Entrez gene ID | | 22937 |
Official gene symbol | | SCAP |
Full name | | SREBF chaperone |
Aliases | | ,KIAA0199, |
Gene summary | | This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21.31 |
Gene position | | 47517445 - 47455184 Map Viewer |
Gene orientation | | minus |
Gene size | | 62262 bp |
Gene sequence |
| |
OMIM ID | | 601510 |
|