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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MS4A2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2206 Official gene symbol MS4A2 Full name membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) Aliases ,APY,ATOPY,FCER1B,FCERI,IGEL,IGER,IGHER,MS4A1, Gene summary The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Location Chromosome: 11   Locus: 11q13 Gene position 59856137 - 59865940  Map Viewer Gene orientation plus Gene size 9804 bp Gene sequence >MS4A2:5161932..5171735:Length=9804 AACCCATTTCAACTGCCTATTCAGAGCATGCAGTAAGAGGAAATCCACCAAGTCTCAATA TAATAATATTCTTTATTCCTGGACAGCTCGGTTAATGAAAAAATGGACACAGAAAGTAAT AGGAGAGCAAATCTTGCTCTCCCACAGGAGCCTTCCAGGTAGGTACAAGGTATTATTTTT TTCTACCCTCAGTCACTTAGTGGCAGGGGAAGTCATAGTCACGGTGCTTAGGAGATGAAA CTTTATTGATTTAGGCATGGATCCATCTAGTTTAATTAATATATTGGGTATGAGGAAGCT ACTTGCTGTACTTTCCATGTGGTTCTCTCTCCCTGGAGAGGAACATTTTTACTCAGCTTG CAAACTGGAAATAGATTTTCTCACATTAGAAGCTCATTTTCTGGGTATGAGACAGGAGAG TTCATACTGTGTATGTAGATCTCTGGCTTCTGGGTCTGACATGTGCTGAGGGACACATAT CCTTCACACATGCTTTTATAAATACTTGATAAAGTAACCTGCTTCTTGATTGGTCTTTAT AATCCATAAGCTGTGGGATGCTTCTCTGAAGATGAAAATAGTAATAGAGTCCCATCTAGC TATTCAAAGCCATTCCTTCATTGTATTCTGTGCACATGAAGTTGGGGTTTGTTACTGACA AAATATATTCAGATACATTTCTATGTTAAAAGGATTGTGAGATGCATAGGTAAATGTGTT TATTTTCAGTTTTACTTGTCAACATAGATGAATGAGAAAGAACTTGAAAGTAACACTGGA TTAAGAATAGGAAAATTTGGCATGGATTTTGCTCCATTTTGTCCCATCTAATCACTTGGA TAGTGTTCAGGTGTTCTTGGTCAGTTACTTGGATGCTCTGAGCTTTAGTTTCTTGGTGAT TACAATGAAGATTTGAATTACAGGATGGCTTTGAAAAAATAAACAAAACTCCCCTTTCTG TCTGTCGAGAATGTTGCACAGGGAGTTACAGAATGTTCTCATGACTGAATTGCTTTTAAA TTTCACAGTGTGCCTGCATTTGAAGTCTTGGAAATATCTCCCCAGGAAGTATCTTCAGGC AGACTATTGAAGTCGGCCTCATCCCCACCACTGCATACATGGCTGACAGTTTTGAAAAAA GAGCAGGAGTTCCTGGGGGTGAGTGAGCCTCCTCCAACTTTGACTAGAGTAAGGGTTGGG TCTAGAAAAGAATATTGAGTTGCATCAACTGTTTTCCCACTTGGATTCATGAGAGGTGTT AGGTCCTTTAAAAAACATGGTAGATAAAGAGTTGACACTAACTGGGTCCTTTTGGGAAGA GAGAAGCATTTCCTCATAAAGACTTTAAATTGCTAGGACGAGAATGGCCAACAGGAGTGA AGGATTCATAATCTTTATCTTTACTTAGATGTAAAGAACAATTACTGATGTTCAACATGA CTACGTACATAAAGGCGCATGGAGAAAAGTATTGGCCTTCCATGCATTAGGTAGTGCTTG TATCAATTCTTATAGTGGCTAGGGTATCCTGGAAAATCTTACGTGTGGATCATTTCTCAG GACAGTCTAGGACACTAACGCAGTTTCTCATGTTTGGCTTCTATTATTAAAAAATGATAC AATCTCGGGAAAATTTTTTTGATTTTCATGAAATTCATGTGTTTTTCTATAGGTAACACA AATTCTGACTGCTATGATATGCCTTTGTTTTGGAACAGTTGTCTGCTCTGTACTTGATAT TTCACACATTGAGGGAGACATTTTTTCATCATTTAAAGCAGGTTATCCATTCTGGGGAGC CATATTTGTGAGTATATATCTATAATTGTTTCTGAAATAACACTGAACATAGGTTTTTCT CTTTCTCAGATCTAACCAGTTGTTTATTCCCAGTATTAACATGATATTTATAATTCTTAA TTATAAATTATATGTGAGCATATATAACATAGATATGCTCATTAACAACAACAAAAGATT CTTTTTACAATTAACGGTGGGTTAAACATTTAGCCCACAGTTTTATCCCATGAGAAACCT GAATCTAATACAAGTTAAATGACTTGCCTAAGGGCCACTTGACTAATAGTAATTGAACCT AAACTTTCAGAATCCAACTCCAGGAACATACTTCTAGCACTATTCATCAATAAAGTTATA TGATAAATACATACAACTTTATCTGTCAACTAAAAATAACAACAAAGGCTGGGCATGGTG GCTCACACCCGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAG GAGTTTGAGACCAGCCTGACCAACATGGTGAAACCTCATCTCTACTAAATATAAAAAATT AGCTGAGTGTGATAGTGCATGCCTGTAATCCCAGCTACTTAAGAGGCTGAGGCAGGAGGC TTGTTTGAACCTGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCATTGCACTCCAGC CTGGGCAATAAGAGCGAAACTCTGTCTCAAAATAATAATAATAATAATAGAAAATAAAGT TGTCTTCATGAAAAATGAGGAAAGAGATTGCTGGGGTGAGAAACATTAAGATCAAAGGGC ATATGGTGACCTTCTATGCCCTAGAAACTCTTTTAGGTATTTTCTCCTGGTATCTCTTTT ACTCATCGTTCTATCTGGAAAAATAGGTGGATGAGTGAGATAATAAGGTATATAACTTTT TAAAGGTCTAATTGACATATAATAAATTGCAAGTATTTCAGATGTACAATTTGCTAACCT TGACACACATAGACACACATGAAAACATCACCACATTAATACAATGTATGTATCCATCAT TTCCAAAAGCTTCCCTGTGTATCTTTGTAACTCTTTCTTCCTCCCTCCACTCCTTGTCCT CTCGTTCCCAAGAAAACATTGATCTGCTTTCTGTGAATATAAATTAACTTACATTTTTTA GAGCTTTATATAAGTATGTTCTCTTTACTGTTTGTCTTCCTTCGCTGCACAGTTATTTTG AGATTCTTCAAGTTTTTTCTTTATATCGATACTTCATTCACAAGAATATATTTTAATTCT AGACTATGTCACATTGACTTTGTAGTCTGCTAAATCCTTAGTGCTCAGATGACTTGTTCA GGACTCTCCTTGAACCTGTACCTCTGTTATAATTGAAACTTGTCTCTACTGTCTTTTTAT TTCAAACACAGCTTATGAGGTGTCTCTCAACCCATCAAACTCACAATCTGAGTCTTTAGG AGATTGCTTTGAATTTGTGCTATTGACTTATATTTATATCAAATATGTAAATGTTTGGTA AAAATATCATCATGTACATTTTCATAATTACTCTATATTCACATGATATATGTCAGACTC TGGAAATATGCATGCCACAGACACGTGTTTCTTGCCTAAAGGGGCTGATGGAAGACGCAC ATACAAATAGACGATTGCAATAGAATGAGAGTGGTGGTCTAATCGATTCATGCCCTGATG TTGCTGGACGTTGCTACTCCAAGAGTAACCCCTGCATTGTCAGGGTTAGCATCTCCTGGA AGCCTCATGTAAATGAAGAATTTCATGCTCCATCCAGGACCTAATGAATAAGAATCTGCA TTTTAGCAAGACCCTCATATGATTCATATACACTTTTTTTTTTTTTTTTTAGATGGAGTC TCACTCTTGTCGCCCAGGCTGGAGTGCAATGGCATGATCTTGGCTCACTGCAACCTCTGC CTCCCGGGTTCAAGTGATTCTCCTGTCTCAGCCTCCCTAGTAGCTGGGACTACAGGTGCA TGCCACAGTGGCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATTTTGGT CAGGCTGGTCTTGAACTCATGACCTCCGGTGATTCCCCCGCCTCGGCTTCCCAAAGTGCT GGGATTACAGACATGAGCCACCACACCCAGCCTTATTCGTATACACATTTAATTCTGAGA AGCACTCTATAGAAAATAAGAATAAGAAAATATTGGGCTCACAGGTGACATTAATAAGTA ACTTTATCGAGTACCCCAAATGTTACCTATGTTTGGAAGATGGGGTTAAAAAGGACACAT TGAAAACAAGAAACTCATTGTGGCTTTTTTTTCCTCCTTTTTGAACAGTTTTCTATTTCT GGAATGTTGTCAATTATATCTGAAAGGAGAAATGCAACATATCTGGTGAGTTGCCCGTTT CTGTCTTTGTCCATCCTTGAAAAGATAAGAAGAACAGAGTTTTAAGAGTCTTAAGGGAAA CACATCTTTGTCTCCTATATTACTTGTGAATGTGGATATATGATTTTGTTTCAATCTATT TTGTGTCCTAAGGCTTTTTGCAACAGAAGTTGGATATAATCATTAGAAACATAAATTGTA CCATTTAACATACAATGAAGTTTATGTTTACCTTGACGTTTCTTCTAAAAAAAGTGTCCT CACACCGGCATTGTCCTTGTAGGCATATTCACATGATCAAATAAATAATTAGTTTTCAAT TAAGGAGAATATTTGAGGAAAGACCGTACGTGTTCATGTGGTTCCTGAAGGCAGTCCAGT GAGAAAGTAATATATGCTCATTAAACAATGCGGACATTTTCAGGGTTTCCCTTTTTAACC AAAATTTGGAAGCAATGTGGAATTTACTGGATGCATCCAGCCCTGAAATGAAGATAGGTT TATTGAATGTGCCAGCAAGTGCAGGCCCAGGTCTGAGTGTTCTTCATTATTATCAGGTGA GAGGAAGCCTGGGAGCAAACACTGCCAGCAGCATAGCTGGGGGAACGGGAATTACCATCC TGATCATCAACCTGAAGAAGAGCTTGGCCTATATCCACATCCACAGTTGCCAGAAATTTT TTGAGACCAAGTGCTTTATGGCTTCCTTTTCCACTGTATGTATTTTTTTTTGTGTGGGAA GACTAAGATTCTGGGTCCTAATGTAAGTAAGAAGCCCTCTTCTCCTGTTCCATGAACACC ATCCTTTTCTGTAACTTCTATTACACAGTATAGTGGTTCTGTAAGTTCACACAGCCCAGG GAGATGCTGGCTGCCCACTCCCCTCAACCCAGGCAAATTCCTCGGGGTTAAAGTTATCTA CTGCAAGTGACGATCTCTGGGTTTTTCTGTGCCTGTGTTTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTATGTGTCACTTTAAAAGGACTGGTCAGATGGTAGGGAGATGAAAAC AGGAGATGCTATAAGAAAATAAACTTTTGGGGCGAATACCATGTGACTCTTTTTGTTTGT CATTTGTTGCTGTTCAATAGGAAATTGTAGTGATGATGCTGTTTCTCACCATTCTGGGAC TTGGTAGTGCTGTGTCACTCACAATCTGTGGAGCTGGGGAAGAACTCAAAGGAAACAAGG TAGATAGAAGCCCGATATAAAATCTTGAATGACAGGTTAACGAATTGGAGCTTTATTCCT TAAAAATATGGCCTGGGTTTTCTGAAACATTTCTTCCAGAAAATAGTTTCTCCAAGTTTT ATTACTTTGGTTTACAAATCTCACATTTTAAATCACATTTTATACCCATAAGTAGCACAC ATTTCATAATATATCCCTCTGAATGAGGGTTGGGATAATAGGATCTGTATAATGTTAGAA AATGCCTTAAAGTGTGTGGAGCATGAGAGATGGATGTGCAGAAGGCTTGTGAGGAAACCA CCCAGGTATCTGGCCTTGTTTTCTGCCCCAGAAGTAGCCGCCTATTCCTGTTTCTGTTTT ATTCCTTTGTTTCTTGACTTTTCCTTTCCAACTTGCTCTAAAACCTCAGTTTTCTTTCCT TTCTGATTCATGACTACCAAATGTTTCCACTTGCCTCACCCGTCCATTACACCTTTGATA AGAACCACCAGCACCTTGTGCTCATGTACTTGCCCATGTCTGATGGAAGAAACATACTCT CTCCATCTGTCCACTTTCCTGAGGCATTCAAGTCTAGCCACCTTTTAAAATCACTCTCCT CCAGGCTGGGCACGGTGGCTCACGCCTGTAATCTCAGCACTTTGTGAGGCTGAGGAGGGC GGATCACTTGAAGTCAGGAGTTCAAAACCAGCCTGGCCAAATGGCAAAACCAAATCTTCA ATTAAAACCAAATCTTAAACCAAATCTCTACTAAAAAATACAACAAAACAAAACAACAAC AACAAAAACAGAAAAGGAAACATTAGCCCAGCGTGGTGGCAGGTACCTGAGGTTCCAGAT ACTTGGGAGGCTGAAGCAGGAGAATCGCTTGAGCCCAAGAGATGGAGGTTGCAGTGAGCC GAGATCATGCCACTGCACCACAGCCAGGGTGACAGAGCCATACTTCCCAGCACATTGGGA GGCCAAAGCTGAAGAATAATTTGAGGTGAGGATTTGGAGACCAGCCTGGCCAACATGGTG AAACTCCGTCTGTACTAAAAATATAAAACTTAGTGGGGCATGGGGGCACACACCTGTAAT TTCAGCTACTTAGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAAGTTGCA GTGAGCCAAGATCGTGGCCACTGCACTCCAGCCTGGGTGACATAGTGAGATTCTGTCTCA AAAAAAATAAAAGAAATTTAAAAAATCACTCTCTTCCAAAGATAGATAAATAAGACAGCA GATATACTAAGGAATAACCTCACCAACTTGTCATTGACTGACATGATTTCTTTTGGGCCC ACTTGGCCAGCTAGTCTGGTTTGGTTTTCTGGAAATGAAAGAAATAATCAGAGTTTAATG ACAGAGAGCGTGAGACCCAGAAAGACAAAAGTAGATGAGGTAAGTCTCTTGAGCGAGACT TCTAGGGATGGGAAATTTGTGGTGATTGATATGAAATGATTTTTCCCTTATCAGGTTCCA GAGGATCGTGTTTATGAAGAATTAAACATATATTCAGCTACTTACAGTGAGTTGGAAGAC CCAGGGGAAATGTCTCCTCCCATTGATTTATAAGAATCACGTGTCCAGAACACTCTGATT CACAGCCAAGGATCCAGAAGGCCAAGGTCTTGTTAAGGGGCTACTGGAAAAATTTCTATT CTCTCCACAGCCTGCTGGTTTTACATTAGATTTATTCGCCTGATAAGAATATTTTGTTTC TGCTGCTTCTGTCCACCTTAATATTCTCCTTCTATTTGTAGATATGATAGACTCCTATTT TTCTTGTTTTATATTATGACCACACACATCTCTGCTGGAAAGTCAACATGTAGTAAGCAA GATTTAACTGTTTGATTATAACTGTGCAAATACAGAAAAAAAGAAGGCTGGCTGAAAGTT GAGTTAAACTTTGACAGTTTGATAATATTTGGTTCTTAGGGTTTTTTTTTTTTTTTAGCA TTCTTAATAGTTACAGTTGGGCATGATTTGTACCATCCACCCATACCCACACAGTCACAG TCACACACACATATGTATTACTTACACTATATATAACTTCCTATGCAAATATTTTACCAC CAGTCAATAATACATTTTTGCCAAGACATGAAGTTTTATAAAGATCTGTATAATTGCCTG AATCACCAGCACATTCACTGACATGATATTATTTGCAGATTGACAAGTAGGAAGTGGGGA ATTTTATTAAGTTACTCGTTGTCTGGGGAGGTAAATAGGTTAAAAACAGGGAAATTATAA GTGCAGAGATTAACATTTCACAAATGTTTAGTGAAACATTTGTGAAAAAAGAAGACTAAA TTAAGACCTGAGCTGAAATAAAGTGAGTGGAAATGGAAATAATGGTTATATCTAAAACAT GTAGAAAAAGAGTAACTGGTAGATTTTGTTAACAAATTAAAGAATAAAGTTAGACAAGCA ACTGGTTGACTAATACATTAAGCGTTTGAGTCTAAGATGAAAGGAGAACACTGGTTATGT TGATAGAATGATAAAAAGGGTCGGGCGCGGAGGCTCACGCCTGTAATCCCAGCCCTTTGG GAGGCCGAGGTGGGCAGATCACGAAGTCAGTAGTTTGAGACCAGCCTGGCCAACATAGTG AAACCCCGTCTCTACTAAAAATACAAAAAAAAAATTAGCTGGGTGTGGTGGCAGTCACCT GTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTCAACCTGGGAGGCGGAGG TTGCAGTGAGCCGAGATCGCACCAGTGCACTCCAGCCTTGGTGACAATGGGAGACTCCAT CTCAAAAAAAAAAAAAAAAAAAAAAAAGATAAAAAGTCAGAAATCTGAAAAGTGGAGGAA GAGTACAAATAGACCTAAATTAAGCTCATTTTTAGGCTTTGATTTTGGGGAGACAAAGGG AAATGCAGCCATAGAGGGCCTGATGACATCCAATACAGAGTTCTGGTAAAGATAAAATTT GATACAGGTTTGGTGTCATTATAAGAGAAATCATTATTAAATGAAGCAAGTTAACACTCT AAGAGAATTATTTTGAGATAGAAGTGAAGCTAAGCTAAACTTCACATGCCTATAATTGGA GGGAAAAACTAAGGATAAAATCTAGCCTAGAAGATACAATAATTAGTCATAAACATGCAT TGTGAAACTGTAGAGAGCAGGTAGCCCAAAATAGAGAAAGATTAGATAAAGAGAAAATAA GTATCCATCAGAGACAGTATCTCTAGGCTTGGGCAAGAGAAAAGTCCACAGTGATAAGCA ACTCCACCTAAGGCATGAATATGCGGCAGAGAAAACAGCAATAGTGAATGAATGCAAAAG GTGCTGAGAAATTCCACACATGAGTATTGTGATGAGTAAATGAATAAAACATTTGCAAAG ACCTTTAGAGAAAGAGAATGGGAGCATATGTGAGAAATAAGATAGTTGATTATGAATAGA AGGTAGTGAAGAAAAGCAAGCTAAGAAAAAATTCTGTTTATAAAAGAAGGAAAAGATAGT TTATGTTTTTAGCCTAAGTATAAGAGTCCTACAGATGGACTGAAAAAAATCAGTCTGAGA GTATTAGTCACAATTAATGAAATAATTACATTTTATGTATTGAGGATGCCAAGATTAAAA GGTGACAGGTAGATGTTAATTTCCCTAGATTGTGAAAGTGATCACGACAATCACACAACA AATAATTAAGTGACTTGGTATGCTTTATTTAATTGTAGGGCCTGAGGTTTTCCATTCTCA TTTTTCTAAAATACAATTTTGTTTCTCCAAATTTGACAGCAGAATAAAAACCCTACCCTT TCACTGTGTATCATGCTAAGCTGCATCTCTACTCTTGATCATCTGTAGGTATTAATCACA TCACTTCCATGGCATGGATGTTCACATACAGACTCTTAACCCTGGTTTACCAGGACCTCT AGGAGTGGATCCAATCTATATCTTTACAGTTGTATAGTATATGATATCTCTTTTATTTCA CTCAATTTATATTTTCATCATTGACTACATATTTCTTATACACAACACACAATTTATGAA TTTTTTCTCAAGATCATTCTGAGAGTTGCCCCACCCTACCTGCCTTTTATAGTATGCCCA CCTCAGGCAGACACAGAGCACAATGCTGGGGTTCTCTTCACACTATCACTGCCCCAAATT GTCTTTCTAAATTTCAACTTCAATGTCATCTTCTCCATGAAGACCACTGAATGAACACCT TTTCATCCAGCCTTAATTTCTTGCTCCATAACTACTCTATCCCACGATGCAGTATTGTAT CATTAATTATTAGTGTGCTTGTGACCTCCTTATGTATTCTCAATTACCTGTATTTGTGCA ATAAATTGGAATAATGTAACTTGA OMIM ID 147138