Entrez gene ID | | 2267 |
Official gene symbol | | FGL1 |
Full name | | fibrinogen-like 1 |
Aliases | | ,HFREP1,HP-041,LFIRE1,MGC12455, |
Gene summary | | Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p22 |
Gene position | | 17753047 - 17721900 Map Viewer |
Gene orientation | | minus |
Gene size | | 31148 bp |
Gene sequence |
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OMIM ID | | 605776 |
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