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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PLCB1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23236
Official gene symbolPLCB1
Full namephospholipase C, beta 1 (phosphoinositide-specific)
Aliases,FLJ45792,PI-PLC,PLC-154,PLC-I,PLC154,
Gene summaryThe protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 20   Locus: 20p12
Gene position8113296 - 8865547  Map Viewer
Gene orientationplus
Gene size752252 bp
Gene sequence
OMIM ID607120