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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NCSTN (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 23385 Official gene symbol NCSTN Full name nicastrin Aliases ,APH2,KIAA0253, Gene summary This gene encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq] Location Chromosome: 1   Locus: 1q22-q23 Gene position 160313063 - 160328742  Map Viewer Gene orientation plus Gene size 15680 bp Gene sequence >NCSTN:11801705..11817384:Length=15680 CGCCTGGAAACACGAACTTCCGGTCTCTTAGGCTCCGGGCCACAGAGACGGTGTCAGTGG TAGCCTAGAGAGGCCGCTAACAGACAGGAGCCGAACGGGGGCTTCCGCTCAGCAGAGAGG CAAGATGGCTACGGCAGGGGGTGGCTCTGGGGCTGACCCGGGAAGTCGGGGTCTCCTTCG CCTTCTGTCTTTCTGCGTCCTACTAGCAGGTGAGGCCTCCCCGCCCGTGAGCTCCGTTCT CTAAGGGGAACTCTCGGATCGGCCCCGCCGCGACCGCCACTGTCTCCCTTCTGGTTCCTG CTGCCCCTCTGTCCCCCCACCCTGTAAATCCTCTTTCTTTTTCGTTCCCACGACAGAAGT TCCCCCTTTGCCTGGACCTGAAGGTCCCTTCTCCCCCGCAGCACGTCGTGTCGCTTCACT CCCTTCTCTAGGCCTCTTCCTGGACTTCGAGCCTGACCCTCTCCCACTTTGTCCAGATGT CTCGTTTTTCCCACAACCCCAGCCACCCACCCCACAGTCGAAAGGAACAGGTGTGAAAGT TAGCTTTCTTCCTCGCGTTTAGACTTTTTGAGACGAAAGCAATCTTGTTCTGTGGGTGCT GTGCGGCGCTTAAAAGGTGGATTTCTTATTTCTTCCTCTGTTGATTACATCCTAAGTCTG TGTCCCCCTGCCTTGCCTCAGGTTTTTTTTTTTTTTTTTTTTTTAATCAGTAAAGCAAGA ATAAGGTAGGATATGGGTACTCTTAACTGTGAAGACCCTGAAGTAACAATTCAAGGAACT TTTGGCATTTATAATGTACTTAAGTGTTTGCTGATACGCGTTCATTTACTGATACATGGC TTTTTAGTTGGTCAAGCCCTAAAATGCAAATGCCTGTATATAACTATGACTGTGCCTTCC CCCAATTCACATTGTTTTTAAGGATCCTCAAAGGAGAAACTACAGCTGCCCCACACTGTG GGCACACAAATGACCTGCTGATGTTAAATTAACTGACCCGTGTATGTCATAAGGTTTCTC TCAATTCTGTTCACACTCTTGGAAAAATGCCTCAGAAAGTTTTCTTAGCCCAGCACCTGT GTATTAACCAATTAGTAATATACATACAGGATATACAAGCAGAAGTGTGATCACCTGTGC AACCAGAATCTGGCAAATCTAAGGTCAAACACCTTTCCTTTGACCAAGTTTTCTCTCTTT TAGTGTCACTGTCAATGGCGCTACATGGACTTTGTAATAACCCTTTGAGGCACATAGCTG GGTGCCATGTAGAACATGTATCTGTTACGATAAGTGTGTGCCCAAGAAATCAGAAGAATG GACTTTAATCTCATTTTAGAAAGTATGATATTAAATGATTTACCCAAGCCATACTTCAGG TTAATGACACGATAGAAGCTAGTACCTGTGTCTCTCAAATTTTTCTAACACTTTTTATCT TCCGATCAGGTTTGTGCAGGGGAAACTCAGTGGAGAGGAAGATATATATCCCCTTAAATA AAACAGCTCCCTGTGTTCGCCTGCTCAACGCCACTCATCAGATTGGCTGCCAGTGTGAGT TGAGATGGATTCATGTTTGTGGACATTGATATTTGTCTGTGCCCTAGATACTAAGTAACA TCCATGTCCTGCTTAGGAGATTTGACACTTATATTGGACTGTATGTAGGCAGTTACAGAT AACCGTCTGTCAAGCTAGGCAAGATAATTAATAAGAACTAACATTTAGTAAATGCTGCAT ACCAAGCTTTTTACATGTGCATCTCATACAACCCCAACCACAACCCCACAAAATAGGTCT TACTGTTATTGTCACTTTATAAATGATGAAACTAAAACTTAAAGAAGTTGAGTAACTTTC CCAAGATCATACTGGTAATAAGTGATGATGCCAGGATCTGGTGGCCCGAGCACTAAGCTG AGAGACCTTTTTTTTTTGACACGGAGTTTCACTCTTGTCCCCCAGGCTGGAGTGCAATGG CACGATCTCGGCTCACGGTGACCTCTGCCTTCTAGGTTCAAGTGATTCTCCTGCCTCAGC CTCTTGAGTAGCTGGGATTACATGCACCTGCCACCATGCCCAGCTAATTTTTGTATTTTT AGTAGAGATGGTGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCTTGACCTCAAGTGA TCCACCCACCTTGGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCACCCAGCC GAGCCAGCACTCTTAACCACCCTATTATACTGTTTTTTAAGGAGAAAAAAGTCTCATATT CTATGGTGTCCAGTTATCACTTGCACTCTGAACTTTTTGGAACCAAAATGGGCTAAAGGC AATGAACTATCTGAAGAGAAGGCACTGAAAATGCCAAATAGGCTGGGCGCAGTGGCACAT GCCTGTAATCCCAGCACTTCAGGAGGTCAAGGCGGGTGGATCACTTGAGGTCAGGAGTTT GAGACCAATCTGCCAGCATGGTGAAACCCCCCCATCTCTACTAAAAATACAAAAATTAGC CGGCTGGCTGCTATGGCATGCCTGTAGTCCTAGCTTCTCGGGAGGCGGAAGCAGAAGAAT CCCTTGAGCCCAGGAGGCGGAGGTTGCAGTGAGCTGAGATTGTGCCACCATACTCCAGTA TAGGTGACAGAGTGAGACACTGTCTGAAAAAAAAAAAAAAAAAAAAAAAGAAAATGCTGA ATAATTGCAAGAGGAATTAGTGAAGCATTCTATTTATCCTTTTTTAAAACTTTTTTTCCT TAAATTCAACTGACAGGCCGTTTATTTTCACACTTTGTGTGTTCCAAAAGAAGGTTCCAT GACACTGTGGCTTTAAAAACTATCAAAATCATAGGGCAGGAAAAGTAGTAATCTAAAGGC TAACCTGCTGTCTTCAGATTTTGTTTCCCATGGACAATAGCTCTGTCAGAATGTAGTTTT GCAGATAAGCAGGAAACTTGGGGTCTGATACTGGCTTCTTCATCATCAAATTGATCACCT CTGAATTTCAGTTTACCCCTGGAATAATGGTTGGAGTACTTGCATAAAGCTGAAAGTCAA ATACCTCTTAATAGTTGTTTATTGATGACGCTAGGTAAATAGGGTGGTCTCAAAAGTGCT GTATAATTTCCTGAAGCCTTCTTCCCATTTGATAAGAGAAAACTGGGACACTGAGAAGTG AAGGACTTGTTCGTGGAAGCAGTTACTACTTTTTTAGCCATCTTTCCCTGAGCTATAGTA TCTGTTAATTGTCCCATGTCCCTGCTATACAAAGCACTGGGAGTAGGTTGACTGGTTCCA AACAGCCCCAAATAAAGTTTTTGTTGTACTTAGTTTCTTTTTTTTTTTTTTGAGATGCAG TCTCGCCCTCTCGCCCAGGCTGGAGTGCAATGGCACAATCTCAGCTCACTGCAACTTCCT CCTCCCAGGTTAAAGCAATTCTCCTGTCTCAGCTTCTTGAATAGCTGGGATTACAGGCGC GTGCCACCGTGCCCAGCTAATTTTTTGTATCTTTAGTAGAGGCGGGGCTTCACCATGTTG GCCAGGCTGGTCTCGAACCCCTGACCTCGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCT GGGATTACAGGCATGAGCCACCATGCCCAGCCCTCTGGACTTAGTTTCTGAACTGGTTTG TAGGTAGAAGAGAGCTAGGTCCAGGGTGGGCTGAGATCAGACTGCTGGTCTTGCTGGAAC CTCACTATAAAGTACAGAAGGCCAGGACCCCAACCTCTTGTAACTAGGCTCTAAGAAAAC TCCTTTGGGAATAAGTCATTCTACTCTATGTTCTTAAAACAGCTCTGTAGGAAGCAAAGC CTCTAGAGGTAAAGCCACGTGCCAGTACAGAGAAACAAGAGGGGGTAAGCGGGACTGTGG CCACTTCCTCATTAAGATCTTGGTTCCTTTTCAACCTACTTATTTCCAAATCTTACTTCG TCATATCTGTCTTTTCTGAGCAGGCTCCGCCCTTTTTAATTAGTGTAGCTAACATGATAA AACTAAGGAGAAAAAAGTGATACCCAGATTTGATTTCTGATTATAATACTCTGCTTCTCT TAGACGCTTTAAAGTTCTCAAAGGGGGCTTTAAATAGGTTTCTTTTCCCTCCCTCCCTCC TTCTATCCTTTCTTCCTTCTTTCGTCTGTCCCCACAGTATGAGATGAATAGAGGTAGAAA ACCTCATTGAAGGCGCAGAGAAAATAAGCAAGTTACTTAAGACTACACCATTACTAGTTG GAACCCAGATTAGAATCCAGGTTTTTTTCAGTCCAGTATCATAGTTTGTCTTCCTGTCCT CGCTGGAGTTGAAGTTTTGGGGTGTGTGTGTGTGTGTGTCAGAGTCTCACTATGTCACCC AGGCTGGAGTGCTGTGGCACAATCTCAGCTCACTGCAGCCTCCGCCTCCCAGGTTCAAGC AATTCTCCTGCCTCAGCCTTCTGAGTAGCTAGCATTACAGGTGTGCACCATCACACTTGG CTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAA CTCCTGACCTCAAGTGATCCACCCACCCACTTCGGCCTCCCAAAGTACTGGGATTACAGG CATGAGCCACTGTGCCCGGCCGAAGTTATATATGTTTTAGTTGCCACACTATCTGTTCCT TTTCCCATGTTTTAAATGCTGTGGCAAGGGCCGGGCATGGTGGCTCACTCCTGTAACCCT AGCACTTTGGGAGGCTGAGTGGGCATTTAAAGTGATGCTGATATACAGCCAGGGCTGAGA ACTACTGGTCTAAAATAATTGATGAATAACATATCCAATTTTCTGTAGGGAGAAGACTCA CAGGGAGACCCTAGGATATCTCCACACAGATCACTGGGGACTTAAGGAGTATTACCTAAT GCCTTGAATTATGTAGAATTCAAAGTATTCTGGACTCTGGGTCATCCATCCTCTAATACA GTGCTTCCCAATCTTTATCATGTCATGAGACACATAGAAAATGTTATTTGTATAGCATCC TGGCACATAGAGAAATGGGTGATATTTTCAGGGCATCCTGGGGTAAATGATAAGTAGGCT CCTGGCTGGAGGTGACTTTGGAAACCCTAGGTTTCCTGGAATGAGGAGAACCAATGAGAG CACATCTCTGATCCATTCGAGGCTTATCAATTGGGAAGCTCTGTTTTAGAAACCTCAGAG TTCTTGACTAACCTCATCTAAAACCGGCCAGAAGCAAGTAAAGTCATTCCCAAAAAGGGC AAAAGGAATGACGATCCAGGAAAGCTCCTGAGGCCAAGGGCATGTATGCATGTGTTTTTA CAAAGGAAGATTCAAAGCTAAAACCCTGAGCTAGAGATTTAGTGGCATTTCCTAGAGAAA ATATAGGTTTGAAAACTTTGGTGTCTATTGTTGTAGAATCTTATGTATATGGCTAAATAA GGTTGAGGGCAGAGGGCAAAAAAATGAAGTTCACAGAACCTTTCTGGCATATAATGAGTC CTCTTGTGCTCTTTTATATTCCATTCCCTCCTGATAACCTTCAGATGGAGCTGGGGCAAC AGCTTTTCAGTTCAAATCTAGAGGTGCCTGTATTCACCCAAATATGTTGTGACATCTTTA GGGGATAAAAGATACGCAGAATCAGTGAGGCAAAGTCAGAATTGTTAACTATGGGAGCTT TAATTTGACTCATTCTGTCCTGGCAGCTTCAATTAGTGGAGACACAGGGGTTATCCACGT AGTAGAGAAAGAGGAGGACCTACAGTGGGTATTGACTGATGGCCCCAACCCCCCTTACAT GGTTCTGCTGGAGAGCAAGCATTTTACCAGGTAAGAACTAGATGTATCTGCTGGGAAAAC ATCCATAGAGGGAAAGTTTCAGTGAACAGTCCTCACACTTATTAGTGAAAACTTCCCTTG GCTGCCCTGGTCTGGTCAGGGGAGAGGGCAGGGTGGTCCTCAGAAGGAAAGGTGTACCAT CAAAAGAAATGATCTTGAGCTTAGGGCTAAATTTCACCTACCTGTCCCTGAGTAACCCTG GGCATCCCTCCCCTCCCTCCCTGGGGTCCTTACTCACTAAAGCTCTACTTTTTAGAGCAG ATCATTGTCCAGACTCAGAATTTAGAGACTGAAAGGGAAGAAATAAGTCAACAGTTTGAT TCCCCTAGTTCCCCATTTGTTTCCATCCTGCAGGCAGAATGTCAGGCTGTCTGATACCTT CCTGTGTTCCTTCATGGAATTCCTTTCCTATTCCAGGGATTTAATGGAGAAGCTGAAAGG GAGAACCAGCCGAATTGCTGGTCTTGCAGTGTCCTTGACCAAGCCCAGTCCTGCCTCAGG CTTCTCTCCTAGTGTACAGTGCCCAAATGATGGGTTTGGTAAGTGTCCCAAAGGATCAGG AGAGCCTACTGTCACCTAAGGCTCACTGTTGCTTCGGTCTTACGTCTTTGTGAGGGATGT ATATGTGTTTGTGTCTGTGTGTAGTGTCAGTAACTGACTCCCAAACAGGGGGTAGTGTTT ATTTGTCTTTGCTGCTCATCCCTTCCCTCTCCTGCTTCCCCTTCCTTTGCCTTACCTGGC ATTATCTCTTTTTGTCACGTGTTCACATCCCTAATCTTACAGCCTAAGACTCCCTGATAC CATTGTCTTTCTATTTTAGTGTGGATGGTAATAGACTTCATGCCTACTTCTTTGAGTCAC CACCTCCTTTTGAACTCTTAGTCCCAACTGAAAGATTCTTCTGCCGTCACCTGGTTCCTA AGTACTTGGTGTCCCAGTAACCAGTCCCCCTATTCCCCATCCTTCCCTTCAGGTGTTTAC TCCAATTCCTATGGGCCAGAGTTTGCTCACTGCAGAGAAATACAGTGGAATTCGCTGGGC AATGGTTTGGCTTATGAAGACTTTAGTTTCCCCATCTTTCTTCTTGAAGATGAAAATGAA ACCAAAGTCATCAAGCAGGTAATGACACTGCCAGCTCCTAGCAATTCCAGTTAGAAAGAA GATTATTTTTCTAGCCAGGTGTGGTGGTGTGTGCACGTAGTCCCAGCCACCCGGGAGGCT GAGACAGGAGGATCACTTGAGGCCGGGAGGCAGAGGTTTCAGTGAGCTGAGATGGCACCA TTGCACTCCAGCCTGGGTGACAGAGCAAGGCCCTGTGTCACAAAAAAAAAAAAAAAAAAA GGATTATTTTATAGGCTCTCCTATTTGGAGGGTGGCTCATTCTTCTGGTACACCTGCTGA AAGACGGTTGCTCCAAAAAGAACCAAGACGTTAGTTCTTCTCACATTCTTTCCCCACATT TTGCTCCTACCTGATATTACAGCATTAAAGCCTTTTAGACTAGAAGAAAATATAAAGAAT ATCTGAAAGAGTAATATGAAACAAGGTACACAGCCCAGGTTAAGAACCACTAGTATCGTT AAAAAAAAAAGCATTGGATTAGAGATTGAGAAATTCAATTTGGTAATTTCTGAGCTTCTT TTTAGCTCTAATATGCCTTAATTCTGGTCTAGTATTTCCATTTTGACTCATAGAGTAGTT AAGAGATTTGTCCAAAGTTGTATGGTGAGTTGATCTCCAAGCTGTGTCATATCTGATTTC CTATCTCTAGTTTGGTGCTCTTTGTATCAGACCACACTGAATCTTTTCAGTGGCTGAAGC TTCAAATTGGGCCAGGCCATCTGGAATGGGATAGTTTCATCTCCAGCTAAACCACTGAGT CTGCAACCCTTTGTAACTCTTGATGAGTTTTTTTCTTTGACCTTATAGATCCTATGGTGG TTCTAGGATAACTATAGCTCAGGGATAAATGTCTCCGAAAAGGGTGTGGCTCCATCCCAA AAGGATGGAACTGGGCCCTCCTCCTTCTGGGATGTAAGGGAGGGCCTCCACAAACTAGCT GTCTCAGTGGGGTCCATCTCCCCTTTCAGTGCTATCAAGATCACAACCTGAGTCAGAATG GCTCAGCACCAACCTTCCCACTATGTGCCATGCAGCTCTTTTCACACATGCATGCTGTCA TCAGCACTGCCACCTGCATGCGGCGCAGCTCCATCCAAAGCACCTTCAGCATCAACCCAG GTAGGGCAGATCCGAACCATGAGGGTAATGGAATAAGGGGCAGAGGGAGAGTGGAACCAG GCCAGGGAATGTTAGAGAGACTGTAATAGGGAAGGAGTAGACACCATGAAGGAGCTCTGC ATGGGAGAACTAGAAACAATTCTGAAAAATTTAGGCAGCTTGTTCCTAAAGTGGATAGTG GCAGAGAAGCCAACCTCGGACTGTTGGAAGTAGAGAAAACGACTTAGAGTCCGTGGGGCA CTGGTCAGAGATTTCCAATGTTGCCTTTATAGCTACCTTCTCCTTTAGCCTTGTTGATCT CTCATTGTTTGTGTCCTGCTTAGAAATCGTCTGTGACCCCCTGTCTGATTACAATGTGTG GAGCATGCTAAAGCCTATAAATACAACTGGGACATTAAAGCCTGACGACAGGGTTGTGGT TGCTGCCACCCGGGTGAGTGTTGGCTTCTGATCAGGATGGGCAGGGCTGGCACAAAAAGA GCTGGTAGGCCCCGCTCTAGCATATCAGATTTCAAAGTTGCTAAATTGGGAAGCCTCAAA TGGGGAGGAATCTGGGCTGTGGGACTCCTGGGTTGTCTCCATTGCCACAGGACAGGTATA TTCTCTTGACTGGAGCAAGAAAGGAGGTTTGGGGCCAGTTTTAAAGTATATATCCCCTGA CTTTTCTTCTGTTGTACCTAGCTGGATAGTCGTTCCTTTTTCTGGAATGTGGCCCCAGGG GCTGAAAGCGCAGTGGCTTCCTTTGTCACCCAGCTGGCTGCTGCTGAAGCTTTGCAAAAG GCACCTGATGTGACCACCCTGCCCCGCAATGTCATGTTTGTCTTCTTTCAAGGGGTAAGG GCTCTTTGGCTGGGGTGCAATGGCAGGGAAGAAAGAGGATAGTAAAGATGAGAGTGGCTA CTGGTTGGAGAAGACCTCAGCACTTGACCTAAGTTGTTAACCAGCACAGAGCTTCTGGAT GTGTCTACATGTGTCTCCCCTTTAGATTCCTCCATTTTAGGAAGCTTAGATTCCTTCTTT TTAGGAAGCTTTTACACCCTGAATTGGTATGTAACCAGCCCCCTCTTTCCCCCACTGATA AGATATATTGGAGGCGGCCTTTTACTTTTATTCTCTGGACTCCTTTACTGCTATCTCCAT CCAGGAGCCGTTAGGCTCCTGACTCTCATCACTAGGACCACAGCAGAATAAGGGAACAGC ATCTGTGGCTGAGTCACTGGAGGTGGGGGACCGTTAAGAATCAGACACATAATAGCTGAT GTTCATCTTAGACCTTTACTAAGGCTACTTTCCCCATTTCTGGGCTTCAGAAGTCTTGTA ATACATATGAGGGATAGTCACAGCTGGGAGGTGGGGCCAAGAGAAGCCGAAAGTCACATG ACTGTAAGCTGACTAGCAGTTGAGGTGACCTGAGATAGTCGTCTTACCTACAGCTTTGAT GATCTGGCCGCCTTCGAGGCTCTCCTAACCCTTTGGAATCTCTGTTCCCCCTCCCACCTA CCTCCATCTCTCAGGAAACTTTTGACTACATTGGCAGCTCGAGGATGGTCTACGATATGG AGAAGGGCAAGTTTCCCGTGCAGTTAGAGAATGTTGACTCATTTGTGGAGCTGGGACAGG TATGTGGCATGTCCCCCAGCCCCTTCCTTTTTAATTAAATCTTCCTCCTTTGTTGTTCTG CGGTCTTAACTGCAGGAACCACCGCCTCTTCCCTTGACTTCTATCCCCTAGGCATGGCCC AGAACAGGAGACTGATTCTAAGTGTTGTTTCTTCATCCTCCCCCCAGGTGGCCTTAAGAA CTTCATTAGAGCTTTGGATGCACACAGATCCTGTTTCTCAGAAAAATGAGTCTGTACGGA ACCAGGTAACCTGAGCATCTCCCCTCATTTCCTATTCCTACAGCTCAGAATCCAGACCCC AACCCCTGCCCTGTTTCCACCAACCCCCAGGGCCTGTGAGACAGGGTAAGAGACAGGATT GGATTGGGTGTTGGCCAAAGGATGAACACCACAGCTGTTGTTGCTGCTGGGAAGAATCAG GAACTCAGTGACATTCCATTGGTTCCCTGGACTGGGTAGTTCTCTGATCATTTGTTGCCT AGCAGACTACCACTGCCCATTAAGGATAGGTGAGTGACTAGCTCCCTTCTTGCCTTGCTG CCCCATGGATCCAATTGTCAAGGCTGCTCTACCCAAGTCCTGGCTGTGTCACACTCGCTG CCCAACTTGTCCTCCACTTTCCTCATTGCTTGTTCAAAACCTTCCCTTCCCTCTAGGTCC ACCTTTAGGCCTGCTTTTTTCCAGGTGGTCCTCTTTCTGCAATTCCAGCCTTCAGCATCA TCCCTGCTCTGGACTCCTGTAGCATTTAAAGAATTGGTTATCTGTTTGGCATTCAGCACG CAGTTTTCTATTATTATTTGCTCCCTTCAATTCTGCACAATAAATAATAAGTGAAGCATC CACTGAGGATAAAGCAGAGTCTTGAAGACAGTAGAATTTACTTATAAATATGAAAAAAAA GGTCTCTTCTTTATGCCCCAATTTTCTAACTCTAAAAAGAATGGTGGAAGCTACAGGAAA TTCAGAGAGCCTTGGTCCCAAAAGGCTTGAGGGATAAAGGTCTACTAGAGATAGGGTAGC TCCCCAAGCAGGGAACTTGAAGTATAGAGCATTTCAGGCCTAAAAGAGACCTCCTGCTTC CCATCCCCCAGCCTCCCATCAGTTAATCTCCCTCGTACCCCCCAGGTGGAGGATCTCCTG GCCACATTGGAGAAGAGTGGTGCTGGTGTCCCTGCTGTCATCCTCAGGAGGCCAAATCAG TCCCAGCCTCTCCCACCATCTTCCCTGCAGCGATTTCTTCGAGCTCGAAACATCTCTGGC GTTGTTCTGGCTGACCACTCTGGTGCCTTCCATAACAAGTAAGAATCACTTGGCCCTGCA CCCTCTTCATTCTTGAAGAGAGTCTATTCTGCAGTCTGGGAGGAAGGTCACTGCCCTCCG CTTTCCCACACTACCCCCTCCAGAACTTCAGGTCCATCTGTATTCTTTGCTCAGTGGCGT TTTCACATCTGAACTGAAACCCTTATTTGTTTGACTGGATATTCATCTTAGAAACTCATC CTCACCCTTAGCCCTTTACTGTCAACAATCCTTGGTTATGGTTCCACTGCTCCCTAGCTC TCCAGGGTCCTGAGTTCCTCAGGGTTGCCAGCAGAGGGCATCATCTCAAACACAAGCATG GGAAGGATGGTGGGGGCCCTTTGGCTAGAAGACAGAAAGCAGTCCTTCTCTGGAACTCAC CCAGAGGTGCCAGAAACAGTATTCATACTCTGTGAAATGTACCATGTTCTTGCCATGTGG TAGATGGCCATGGTTCAGTGCGAGGGTAAAAGTGCCTCCTATAGCTGATGGGGCTCCAGA GATACAAAGGGTAACTCTGGGTTACCCTTTAACTGCTCCTAACTTGAGGCCTTGGATAAC AGGGGACTTCTTACTCAGGCTGGATTGCCAAGCTTCCCGAGGGCCAAATGAGTTTCGTAG TGAAAATGCTTGAGCTCTATTTCTGACCCCAGCCAAGTAGCACCTTCTCATTCATTTAGG GGAGTGACCGTCCTAGCACTTAGGGTCAGCTGTCTTCTCTAAAGCTATCCTTGTACCACT TTGGGGCAAGTGAAGATTCATCATTTGAACACATTTTGGATTTGATTATGTAGCTGACTT GACTTTGTGTGGGACAGGGATTTACTGATGGTAAAGACTGTGGAGCTCAGCCTCTCTTTT AAGATCTATCTCCTTGGGGCTCCATAAGGATCATCATGGTGATTTTATCAGTGTATTCTT ATATATCAGTGAGCAGACCTGATCCTAAGACCTGCTAATCACCTCCTGCTCCCAGCTACC CTAAATATAAATGTTCATTGGAACAGTTATACAACTGATCTCATGATACATGGCAGAGTT CTCTGAAAATCATCTTAGCCATCCCCCATATCTCCAGCCCAAATGATGTAGAAGAGTCTC TCCTTTGTTTAAAGATCTGAGCTCATTCAGCTTTTCTACCTTGTCTGTCAGGAAAGTCTT TAATTTTCACTAACCACCTCACCCTCACTCCTACCTCCCTGTTCTCCACACCTTCTGCAA TATGGGATCCTGATTGTCTCTCACCCCTTTCTTCTGATGCTGAAAATGAGATACTGAGTC CCTGCATAAGGAGCATTTGAGGGAGGAAAGGGGCAGAGCCCTGGCTAAATGTAGCCAAGG CTCATGCCGGCTTTCCTGGCAGATATTACCAGAGTATTTACGACACTGCTGAGAACATTA ATGTGAGCTATCCCGAATGGCTGAGCCCTGAAGAGGACCTGAACTTTGTAACAGACACTG CCAAGGTAGCACTGAGCCAGGCTGGGTGGGAGCCTGGGGCACACAGTGAAGATGCTAGCA TTTGAGGATAGGAGAGGTGGGCCATTCAGCCCCCTCCTCACCTACCACAGGCCCTGGCAG ATGTGGCCACGGTGCTGGGACGTGCTCTGTATGAGCTTGCAGGAGGAACCAACTTCAGCG ACACAGTTCAGGCTGATCCCCAAACGGTAAGCAGATGGGCCCTAGCTCCTTCTTTCTATT TACACAGCAAGCTGTCCCTATCCTCCCTTGCCCTAGTGTCCCAAACCTTGGAATTCCACA TGACTGTTGATGCCGGTGAGAATGCCTCATGCCCCAGAGAGCTCTTGGGTGGGCCTCATC TGCATCTTATGAGCCAGCTACTGTCTCCCAACTCCAGTCTATCTGGCCAGTCTGGTTCCT GCCCCATGACTGGGTCTCCACTGATAATTCTTTCCCTGGGCTCCCTTCAAGTCACAGGGT TTTCTCTCTTTACTGTTCCAATCCTAGGTTACCCGCCTGCTCTATGGGTTCCTGATTAAA GCCAACAACTCATGGTTCCAGTCTATCCTCAGGCAGGACCTAAGGTCCTACTTGGGTAAG CATCTGGTGTGGGAATGGGACCCTTAGCTGAGGAAAGGGATAGAGAAAAAGTCTTTTGGT TTAACCTTTATTATTTTTTTTCTTTTTCCTCTCTGTTTTTCTTACCCCCTGTTTTCCTTT CTTTCTTCTCATATTTGATGGATCCTTTTCCATTGCCCTTCTTTCTGGCTGCTGCCAATC TTGGGCTTTTCCTATTTCACCCACCATCCACCCACCAAATCTTCCCTTCCCTTTGGTCTG CACTCAGGTGACGGGCCTCTTCAACATTACATCGCTGTCTCCAGCCCCACCAACACCACT TATGTTGTACAGTATGCCTTGGCAAATTTGACTGGCACAGTGGTCAACCTCACCCGAGAG CAGTGCCAGGATCCAAGTAAAGTCCCAAGTGAAAACAAGGATGTGAGTGGTGGTGGGTGT TGGAAGTGCCCTGGGGCCCCTTTCCCTTGGGAAAGTTGGAGGTTCTTCTAGACCTAGTTA GACCCAGGGGATTGGGATGGAGAGGTGGAGAGATGCAGTCCTCAGCAATTGGGTGTTGAA AAGCCTGGGTGAAAATGGACCATCTGAAGGGTAAAGGGACAGCAGCCAGTTAGCTCAATT GGTTAGAGCATGGCACTGATAGAGGGTAGAGGGAACGAGTGAGAAGAGGATCACCCTAGC CGTGTGTTGTGGCGCATCTTCTGTGCAGCTGTATGAGTACTCATGGGTCCAGGGCCCTTT GCATTCTAATGAGACGGACCGACTCCCCCGGTGTGTGCGTTCTACTGCACGATTAGCCAG GGCCTTGTCTCCTGCCTTTGAACTGAGTCAGTGGAGCTCTACTGAATACTCTACATGGAC TGAGAGCCGCTGGAAAGATATCCGTGCCCGGATATTTCTCATCGCCAGCAAAGAGCTTGA GGTGAGATGGGGCAGGGGCATAGGTGGCAGGGATCTGTTTGACTTCTTTCTCTGCTTTCT TGTGTCATATAGCCCTTTCCATCTCCCATTTGCCCCACATTTGTAGCAAAAGCCTACTGC AAATCTGTCCCTGGTCAGCCAGCATGTTCCCTTAGGAGGCCTTTTTTTTGAGATGGAGTT TCATTCTTGTTGCTCAAGCTGGAGTGCAATGGCACAATCTCAGCTTACTGCAACCTCCGT CCCTTGGGTTTAAGCAGTTCTCCTGCCTCAGCCTTTCGAGTAGCTGGGATTACAGGCATG TGTCACCACACCCAGCTAATTTTTTTTTATTTTTAGTAGAGATGGGTTTCACCATGTTGG TCAGGCTAGTCTTAAACTCCTGACCTCAGGTGATCCACCTTTCTTGGCCTCCCAAAGTGC TGGGATTATAGGCGTGAGCCACTGCACCCGGCCAGGAGGCCTTTCTTCACAGATAGTTTG AGTAGGTGTTCATTCTGGAGAGCCCCTGTGGATCCCAGAACTCTTTCACAGCTTCAACTC CCGGCTGGCATTCCCCATCTGGCACAGCTGGGATGAGTCAGTCTAATGTACCGAGCTCCT GTCACAAGTCAGTAATGTAAGTGCCGCAAGGGAACCAAAGCCATGGGCCCTCCTTTCAAA ATGCCTAAAATCTAAGTAATACAAGATGGAAGCAAGAACAGAGATGCTTTACTTCTCTTT TCAAATGGGGAGACAAAGTCTGTAGGCTGGAGAGATGTTGCCCATGATTATTCCATAGTT GGTGCTTAGAGCCAGCATCCGAATTCCCATGGCTCCAAACCCCAAACAGTTATCCAAAAA ACTGCACTGAGTTCTGAGAATGCCTTTGTCCTTTCCTGCCCTCCCTCCCCCTGCAGTTGA TCACCCTGACAGTGGGCTTCGGCATCCTCATCTTCTCCCTCATCGTCACCTACTGCATCA ATGCCAAAGCTGATGTCCTTTTCATTGCTCCCCGGGAGCCAGGAGCTGTGTCATACTGAG GAGGACCCCAGCTTTTCTTGCCAGCTCAGCAGTTCACTTCCTAGAGCATCTGTCCCACTG GGACACAACCACTAATTTGTCACTGGAACCTCCCTGGGCCTGTCTCAGATTGGGATTAAC ATAAAAGAGTGGAACTATCCAAAAGAGACAGGGAGAAATAAATAAATTGCCTCCCTTCCT CCGCTCCCCTTTCCCATCACCCCTTCCCCATTTCCTCTTCCTTCTCTACTCATGCCAGAT TTTGGGATTACAAATAGAAGCTTCTTGCTCCTGTTTAACTCCCTAGTTACCCACCCTAAT TTGCCCTTCAGGACCCTTCTACTTTTTCCTTCCTGCCCTGTACCTCTCTCTGCTCCTCAC CCCCACCCCTGTACCCAGCCACCTTCCTGACTGGGAAGGACATAAAAGGTTTAATGTCAG GGTCAAACTACATTGAGCCCCTGAGGACAGGGGCATCTCTGGGCTGAGCCTACTGTCTCC TTCCCACTGTCCTTTCTCCAGGCCCTCAGATGGCACATTAGGGTGGGCGTGCTGCGGGTG GGTATCCCACCTCCAGCCCACAGTGCTCAGTTGTACTTTTTATTAAGCTGTAATATCTAT TTTTGTTTTTGTCTTTTTCCTTTATTCTTTTTGTAAATATATATATAATGAGTTTCATTA AAATAGATTATCCCACACGA OMIM ID 605254