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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for WDFY3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23001
Official gene symbolWDFY3
Full nameWD repeat and FYVE domain containing 3
Aliases,ALFY,KIAA0993,MGC16461,ZFYVE25,
Gene summaryThis gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q21.23
Gene position85887544 - 85590690  Map Viewer
Gene orientationminus
Gene size296855 bp
Gene sequence