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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DKK1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 22943 Official gene symbol DKK1 Full name dickkopf homolog 1 (Xenopus laevis) Aliases ,DKK-1,SK, Gene summary This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq] Location Chromosome: 10   Locus: 10q11.2 Gene position 54074041 - 54077417  Map Viewer Gene orientation plus Gene size 3377 bp Gene sequence >DKK1:4878505..4881881:Length=3377 GCAGAGCTCTGTGCTCCCTGCAGTCAGGACTCTGGGACCGCAGGGGGCTCCCGGACCCTG ACTCTGCAGCCGAACCGGCACGGTTTCGTGGGGACCCAGGCTTGCAAAGTGACGGTCATT TTCTCTTTCTTTCTCCCTCTTGAGTCCTTCTGAGATGATGGCTCTGGGCGCAGCGGGAGC TACCCGGGTCTTTGTCGCGATGGTAGCGGCGGCTCTCGGCGGCCACCCTCTGCTGGGAGT GAGCGCCACCTTGAACTCGGTTCTCAATTCCAACGCTATCAAGAACCTGCCCCCACCGCT GGGCGGCGCTGCGGGGCACCCAGGCTCTGCAGTCAGCGCCGCGCCGGGAATCCTGTACCC GGGCGGGAATAAGTACCAGACCATTGACAACTACCAGGTGAGAGGGGTCGGGCACTCAGA GGATGCTCTGACCTTGAAAGGGTCCTATCTGGAGACGAGGGAGTAGAACGTGCTGAATGT GTGCGGTTCAGGGAGCATTTGGTAACCCTGCATTTGGGAGCAGTGGGCAGTAACAGGTTT TGGAGAGGTGGACAGATAAGGACTGTGATCAGCGCCCGGGTCCAAGAGGGCGGGTACCTG GACGTCTGGGTGCCTCACCCTCTCCCCGAACCCTTCCCACAGCCGTACCCGTGCGCAGAG GACGAGGAGTGCGGCACTGATGAGTACTGCGCTAGTCCCACCCGCGGAGGGGACGCAGGC GTGCAAATCTGTCTCGCCTGCAGGAAGCGCCGAAAACGCTGCATGCGTCACGCTATGTGC TGCCCCGGGAATTACTGCAAAAATGGTGAGTCCTGAAAGCTCCCTTTCACACTAAAACTG TCCAGCCTTTGAGCGTCTATGAATTGGGCGGGGGCGGGGGGTTGGGGGGGGTGGGGGGAG AAATCTCCGCCCTGAGAACACTGCGGCGCCACCTGCAAATGGGTGTTCAGCATGCAGGAT TCCGCTGAAGTATCTTCATTGCAAGTGTTTAATCGGGAAGAAGAGAGAAGTTGGGAGGTC TCTGAGGTCCTTATCTTCCTCCGTGTCCCTCAATGATTCAATACAACGGTTCACCTCGTA GTGGACTCTTCCATAAAAATTTGTCTGGGGAGAACCTTGAGGTCAATTGAGAAGGGGGAT GATGAGGAGGACGATGGGATCATACAGATATCAAAGAAACCAGCTTTGGCGTTCAGCTGT CCTTTTCATTTTTCTTATTGTGATTCTCACAGTTTTGCCAGACTGGCCTCGCCTTCTGAT TTTTGCTGAAACTGTTGTCAGCCAGAGGACTGATTTATCTGCATTGGCCATTTTTAAGAG AGATCTTGGTACCCTCACAACTTGACTTCTCCATCCTTCCCCCTCCCTCTACCCTCTGCT GCCTTAATATAAGTACTCCTCCCCCCAACCACAGATCCACTAACTTTTAATTTTTCAAAA GGTGGATTTAGACAGCTAAAGAGGTCTCCAGAAATAAGCTAACAGGGCGACGACCCTCCT TAGGACCCAGCAGTACTCCAGGATGAACTAAGTAAATCTCTGTAATATAGAAATTACACA GTAAAGTAACTGGCCGGTGAGATTGCAATGTTCCAGGCAGCTGGAATTGCATTTGCTTAA CTTAGTCTGGTAGGACCCATATAGCACCAGGGGCAGAGAAGTTATTTTTAAGAACATTTT TAAAGTGACTGAGTTTCTTTTTCTTACCCCAAAGGTAATATTAAAATGGGCAGAAATCTC ACTTGCCCCTACCACAGTTGGTGGGAAAGTATTTTAAATGGCTATACTGGGGATATTACC TATGACTGACTGTATACAGTATACACATTGGTGCTTCTGTCCATCTGGAGAGTTTTGCAT TAACAGTAAAGAGGAAGTTTGGCTTGTGTTTAAAATGATGTCACTGCAATGAAGTATCTC AAGTTGATGCTGGCATAACAGACTGCCACTGTCACAGCTGTTAGCAGTAATGCATTACAA CCCTGAAGTTAATCACTATTTCCTGCTTCCTTAGGAATATGTGTGTCTTCTGATCAAAAT CATTTCCGAGGAGAAATTGAGGAAACCATCACTGAAAGCTTTGGTAATGATCATAGCACC TTGGATGGGTATTCCAGAAGAACCACCTTGTCTTCAAAAATGTATCACACCAAAGGTAAG GATGTTAAGACTCATTCTTAGCACATCAGAAGTGTCTTTTGAATTATTTTAGTGAAACGA TGCAGGTTTAACAGTAACTATGTACTTTTTTCCTACTGTCTTCTCCTTCGTAGGACAAGA AGGTTCTGTTTGTCTCCGGTCATCAGACTGTGCCTCAGGATTGTGTTGTGCTAGACACTT CTGGTCCAAGATCTGTAAACCTGTCCTGAAAGAAGGTCAAGTGTGTACCAAGCATAGGAG AAAAGGCTCTCATGGACTAGAAATATTCCAGCGTTGTTACTGTGGAGAAGGTCTGTCTTG CCGGATACAGAAAGATCACCATCAAGCCAGTAATTCTTCTAGGCTTCACACTTGTCAGAG ACACTAAACCAGCTATCCAAATGCAGTGAACTCCTTTTATATAATAGATGCTATGAAAAC CTTTTATGACCTTCATCAACTCAATCCTAAGGATATACAAGTTCTGTGGTTTCAGTTAAG CATTCCAATAACACCTTCCAAAAACCTGGAGTGTAAGAGCTTTGTTTCTTTATGGAACTC CCCTGTGATTGCAGTAAATTACTGTATTGTAAATTCTCAGTGTGGCACTTACCTGTAAAT GCAATGAAACTTTTAATTATTTTTCTAAAGGTGCTGCACTGCCTATTTTTCCTCTTGTTA TGTAAATTTTTGTACACATTGATTGTTATCTTGACTGACAAATATTCTATATTGAACTGA AGTAAATCATTTCAGCTTATAGTTCTTAAAAGCATAACCCTTTACCCCATTTAATTCTAG AGTCTAGAACGCAAGGATCTCTTGGAATGACAAATGATAGGTACCTAAAATGTAACATGA AAATACTAGCTTATTTTCTGAAATGTACTATCTTAATGCTTAAATTATATTTCCCTTTAG GCTGTGATAGTTTTTGAAATAAAATTTAACATTTAATATCATGAAATGTTATAAGTAGAC ATACATTTTGGGATTGTGATCTTAGAGGTTTGTGTGTGTGTACGTATGTGTGTGTTCTAC AAGAACGGAAGTGTGATATGTTTAAAGATGATCAGAGAAAAGACAGTGTCTAAATATAAG ACAATATTGATCAGCTCTAGAATAACTTTAAAGAAAGACGTGTTCTGCATTGATAAACTC AAATGATCATGGCAGAATGAGAGTGAATCTTACATTACTACTTTCAAAAATAGTTTCCAA TAAATTAATAATACCTA OMIM ID 605189