Entrez gene ID | | 23001 |
Official gene symbol | | WDFY3 |
Full name | | WD repeat and FYVE domain containing 3 |
Aliases | | ,ALFY,KIAA0993,MGC16461,ZFYVE25, |
Gene summary | | This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q21.23 |
Gene position | | 85887544 - 85590690 Map Viewer |
Gene orientation | | minus |
Gene size | | 296855 bp |
Gene sequence |
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