Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARSG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID22901
Official gene symbolARSG
Full namearylsulfatase G
Aliases,KIAA1001,
Gene summarySulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q24.2
Gene position66255323 - 66417000  Map Viewer
Gene orientationplus
Gene size161678 bp
Gene sequence
OMIM ID610008