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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PDZD2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23037
Official gene symbolPDZD2
Full namePDZ domain containing 2
Aliases,AIPC,KIAA0300,PAPIN,PDZK3,PIN1,
Gene summaryProteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq]
LocationChromosome: 5   Locus: 5p13.3
Gene position31799031 - 32111038  Map Viewer
Gene orientationplus
Gene size312008 bp
Gene sequence
OMIM ID610697