Entrez gene ID | | 23213 |
Official gene symbol | | SULF1 |
Full name | | sulfatase 1 |
Aliases | | ,FLJ30905,FLJ38022,FLJ41750,HSULF-1,KIAA1077,SULF-1, |
Gene summary | | Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM] |
Location | | Chromosome: 8 Locus: 8q13.2-q13.3 |
Gene position | | 70378859 - 70573147 Map Viewer |
Gene orientation | | plus |
Gene size | | 194289 bp |
Gene sequence |
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OMIM ID | | 610012 |
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