Entrez gene ID | | 23014 |
Official gene symbol | | FBXO21 |
Full name | | F-box protein 21 |
Aliases | | ,DKFZp434G058,FBX21,FLJ90233,KIAA0875,MGC26682, |
Gene summary | | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24.22 |
Gene position | | 117628300 - 117581585 Map Viewer |
Gene orientation | | minus |
Gene size | | 46716 bp |
Gene sequence |
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OMIM ID | | 609095 |
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