Entrez gene ID | | 23236 |
Official gene symbol | | PLCB1 |
Full name | | phospholipase C, beta 1 (phosphoinositide-specific) |
Aliases | | ,FLJ45792,PI-PLC,PLC-154,PLC-I,PLC154, |
Gene summary | | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20p12 |
Gene position | | 8113296 - 8865547 Map Viewer |
Gene orientation | | plus |
Gene size | | 752252 bp |
Gene sequence |
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OMIM ID | | 607120 |
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