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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TARDBP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23435
Official gene symbolTARDBP
Full nameTAR DNA binding protein
Aliases,ALS10,TDP-43,
Gene summaryHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.22
Gene position11072679 - 11085549  Map Viewer
Gene orientationplus
Gene size12871 bp
Gene sequence
OMIM ID605078