMIM ID300135